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thesquiggles.bsky.social
thesquiggles.bsky.social
@thesquiggles.bsky.social
58 followers 110 following 72 posts
💊Biotech 🎮games 📚literature 🫀medicine.
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Showing up for No Kings Day. Probably one of the chillest protest gatherings I've ever attended.❤️ #nokings #wisconsin #middleton
This is for visibility on why I support the government shut down, because most of us can't afford even more expensive healthcare. I know this topic is polarizing, but it's important to me people know where I stand. These two say it best. #AOC #BernieSanders
We believe healthcare is a right for every American.

But starting today, millions of people will be notified that they are being priced out of their insurance thanks to Republican policies.

Enough is enough. The GOP may shut down the government, but we will stand tall for YOU.
She's a Legend. May her name live on #janegoodall #womenofstem
May her work and name live forever.
#JaneGoodall #janegoodall
The anthropologist was famous for her pioneering research with chimpanzees and her influence on conservation
Reposted by thesquiggles.bsky.social
Excited to share another paper from work I did during my PhD with @trishschulte.bsky.social and @madisonearhart.bsky.social. We looked at how fish embryos respond differently to constant and fluctuating temperatures! 🐟
Atlantic killifish are robust little fish, but now @tblanchard.bsky.social & co reveal that fluctuating temperatures while the embryos are developing in the egg can have beneficial and damaging consequences

journals.biologists.com/jeb/article/...
Bike ride to the coffee shop. A little sweaty but ready to get some work done. #normalday #benignexsistance #happyweekend
My life gives me imposter syndrome. And I mean this in the best way. #Career #Personalgrowth #whoami
Reposted by thesquiggles.bsky.social
Day 8 of #LatineHeritageMonth: WHERE PEACE IS LOST, a space fantasy novel by Cuban-American author Valerie Valdes (@valerievaldes.bsky.social). Kel is just another war refugee in a vast universe--but a reactivated war machine begs a question of her and all of us: What will you do for peace?
Why doesn't the DuckDuckGo browser do tab groups? They are so useful?! Why must I chose between privacy and functionality 😭 #DuckDuckGo #browser #smallproblems
My new favorite show on Netflix is Long Story Short. I think I like it better than BoJack Horseman. What a truly beautiful snapshot of family and humanity. #netflix #longstoryshort #newshow
Crying because I can’t support my favorite Journal company now 😭 This is probably just the beginning of small International sellers suspending shipping to the US #tariffs #shoppingsmall
Signed. Stand with FEMA whistle blowers and dissenters.
On the 20th anniversary of Hurricane Katrina, I signed this letter of support for the FEMA dissenters. Please join me, friends!
The #FEMA36 didn’t stay quiet when lives were on the line. They spoke out & were punished for it.

Now it’s our turn to stand up for them. Sign your support here 👉
www.standupforscience.net/fema-katrina...

thanks @rbreich.bsky.social for amplifying!

#standupforscience #sufs #31daysofaction
The Silk Song release trailer made me tear up. I'm so excited, and it looks so incredible. I can't believe it's finally happening #silksong #teamcherry #letsgo
I just finished What Remains of Edith Finch, and omg what an incredible narritve. A couple of the stories gut punched me so hard I couldn't speak after, I was so
Incredibly sad and moved. #games #edithfinch #amgaming
“Structural, Systemic Problems Cannot Be Solved By Individuals: The Game" Is how I am going to describe DA2 to everyone I meet now.
Out of context, this is by far my favorite thing the copilot AI has said to me.
I just have to say, Confabulation Cascade is a million dollar catch phrase for how vibe coding can fail you 😂
Even Ars who are in the habit of talking up AI tools are struggling with this one. “The agent admitted mistakes” - nope. “Perhaps people shouldn’t use them” - indeed.
I think this is a cool idea for some game types, for sure. I still think that games with a specific narrative vision would suffer however leaving the NPC dialogue to an LLM. My first thought was a game like BG3 with LLM NPCs. I could see that being a mess.
So many interesting biology shares today. Reposting for later reading
TIL two interesting things about horizontal gene transfer (HGT), typically conceptualized as bacterial sex 🧪:

1. It's often driven by mobile (selfish) genetic elements, and therefore might be more akin to infection than sex: cell.com/trends/genet...
Why do mobile genetic elements transfer DNA of their hosts?
The prokaryote world is replete with mobile genetic elements (MGEs) – self-replicating entities that can move within and between their hosts. Many MGEs not only transfer their own DNA to new hosts but...
cell.com
Reposted by thesquiggles.bsky.social
For decades, the only way to make custom DNA in bulk has been phosphoramidite synthesis, a chemical process that can construct nucleic acids up to 350 nucleotides or so in length. Advances in chemical & enzymatic methods has more than doubled that. 🧪 By @carolineseydel.bsky.social @nature.com
Made-to-order DNA goes big: new tech doubles size of custom genetic sequences
Enzyme-based techniques and refinements in organic chemistry ease the generation of extended DNA sequences.
www.nature.com