Sri Krishna (Krish)
@tellkrish.bsky.social
Stadtman Investigator @ Surgery Branch, NCI | Immunology & Cancer, T Cells & Mutations |
Views don't represent NIH, HHS or US GOV
|🇮🇳🇺🇸| Lab: https://ccr.cancer.gov/staff-directory/sri-krishna
Views don't represent NIH, HHS or US GOV
|🇮🇳🇺🇸| Lab: https://ccr.cancer.gov/staff-directory/sri-krishna
A huge loss to science.
www.nytimes.com/2025/09/07/s...
www.nytimes.com/2025/09/07/s...
David Baltimore, Nobel-Winning Molecular Biologist, Dies at 87
www.nytimes.com
September 8, 2025 at 1:18 AM
A huge loss to science.
www.nytimes.com/2025/09/07/s...
www.nytimes.com/2025/09/07/s...
Very cool study
Here is link to Shixin's new paper: www.science.org/doi/epdf/10....
Nutrient-driven histone code determines exhausted CD8+ T cell fates
ACLY-deficient CAR T cells targeting the tumor-associated antigen disialoganglioside GD2 (GD2 CAR T cells) also resisted acquiring TEX-like properties, exhibiting reduced CD39 expression when co-cultu...
www.science.org
December 16, 2024 at 3:40 PM
Very cool study
ICYMI - over the summer Maria Parkhurst from our branch published one of the first reports of clinical responses after adoptive cell transfer of TCR engineered private neoantigen (tumor mutation) targeting T cells in metastatic cancer patients 🧪🦠🔬🩺 1/3 #Immunosky
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Adoptive transfer of personalized neoantigen-reactive TCR-transduced T cells in metastatic colorectal cancer: phase 2 trial interim results - Nature Medicine
Preliminary findings in seven patients with mismatch repair-proficient metastatic colorectal cancer who were treated in the context of a phase 2 trial show that adoptive transfer of autologous periphe...
www.nature.com
November 24, 2024 at 5:02 PM
ICYMI - over the summer Maria Parkhurst from our branch published one of the first reports of clinical responses after adoptive cell transfer of TCR engineered private neoantigen (tumor mutation) targeting T cells in metastatic cancer patients 🧪🦠🔬🩺 1/3 #Immunosky
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposting this now that there’s more crowd here - it was lonely a year back 🧪🦠
Hi Bluesky. I recently started my lab at the Surgery Branch, National Cancer Institute. We study T cell Immunology in human cancer patients with the goal of developing cell therapies. Pls share this, join us if you're interested! We are looking for postdocs! ccr.cancer.gov/staff-direct...
November 16, 2024 at 11:22 PM
Reposting this now that there’s more crowd here - it was lonely a year back 🧪🦠
Can we find antitumor, neoantigenT cells and predict their TCRs in the blood of patients with metastatic solid tumors? How do their phenotypes compare to those within patient's tumor? We addressed these questions in our new Cancer_Cell study.
Phenotypic signatures of circulating neoantigen-reactive CD8+ T cells in patients with metastatic c...
Circulating T cells from peripheral blood (PBL) can provide a rich and noninvasive source for antitumor T cells. By single-cell transcriptomic profili…
www.sciencedirect.com
December 2, 2023 at 6:53 PM
Can we find antitumor, neoantigenT cells and predict their TCRs in the blood of patients with metastatic solid tumors? How do their phenotypes compare to those within patient's tumor? We addressed these questions in our new Cancer_Cell study.
Another day, another award for our branch chief Steve Rosenberg. This time, the Presidential National Medal of technology and innovation, for pioneering immunotherapy against cancer.
🧪🔬🦠🩺 #ImmunoSky
www.cancer.gov/news-events/...
🧪🔬🦠🩺 #ImmunoSky
www.cancer.gov/news-events/...
October 24, 2023 at 4:19 PM
Another day, another award for our branch chief Steve Rosenberg. This time, the Presidential National Medal of technology and innovation, for pioneering immunotherapy against cancer.
🧪🔬🦠🩺 #ImmunoSky
www.cancer.gov/news-events/...
🧪🔬🦠🩺 #ImmunoSky
www.cancer.gov/news-events/...
As probably one of the few NIH researchers on here, I feel obligated to note that a US federal govt shutdown will also impact the approx 1500 clinical trials being conducted at the NIH, including those against cancer, Alzheimer's, and many other diseases. Hopefully it is averted. 🩺🦠🔬🧪
September 29, 2023 at 1:25 PM
As probably one of the few NIH researchers on here, I feel obligated to note that a US federal govt shutdown will also impact the approx 1500 clinical trials being conducted at the NIH, including those against cancer, Alzheimer's, and many other diseases. Hopefully it is averted. 🩺🦠🔬🧪
🧪🔬🦠🩺Pls share. We are evaluating postdoc candidates with interests computational or experimental immunology, or tumor biology, immunotherapy, T cell immunology, or genome engineering. ccr.cancer.gov/careers/post...
September 19, 2023 at 9:37 PM
🧪🔬🦠🩺Pls share. We are evaluating postdoc candidates with interests computational or experimental immunology, or tumor biology, immunotherapy, T cell immunology, or genome engineering. ccr.cancer.gov/careers/post...
Hi Bluesky. I recently started my lab at the Surgery Branch, National Cancer Institute. We study T cell Immunology in human cancer patients with the goal of developing cell therapies. Pls share this, join us if you're interested! We are looking for postdocs! ccr.cancer.gov/staff-direct...
September 13, 2023 at 1:59 AM
Hi Bluesky. I recently started my lab at the Surgery Branch, National Cancer Institute. We study T cell Immunology in human cancer patients with the goal of developing cell therapies. Pls share this, join us if you're interested! We are looking for postdocs! ccr.cancer.gov/staff-direct...