Takuya Azami
@tazami.bsky.social
Developmental biologist at MRC Human Genetics Unit, Institute of Genetics and Cancer, The University of Edinburgh.
Happy to share our new preprint!
Simplified In Vitro Generation of Human Gastruloids for Modelling Early Development https://www.biorxiv.org/content/10.1101/2025.10.15.682610v1
October 16, 2025 at 4:53 AM
Happy to share our new preprint!
Reposted by Takuya Azami
1/10🧵 New preprint! 🚀
We built a resource of 20 clonal human naïve pluripotent stem cell lines from 10 blastocysts. Explore embryo-to-embryo and clone-to-clone variation in one place.
👉doi.org/10.1101/2025.06.02.657331
We built a resource of 20 clonal human naïve pluripotent stem cell lines from 10 blastocysts. Explore embryo-to-embryo and clone-to-clone variation in one place.
👉doi.org/10.1101/2025.06.02.657331
June 4, 2025 at 6:17 PM
1/10🧵 New preprint! 🚀
We built a resource of 20 clonal human naïve pluripotent stem cell lines from 10 blastocysts. Explore embryo-to-embryo and clone-to-clone variation in one place.
👉doi.org/10.1101/2025.06.02.657331
We built a resource of 20 clonal human naïve pluripotent stem cell lines from 10 blastocysts. Explore embryo-to-embryo and clone-to-clone variation in one place.
👉doi.org/10.1101/2025.06.02.657331
Reposted by Takuya Azami
STAT3 signaling enhances tissue expansion during postimplantation mouse development
STAT3 signaling enhances tissue expansion during postimplantation mouse development
Azami et al. reveal that STAT3 deletion depletes epiblast cells at implantation, causing a persistent developmental delay of around a day. STAT3 null embryonic stem cells contribute to all embryonic tissues in chimeras except blood. Mixing with wild-type cells for in vitro erythroid differentiation causes the outcompetition of STAT3 null cells.
dlvr.it
April 8, 2025 at 2:38 PM
STAT3 signaling enhances tissue expansion during postimplantation mouse development
Happy to share our study on Stat3, now published in Cell Reports!
Huge thanks to all collaborators!
www.cell.com/cell-reports...
Huge thanks to all collaborators!
www.cell.com/cell-reports...
STAT3 signaling enhances tissue expansion during postimplantation mouse development
Azami et al. reveal that STAT3 deletion depletes epiblast cells at implantation, causing
a persistent developmental delay of around a day. STAT3 null embryonic stem cells
contribute to all embryonic t...
www.cell.com
April 7, 2025 at 1:31 PM
Happy to share our study on Stat3, now published in Cell Reports!
Huge thanks to all collaborators!
www.cell.com/cell-reports...
Huge thanks to all collaborators!
www.cell.com/cell-reports...