Alexey Strygin
@strygah.bsky.social
91 followers 17 following 12 posts
founder, executive, vitalist 🧬 longevity biotech, longevity economics, drug discovery, startups
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strygah.bsky.social
I used to need alcohol as a social lubricant when I was younger.

Now I'm the social lubricant myself.
strygah.bsky.social
🚨🚨🚨
Reflections on Zelar.City are out! The organizing team was
interviewed during the final days of the 5-week event and daily deep convos

We reflect on longevity industry and pop cities

A MUST SEE

www.youtube.com/watch?v=T5pc...
We build a Longevity Pop-up City - Zelar.city team interview
YouTube video by Elias Schlie (Longevity)
www.youtube.com
strygah.bsky.social
Is it just me, or am I uncovering new reasons to pursue radical life extension? 🤔

(Of course, we're talking about biological age in theoretical high calendar-year-old 25-year-olds!)

Paper for reference:
doi.org/10.1101/cshp...
International Gains to Achieving Healthy Longevity
doi.org
strygah.bsky.social
1️⃣ It's way better to be a woman!
2️⃣ If you're a man lucky enough to live to 5,000 years, you're in a world where there are three 25-year-old Japanese women for every one of you!
3️⃣ If you've made it to 10,000 years, the number of women per man is ~7.5.
strygah.bsky.social
3️⃣ We also know there are big differences between male and female mortality rates. I found the mortality rates for 25-year-olds in Japan (0.02% for women, 0.04% for men) and plotted a graph. What do we observe?
strygah.bsky.social
2️⃣ There's a huge variation in lifespan (see the survival curve I modeled):

Half the people will die before reaching 1,214.5 years
18% will live up to 3,000 years
5.78% will make it to 5,000 years
0.33% will reach 10,000 years
strygah.bsky.social
1️⃣ Even when we remove aging from the equation, there are still chances of dying (from infections, violence, accidents, and cancers). For 30-year-olds, the mortality rate in the paper is about ~0.057% per year, aligning with data from developed countries like Japan.
strygah.bsky.social
Reversing one year of aging per year essentially hits the Longevity Escape Velocity point. In this scenario, the expected lifespan for 30-year-olds is 1,782.6 years.

Way better than now!

But there are important nuances (I played around with the data for you): 📊
strygah.bsky.social
I've been digging into Andrew Scott's paper and found an interesting table modeling a theoretical therapy applied once a year that regenerates either 1 year, 9 months, 6 months, or 3 months of aging at different ages (see table).
🧵
strygah.bsky.social
My pronouns are “fuck/death”
strygah.bsky.social
Who is here from longevity biotech?
strygah.bsky.social
How do get banned here? Can I joke?