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The Journal of Pain @thejournalofpain.bsky.social · 1d

Original: Drs. Tamang, @link_physio et al. found that in Bhutanese patients with
musculoskeletal pain, the Faces Pain Scale–Revised was most valid, reliable, and
preferred compared to others clinical used scales.

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The Journal of Pain @thejournalofpain.bsky.social · 1d

Original: Kalingel Levi et al. developed the Pain Awareness Scale, a novel psychometrically validated measure of pain awareness in autistic adults.

FULL: www.jpain.org/article/S152...

The Journal of Pain @thejournalofpain.bsky.social · 3d

Original: Drs. Bharmauria, Flouty & al. showed that high-freq spinal cord stimulation alters cortical activity by suppressing high-freq oscillations and selectively modulating low-freq rhythms

— Supraspinal pathways may drive the analgesia

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Neurophysiological effects of high-frequency spinal cord stimulation on cortico-sensory areas in large ovine animal model

Spinal Cord Stimulation (SCS) has been a cornerstone in managing chronic pain since the late 1960s. However, traditional SCS is often associated with variable efficacy and side effects, driving the…

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The Journal of Pain @thejournalofpain.bsky.social · 4d

Original: Dr. Smith, Farris & coll. showed that over 10% of Medicare beneficiaries had Chronic overlapping pain conditions (COPC), but only 1/4 received targeted treatment

— Black and Asian were underdiagnosed yet more likely to get prescriptions

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Disparities in diagnosis and management of chronic overlapping pain conditions in an observational study of medicare beneficiaries

Disparities in care and management of pain among racial groups have been demonstrated in various studies. Chronic overlapping pain conditions (COPCs) have yet to be examined. This was an…

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The Journal of Pain @thejournalofpain.bsky.social · 5d

Original: Grant et al. uncovered that providers’ intentions to provide guideline-recommended pain care arise from the combined influence of factors internal to providers

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Factors affecting the provision of guideline-recommended pain care in rural Australia: A consolidated program theory from a realist needs assessment

Little research has investigated what factors affect rural healthcare providers’ provision of guideline-recommended pain care. The authorship team developed a realist approach to conducting a needs…

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The Journal of Pain @thejournalofpain.bsky.social · 8d

Original: Dr. Woods et al. identified links between supportive and strained family relationships and ways in which aging Black adults’ pain unfolds over time

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The Journal of Pain @thejournalofpain.bsky.social · 9d

Original: Yao et al. conducted a longitudinal study highlighting the importance of chronic pain trajectories in predicting cardiovascular disease

FULL: www.jpain.org/article/S152...

The Journal of Pain @thejournalofpain.bsky.social · 10d

Original: Drs. Zhang , Yang et al. showed that patients with trigeminal neuralgia show altered amygdala fiber pathways.

— These changes partly explain how anxiety and catastrophizing amplify facial pain

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Abnormal white matter microstructure in the amygdala-related fiber tract pathways in patients with trigeminal neuralgia: A multivariate analysis

Trigeminal neuralgia (TN) is characterized by recurrent, severe facial pain often accompanied by negative emotional states such as anxiety and depression. However, the neurobiological mechanisms…

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The Journal of Pain @thejournalofpain.bsky.social · 11d

Original: Dr. Pluma-Pluma, Murbartián et al. showed that chronic stress increases pain by activating glucocorticoid receptors and inflammatory pathways

-Blocking GR or removing adrenal hormones protects against stress-induced allodynia

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Glucocorticoid receptor dynamics and neuroinflammation in chronic restraint stress-induced mechanical allodynia in female rats

Chronic stress increases pain in humans and rodents. It is associated with microglial activation, inflammatory mediators (like HMGB1, TNFα, and IL-1β) production, and alterations in the…

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The Journal of Pain @thejournalofpain.bsky.social · 12d

Original: Dr. @guilleceniza.bsky.social & colleagues provide insight into the high prevalence of chronic postsurgical pain in youth, with rates of 35% at 3 months decreasing to 12% at 24 months

FULL: www.jpain.org/article/S152...

The Journal of Pain @thejournalofpain.bsky.social · 15d

Original: Dr. Wang et al. identified body region differences in temporal summation of pain and associated gamma-band EEG responses elicited by contactless painful laser stimulation

FREE: www.jpain.org/article/S152...

The Journal of Pain @thejournalofpain.bsky.social · 16d

Original: Dr. Zhou, Li &al. found that Kv7.2 (KCNQ2) channels in DRG neurons regulate post-op pain:

— after surgery, KCNQ2 channels drop in pain neurons, boosting excitability
— restoring them with retigabine or miR-106b-5p inhibition relieves pain

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miR-106b-5p downregulate KCNQ2 expression contributing to incisional pain in male rats

The Kv7 (KCNQ) K+ channels family controls neuron excitability, making them significant targets in pain management. This study aims to investigate the potential role of Kv7.2 (KCNQ2) in regulating…

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The Journal of Pain @thejournalofpain.bsky.social · 17d

Focus: Drs. Cherup & Finan examine the potential of psilocybin to enhance patient engagement in chronic pain rehabilitation by modulating self-perception & meaning-making processes

FULL: www.jpain.org/article/S152...

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The Journal of Pain @thejournalofpain.bsky.social · 18d

Focus: Ooghe and colleagues highlight the critical yet underutilized role of covariate adjustment in enhancing the sensitivity of clinical trials

- Offers a structured approach to optimize its use

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The Journal of Pain @thejournalofpain.bsky.social · 18d

Featured: Li et al. demonstrated that the Ba-Duan-Jin may provide additional option for the multidisciplinary management of fibromyalgia patients

FULL: www.jpain.org/article/S152...

The Journal of Pain @thejournalofpain.bsky.social · 26d

Original: @brianpulling.bsky.social et al. developed an Osteoarthritis Conceptualisation Questionnaire to assess an individual’s framework for OA via psychometric evaluation of an established item-bank.

Phase 3: www.jpain.org/article/S152...

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The Journal of Pain @thejournalofpain.bsky.social · 29d

Original: @brianpulling.bsky.social et al. developed an Osteoarthritis Conceptualisation Questionnaire to assess an individual’s framework for OA via psychometric evaluation of an established item-bank.

Phase 2: www.jpain.org/article/S152...

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The Journal of Pain @thejournalofpain.bsky.social · Sep 11

Original: Pistolesi, Drs. Chiarugi et al. found that sumatriptan crosses the BBB, reaching brainstem regions, reduces opioid withdrawal and hyperalgesia in rats, suggesting its therapeutic effects also involve central neuromodulation

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The Journal of Pain @thejournalofpain.bsky.social · Sep 10

Original: Mazzocca et al. report on the content, characteristics, and engagement metrics of the top 100 TikTok videos pertaining to women’s pain

— Strong negative trends were observed

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The Journal of Pain @thejournalofpain.bsky.social · Sep 9

Original: Liang, Drs. @cbooker.bsky.social & coll. highlight that blunted diurnal cortisol declines after waking were linked to a higher risk of developing chronic multisite pain

— HPA axis dysfunction may contribute to pain chronification

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The Journal of Pain @thejournalofpain.bsky.social · Sep 8

Original: Gustafson et al. used qualitative interviews to identify key indicators caregivers use when assessing pain in young children

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The Journal of Pain @thejournalofpain.bsky.social · Sep 5

Original: Drs. Zhang, Shen et al. found that engineered exosomes carrying siRNAs against NMDAR subunits NR2A/B targeted trigeminal neurons and reduced excitability, effectively relieving orofacial neuropathic pain in a mouse model

Full: www.jpain.org/article/S152...

The Journal of Pain @thejournalofpain.bsky.social · Sep 4

Original: Opdensteinen, @tanjahechler.bsky.social et al. show that anticipation and provocation of (non-painful) interoceptive sensations elicits fear responses in adolescents with chronic pain

Full: www.jpain.org/article/S152...

The Journal of Pain @thejournalofpain.bsky.social · Sep 3

Original: Ahrensberg et al. complementary and alternative medicine may aid chronic pain management, but further research is needed for safe integration into healthcare systems

Full: www.jpain.org/article/S152...

The Journal of Pain @thejournalofpain.bsky.social · Sep 2

Original: Wang et al. highlight the innovative finding of increased GLYAT levels in DRG neurons of the mice with osteoarthritis pain.

Full: www.jpain.org/article/S152...