Suel-Kee Kim
@suelkeekim.bsky.social
Neuroscientist, Sestan Lab @yaleneuro.bsky.social, Brain Development and Evolution, Human-Specific Features, #Cerebellum, Pluripotent Stem Cells, #iPSC, Individual Variation
Pinned
Suel-Kee Kim
@suelkeekim.bsky.social
· Sep 9
Human-specific features of the cerebellum and ZP2-regulated synapse development
Understanding the unique features of the human brain compared to non-human primates has long intrigued humankind. The cerebellum refines motor coordination and cognitive functions, contributing to the...
www.biorxiv.org
Excited to share our recent study on human-specific features of the cerebellum and the unexpected, novel role of zona pellucida protein 2 (ZP2) in synapse development. Grateful to the Sestan lab and all our collaborators for their outstanding contributions. www.biorxiv.org/content/10.1...
Reposted by Suel-Kee Kim
NEXT TUE: DDD seminar, Nov. 18, 2025 @ 1PM Eastern US: Continuing our focus on approaches to the study of many pluripotent stem cell lines, Dr. Michael Wells @mfwells.bsky.social will share his recent work on "cell villages". seminar info: carlocolantuoni.org/seminar [repost to spread the word]
SeminarPage | Carlo Colantuoni
carlocolantuoni.org
November 11, 2025 at 6:10 PM
NEXT TUE: DDD seminar, Nov. 18, 2025 @ 1PM Eastern US: Continuing our focus on approaches to the study of many pluripotent stem cell lines, Dr. Michael Wells @mfwells.bsky.social will share his recent work on "cell villages". seminar info: carlocolantuoni.org/seminar [repost to spread the word]
Reposted by Suel-Kee Kim
NEXT TUE: DDD seminar, Oct. 14, 2025 @ 1PM Eastern US: Continuing our focus on variation in early fate decisions and CNS regionalization, Dr. Alex Pollen will share his recent work on cross-species midbrain dopaminergic organoids. seminar info: carlocolantuoni.org/seminar -repost to spread the word
SeminarPage | Carlo Colantuoni
carlocolantuoni.org
October 8, 2025 at 5:54 PM
NEXT TUE: DDD seminar, Oct. 14, 2025 @ 1PM Eastern US: Continuing our focus on variation in early fate decisions and CNS regionalization, Dr. Alex Pollen will share his recent work on cross-species midbrain dopaminergic organoids. seminar info: carlocolantuoni.org/seminar -repost to spread the word
Reposted by Suel-Kee Kim
In a new @natcomms.nature.com study, @yaleneuro.bsky.social's Nicola Micali from the Rakic lab, alongside a team of researchers @prbb.org, found that many genes 🧬 linked to mental illness 🧠 are turned ON in neural stem cells as early as the first trimester.👶
Origins of mental illness, fast gas for a black hole
Yale researchers discover a gas guzzling black hole, learn that mental illness may start to develop earlier than once thought, and explore why some brain seizures cause a loss of consciousness.
news.yale.edu
September 23, 2025 at 4:45 PM
In a new @natcomms.nature.com study, @yaleneuro.bsky.social's Nicola Micali from the Rakic lab, alongside a team of researchers @prbb.org, found that many genes 🧬 linked to mental illness 🧠 are turned ON in neural stem cells as early as the first trimester.👶
Reposted by Suel-Kee Kim
#aECM (apical extracellular matrix) is a subset of #ECMatrix that is distinct from stromal matrices or basement membranes. Anybody out there studying #mucins #ZPproteins #cuticle #glycocalyx #surfactant or the like? We need to find each other and start talking!
November 16, 2024 at 2:06 PM
#aECM (apical extracellular matrix) is a subset of #ECMatrix that is distinct from stromal matrices or basement membranes. Anybody out there studying #mucins #ZPproteins #cuticle #glycocalyx #surfactant or the like? We need to find each other and start talking!
Reposted by Suel-Kee Kim
There is so much cool #aECM work going on but most of the researchers don’t know or talk to each other; this is an attempt to change that! Link below
... a new virtual seminar series on apical extracellular matrix #aECM on different #organisms 🪱🪰🐁🌱🦠will start in Fall 2025, with short talks and discussions
If you are interested
👉https://forms.gle/Y6UjbnXPH1pDHAE97
@meera-sundaram.bsky.social @gotworms.bsky.social @heiman.bsky.social
If you are interested
👉https://forms.gle/Y6UjbnXPH1pDHAE97
@meera-sundaram.bsky.social @gotworms.bsky.social @heiman.bsky.social
July 17, 2025 at 12:14 PM
There is so much cool #aECM work going on but most of the researchers don’t know or talk to each other; this is an attempt to change that! Link below
Excited to share our recent study on human-specific features of the cerebellum and the unexpected, novel role of zona pellucida protein 2 (ZP2) in synapse development. Grateful to the Sestan lab and all our collaborators for their outstanding contributions. www.biorxiv.org/content/10.1...
Human-specific features of the cerebellum and ZP2-regulated synapse development
Understanding the unique features of the human brain compared to non-human primates has long intrigued humankind. The cerebellum refines motor coordination and cognitive functions, contributing to the...
www.biorxiv.org
September 9, 2025 at 4:49 PM
Excited to share our recent study on human-specific features of the cerebellum and the unexpected, novel role of zona pellucida protein 2 (ZP2) in synapse development. Grateful to the Sestan lab and all our collaborators for their outstanding contributions. www.biorxiv.org/content/10.1...
Reposted by Suel-Kee Kim
NEXT TUE: DDD seminar, Sept. 16, 2025 @ 1PM Eastern US:
Continuing our focus on early fate decisions and CNS regionalization, next Tuesday Sept. 16th at 1PM Eastern US time, Gaurav Rathore (from Angete Kirkeby's group) will share his recent work. seminar info: carlocolantuoni.org/seminar.
Continuing our focus on early fate decisions and CNS regionalization, next Tuesday Sept. 16th at 1PM Eastern US time, Gaurav Rathore (from Angete Kirkeby's group) will share his recent work. seminar info: carlocolantuoni.org/seminar.
SeminarPage | Carlo Colantuoni
carlocolantuoni.org
September 8, 2025 at 12:26 PM
NEXT TUE: DDD seminar, Sept. 16, 2025 @ 1PM Eastern US:
Continuing our focus on early fate decisions and CNS regionalization, next Tuesday Sept. 16th at 1PM Eastern US time, Gaurav Rathore (from Angete Kirkeby's group) will share his recent work. seminar info: carlocolantuoni.org/seminar.
Continuing our focus on early fate decisions and CNS regionalization, next Tuesday Sept. 16th at 1PM Eastern US time, Gaurav Rathore (from Angete Kirkeby's group) will share his recent work. seminar info: carlocolantuoni.org/seminar.
Reposted by Suel-Kee Kim
today's discussion of CNS regionalization and its modeling in vitro is now online at:
www.youtube.com/playlist?lis...
www.youtube.com/playlist?lis...
Developmental Diversity in a Dish Seminar Series - YouTube
A virtual seminar series focusing on stem cell models and functional variation across human iPSC lines. Monthly virtual seminar series, held on one Tuesday o...
www.youtube.com
August 19, 2025 at 8:43 PM
today's discussion of CNS regionalization and its modeling in vitro is now online at:
www.youtube.com/playlist?lis...
www.youtube.com/playlist?lis...
Reposted by Suel-Kee Kim
Linking alterations in precursor cells of brain 🧠 formation with the origin of #neuropsychiatricdiseases
#bioinformàtica #neuropsiquiatria #salutmental #autisme #Alzheimer #TalentMAR @santperelab.bsky.social @yaleneuro.bsky.social @hospitaldelmar.bsky.social
www.researchmar.net/news/742/lin...
#bioinformàtica #neuropsiquiatria #salutmental #autisme #Alzheimer #TalentMAR @santperelab.bsky.social @yaleneuro.bsky.social @hospitaldelmar.bsky.social
www.researchmar.net/news/742/lin...
July 25, 2025 at 7:09 AM
Linking alterations in precursor cells of brain 🧠 formation with the origin of #neuropsychiatricdiseases
#bioinformàtica #neuropsiquiatria #salutmental #autisme #Alzheimer #TalentMAR @santperelab.bsky.social @yaleneuro.bsky.social @hospitaldelmar.bsky.social
www.researchmar.net/news/742/lin...
#bioinformàtica #neuropsiquiatria #salutmental #autisme #Alzheimer #TalentMAR @santperelab.bsky.social @yaleneuro.bsky.social @hospitaldelmar.bsky.social
www.researchmar.net/news/742/lin...
Reposted by Suel-Kee Kim
Excited to share our latest work, spearheaded by my brilliant student Xoel Mato and co-led by Nicola Micali. After years of sweat, intense weekly meetings, and meticulous discussion of every panel, we learned a lot from each other. Grateful for the journey!
@researchmar.bsky.social
rdcu.be/evCaU
@researchmar.bsky.social
rdcu.be/evCaU
Early developmental origins of cortical disorders modeled in human neural stem cells
Nature Communications - The implications of early telencephalic development in cortical disorders remain elusive. Here, the authors define risk gene dynamics and perturbation effects in neural stem...
rdcu.be
July 10, 2025 at 6:24 AM
Excited to share our latest work, spearheaded by my brilliant student Xoel Mato and co-led by Nicola Micali. After years of sweat, intense weekly meetings, and meticulous discussion of every panel, we learned a lot from each other. Grateful for the journey!
@researchmar.bsky.social
rdcu.be/evCaU
@researchmar.bsky.social
rdcu.be/evCaU
Excited to share our latest work, Mato-Blanco et al., nature.com/articles/s41.... Thanks to the incredible collaboration with Nicola Micali, Rakic lab, Sestan lab, Vaccarino lab
@yaleneuro.bsky.social @santperelab.bsky.social @carlocolantuoni.bsky.social
@yaleneuro.bsky.social @santperelab.bsky.social @carlocolantuoni.bsky.social
Early developmental origins of cortical disorders modeled in human neural stem cells - Nature Communications
The implications of early telencephalic development in cortical disorders remain elusive. Here, the authors define risk gene dynamics and perturbation effects in neural stem cells, revealing vulnerabi...
nature.com
July 9, 2025 at 11:11 PM
Excited to share our latest work, Mato-Blanco et al., nature.com/articles/s41.... Thanks to the incredible collaboration with Nicola Micali, Rakic lab, Sestan lab, Vaccarino lab
@yaleneuro.bsky.social @santperelab.bsky.social @carlocolantuoni.bsky.social
@yaleneuro.bsky.social @santperelab.bsky.social @carlocolantuoni.bsky.social
Reposted by Suel-Kee Kim
NEXT TUE: DDD seminar, July 8, 2025 @ 1PM Eastern US: Dr. Alessandro Vitriolo @alessandrovitriolo.bsky.social (Lab of Dr. Giuseppe Testa) “Regulatory logic of human cortex evolution by combinatorial perturbations”. seminar info: carlocolantuoni.org/seminar [repost to spread the word]
SeminarPage | Carlo Colantuoni
carlocolantuoni.org
July 1, 2025 at 9:39 PM
NEXT TUE: DDD seminar, July 8, 2025 @ 1PM Eastern US: Dr. Alessandro Vitriolo @alessandrovitriolo.bsky.social (Lab of Dr. Giuseppe Testa) “Regulatory logic of human cortex evolution by combinatorial perturbations”. seminar info: carlocolantuoni.org/seminar [repost to spread the word]
Reposted by Suel-Kee Kim
Thrilled to present MIND!
A model for how the sensorimotor–association axis of the neocortex develops.
Huge thanks to the incredible multidisciplinary team who made this happen.
www.biorxiv.org/content/10.1...
A model for how the sensorimotor–association axis of the neocortex develops.
Huge thanks to the incredible multidisciplinary team who made this happen.
www.biorxiv.org/content/10.1...
Competing Programs Shape Cortical Sensorimotor-Association Axis Development
The neocortex is organized along a dominant sensorimotor-to-association (S-A) axis, anchored by modality-specific primary sensorimotor areas at one end and transmodal association areas that form distr...
www.biorxiv.org
July 1, 2025 at 5:29 PM
Thrilled to present MIND!
A model for how the sensorimotor–association axis of the neocortex develops.
Huge thanks to the incredible multidisciplinary team who made this happen.
www.biorxiv.org/content/10.1...
A model for how the sensorimotor–association axis of the neocortex develops.
Huge thanks to the incredible multidisciplinary team who made this happen.
www.biorxiv.org/content/10.1...
Reposted by Suel-Kee Kim
NEXT TUE: DDD seminar, June 10, 2025 @ 1PM Eastern US: Dr. Magdalena Sutcliffe (lab of Dr. M Lancaster @lancasterlab.bsky.social) “Epigenetic restoration of differentiation competency via reversal of epiblast regionalisation”. seminar info: carlocolantuoni.org/seminar [repost to spread the word]
SeminarPage | Carlo Colantuoni
carlocolantuoni.org
June 4, 2025 at 5:31 PM
NEXT TUE: DDD seminar, June 10, 2025 @ 1PM Eastern US: Dr. Magdalena Sutcliffe (lab of Dr. M Lancaster @lancasterlab.bsky.social) “Epigenetic restoration of differentiation competency via reversal of epiblast regionalisation”. seminar info: carlocolantuoni.org/seminar [repost to spread the word]
Reposted by Suel-Kee Kim
Excited to showcase as a co-first author our latest work "Adaptive Evolution of Gene Regulatory Networks in Mammalian Neocortical Neurons "https://www.biorxiv.org/content/10.1101/2025.05.20.652233v1
May 22, 2025 at 5:43 PM
Excited to showcase as a co-first author our latest work "Adaptive Evolution of Gene Regulatory Networks in Mammalian Neocortical Neurons "https://www.biorxiv.org/content/10.1101/2025.05.20.652233v1
Reposted by Suel-Kee Kim
The recording of today's DDD seminar by Dr. Ron McKay “Origin and consequences of genetically distinct behaviors in human neural stem cells” is now online at: www.youtube.com/playlist?lis...
Developmental Diversity in a Dish Seminar Series - YouTube
A virtual seminar series focusing on stem cell models and functional variation across human iPSC lines. Monthly virtual seminar series, held on one Tuesday o...
www.youtube.com
May 6, 2025 at 8:12 PM
The recording of today's DDD seminar by Dr. Ron McKay “Origin and consequences of genetically distinct behaviors in human neural stem cells” is now online at: www.youtube.com/playlist?lis...
Reposted by Suel-Kee Kim
Thrilled to share our latest study out in @natureportfolio.nature.com led by the fantastically talented Jing Liu. Our study provides insight into a long standing question in biology: What molecular features make us uniquely human and how do these function? www.nature.com/articles/s41...
A human-specific enhancer fine-tunes radial glia potency and corticogenesis - Nature
HARE5, a human accelerated region enhancer, modulates cortical development by influencing neural progenitor cell behaviour, leading to an enlarged neocortex with increased functional independence betw...
www.nature.com
May 14, 2025 at 4:09 PM
Thrilled to share our latest study out in @natureportfolio.nature.com led by the fantastically talented Jing Liu. Our study provides insight into a long standing question in biology: What molecular features make us uniquely human and how do these function? www.nature.com/articles/s41...
Reposted by Suel-Kee Kim
Today in @nature.com , we report a spatial single-cell atlas of human cortical development, revealing surprisingly early specification of human cortical layers and areas.
We built an interactive browser to explore the spatial data: walshlab.org/research/cor...
Paper link below 👇
We built an interactive browser to explore the spatial data: walshlab.org/research/cor...
Paper link below 👇
May 14, 2025 at 5:24 PM
Today in @nature.com , we report a spatial single-cell atlas of human cortical development, revealing surprisingly early specification of human cortical layers and areas.
We built an interactive browser to explore the spatial data: walshlab.org/research/cor...
Paper link below 👇
We built an interactive browser to explore the spatial data: walshlab.org/research/cor...
Paper link below 👇
Reposted by Suel-Kee Kim
NEXT TUE: DDD seminar, May 6, 2025 @ 1PM Eastern US: Dr. Ron McKay “Origin and consequences of genetically distinct behaviors in human neural stem cells”. seminar info: carlocolantuoni.org/seminar [repost to spread the word]
SeminarPage | Carlo Colantuoni
carlocolantuoni.org
April 29, 2025 at 10:38 PM
NEXT TUE: DDD seminar, May 6, 2025 @ 1PM Eastern US: Dr. Ron McKay “Origin and consequences of genetically distinct behaviors in human neural stem cells”. seminar info: carlocolantuoni.org/seminar [repost to spread the word]
Reposted by Suel-Kee Kim
NEXT TUE: DDD seminar, Apr. 1, 2025 @ 1PM Eastern US: Dr. Jason Stein steinlab.bsky.social “Modeling genetics altering human cortical structure”. seminar info: carlocolantuoni.org/seminar [repost to spread the word]
SeminarPage | Carlo Colantuoni
carlocolantuoni.org
March 26, 2025 at 8:56 PM
NEXT TUE: DDD seminar, Apr. 1, 2025 @ 1PM Eastern US: Dr. Jason Stein steinlab.bsky.social “Modeling genetics altering human cortical structure”. seminar info: carlocolantuoni.org/seminar [repost to spread the word]
Reposted by Suel-Kee Kim
Navjot Kaur
I am thrilled to share our latest paper from Sestan lab on the development of the claustro-amygdalar complex, is published at nature.com/articles/s41.... A big thank you to all our collaborators and mentors.
@marinap63.bsky.social
I am thrilled to share our latest paper from Sestan lab on the development of the claustro-amygdalar complex, is published at nature.com/articles/s41.... A big thank you to all our collaborators and mentors.
@marinap63.bsky.social
Specification of claustro-amygdalar and palaeocortical neurons and circuits - Nature
A conserved gene regulatory network involving SOX4, SOX11 and TFAP2D shapes the development of excitatory neurons in ventrolateral pallium and their connectivity with the prefrontal cortex.
nature.com
January 15, 2025 at 8:14 PM
Navjot Kaur
I am thrilled to share our latest paper from Sestan lab on the development of the claustro-amygdalar complex, is published at nature.com/articles/s41.... A big thank you to all our collaborators and mentors.
@marinap63.bsky.social
I am thrilled to share our latest paper from Sestan lab on the development of the claustro-amygdalar complex, is published at nature.com/articles/s41.... A big thank you to all our collaborators and mentors.
@marinap63.bsky.social
Reposted by Suel-Kee Kim
📢The YC-SCAN² has awarded 14 grants 💰 to researchers, including @yaleneuro.bsky.social's Nicola Micali & @mhigley.bsky.social 👨🔬🥼, for their work focused on understanding the impact of cannabinoids on neurodevelopment!
Read More Here 👇
Read More Here 👇
https://medicine.yale.edu/brain-mind-health/news-article/yale-center-for-the-science-of-cannabis-and-cannabinoids-announces-inaugural-pilot-award-winners/"
December 9, 2024 at 8:08 PM
📢The YC-SCAN² has awarded 14 grants 💰 to researchers, including @yaleneuro.bsky.social's Nicola Micali & @mhigley.bsky.social 👨🔬🥼, for their work focused on understanding the impact of cannabinoids on neurodevelopment!
Read More Here 👇
Read More Here 👇