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Tonny Johnson @tonnyjohnson.bsky.social · Sep 21

Why Eating Windows That Are Too Short or Too Long May Shorten Lifespan.

www.marinbio.com/circadian-nu...

Circadian Nutrition: Why Eating Windows That Are Too Short or Too Long May Shorten Lifespan - Marin Biologic Laboratories

Time-restricted eating (TRE) and other time-based dietary patterns have gained attention for their potential benefits on metabolic health, including improved glucose regulation, better lipid profiles,...

www.marinbio.com

Tonny Johnson @tonnyjohnson.bsky.social · Aug 9

Organoids in the Development of Pharmacokinetics, Pharmacodynamics, and Potency Assays
www.marinbio.com/development-...

#organoids #Pharmacokinetics, #Pharmacodynamics #potencyassays

Development of Pharmacokinetics (PK), Pharmacodynamics (PD) and Potency Assays With Organoids

Revolutionize drug development using advanced cell-based assays with flow cytometry expertise, offering unparalleled organ mimicry and functional complexity.

www.marinbio.com

Tonny Johnson @tonnyjohnson.bsky.social · Aug 9

Next-Generation Cancer Models: Organoids Shaping the Future of Cancer Drug Discovery
www.marinbio.com/next-generat...

#organoids #drugdiscovery #cancer

Next-Generation Cancer Models: Organoids Shaping the Future of Cancer Drug Discovery

Explore transformative organoid technologies for cancer research, advancing drug discovery and development. Learn about diverse organoid applications.

www.marinbio.com

Tonny Johnson @tonnyjohnson.bsky.social · Aug 9

Gene Therapy for Anti-Aging and Longevity: Current Insights, Comparative Strategies, and Future Directions
www.marinbio.com/gene-therapy...

#antiaging #aging #longevity #genetherapy

Gene Therapy for Anti-Aging and Longevity: Current Insights, Comparative Strategies, and Future Directions

Using AAV9 vectors to deliver the secreted isoform of the Klotho gene in wild-type mice, the researchers achieved several significant outcomes. Notably, when treatment was initiated at mid-life (12 mo...

www.marinbio.com

Tonny Johnson @tonnyjohnson.bsky.social · Aug 9

PROTAC Clinical Achievement: New Oral Estrogen Receptor Degrader Shows Promise in Advanced Breast Cancer

www.marinbio.com/protac-clini...

#protac #breastcancer

PROTAC Clinical Achievement: New Oral Estrogen Receptor Degrader Shows Promise in Advanced Breast Cancer

the VERITAC-2 phase 3 trial in patients with ER-positive, HER2-negative advanced breast cancer found that vepdegestrant (ARV-471), an oral PROTAC estrogen receptor degrader, achieved significantly lon...

www.marinbio.com

Tonny Johnson @tonnyjohnson.bsky.social · Aug 9

CAR-NK Cells: A Promising Immunotherapeutic Approach for Breast Cancer Treatment
www.marinbio.com/car-nk-cells...

#cartcells #nkcar #immunotherapy #celltherapy

CAR-NK Cells: A Promising Immunotherapeutic Approach for Breast Cancer Treatment

CAR-NK cells have several advantages over other immunotherapies. They are off-the-shelf, allowing scalable production. Their dual cytotoxic mechanisms, CAR-driven and innate, reduce the risk of antige...

www.marinbio.com

Tonny Johnson @tonnyjohnson.bsky.social · Jun 21

Emerging Trends in Oncolytic Viral Therapy: Innovations from Preclinical to Translational Research
-Highlights from the 2025 AACR Meeting
Link to the news article: www.marinbio.com/emerging-tre...

#onclyticvirus #oncolyticvirotherapy #viraltherapy. #cancertherapy #immunotherapy #cancer

Emerging Trends in Oncolytic Viral Therapy: Innovations from Preclinical to Translational Research

Explore innovative oncolytic virus strategies at AACR 2025. Learn about tumor-selective therapy and immune modulation compared to AAV-based gene therapy.

www.marinbio.com

Tonny Johnson @tonnyjohnson.bsky.social · Jun 2

Cutting-Edge Trends in Gene and Cell Therapy for Diabetes Treatment
#diabetes #type1diabetes #type2diabetes #genetherapy #diabetesgenetherapy

www.marinbio.com/cutting-edge...

Cutting-Edge Trends in Gene and Cell Therapy for Diabetes Treatment

Explore breakthroughs in gene therapy, offering promising diabetes treatments with durable glycemic control and reduced immune rejection.

www.marinbio.com

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Tonny Johnson @tonnyjohnson.bsky.social · Jun 2

Translational Gene Therapy Breakthroughs for Inherited and Acquired Blindness

#blindness #RetinitisPigmentosa #StargardtDisease, #UsherSyndrome #LeberCongenitalAmaurosis #LCA #glaucoma #GeographicAtrophy #MacularDegeneration #genetherapy
www.marinbio.com/from-bench-t...

Translational Gene Therapy Breakthroughs for Inherited and Acquired Blindness

Discover advanced gene therapy strategies for blindness at ASGCT 2025, featuring innovative cell based assays and transformative treatments for inherited vision loss.

www.marinbio.com

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Tonny Johnson @tonnyjohnson.bsky.social · Mar 1

Engineered HSV-1 Oncolytic Virus Strain Offers New Hope for Solid Tumor Therapy
ttps://www.marinbio.com/engineered-oncolytic-virus-strain-offers-new-hope-for-solid-tumor-therapy/

#oncolyticvirus #cancertherapy #herpessimplexvirus #immunotherapy #colorectalcancer #glioma

Engineered Oncolytics Viruses for Solid Tumor Therapy

Discover OncoDelta, a novel oncolytic virus engineered to selectively target and destroy tumors, boosting immune response for effective cancer treatment.

www.marinbio.com

Tonny Johnson @tonnyjohnson.bsky.social · Feb 17

Aspirin for Treating Parkinson’s Disease
www.marinbio.com/when-a-wonde...
#aspirin #parkinsonsdisease #parkinsons #neurodegenerativediseases

Aspirin for Treating Parkinson’s Disease

Explore aspirin's potential in Parkinson’s disease through K63-linked ubiquitination and lysosomal degradation of α-synuclein aggregates.

www.marinbio.com

Tonny Johnson @tonnyjohnson.bsky.social · Feb 17

Aspirin as a PROTAC Antagonist
www.marinbio.com/aspirin-as-a-protac-and-molecular-glue-antagonist-a-hypothetical-consideration-based-on-recent-findings
@ifreecell.bsky.social
@guipap.bsky.social @hartungingo.bsky.social @estableforth.bsky.social
@trendingbrasil.bsky.social

Aspirin as a PROTAC and Molecular Glue Antagonist

Unlock the future of targeted protein degradation with PROTACs & molecular glues in clinical trials. Discover breakthroughs for cancer & more. Learn more!

www.marinbio.com

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Tonny Johnson @tonnyjohnson.bsky.social · Feb 16

Bispecific Antibody Therapy: A New Hope for Treatment-Resistant Follicular Lymphoma
www.marinbio.com/bispecific-a...

#bispecificantibody #lymphoma #immunotherapy #cancer

Novel Bispecific Antibody Treatment for Drug-Resistant Lymphoma

Explore groundbreaking bispecific antibody therapy offering hope for drug-resistant follicular lymphoma patients.

www.marinbio.com

Tonny Johnson @tonnyjohnson.bsky.social · Feb 15

Revolutionizing Glioblastoma Immunotherapy: Engineered T-Cell Therapy to Eradicate Glioblastoma Stem-Like Cells

www.marinbio.com/revolutioniz...

Breakthrough TCR-T Therapy Targets Glioblastoma

Discover innovative TCR-T cell therapy targeting glioblastoma, showing promise in combatting this aggressive cancer. Explore groundbreaking research now.

www.marinbio.com

Tonny Johnson @tonnyjohnson.bsky.social · Feb 15

Breaking the Blood-Brain Barrier (BBB): A Nose-to-Brain Drug Delivery Breakthrough for Treating Neurological Disorders

www.marinbio.com/breaking-the...

Brain Drug Delivery: Overcoming the Blood-Brain Barrier

Explore innovative drug delivery methods for brain disorders using nasal probiotic bacteria, bypassing blood-brain barrier challenges. Discover more!

www.marinbio.com

Tonny Johnson @tonnyjohnson.bsky.social · Feb 15

PROTAC Meets Cell Therapy: Enhancing NK Cell-Based Immunotherapy Through PROTACs

ttps://www.marinbio.com/protacs-meets-cell-therapy-enhancing-nk-cell-based-cancer-immunotherapy-through-targeted-protein-degraders-tpds/

#PROTAC #MolecularGlues #Cancertherapy #Immunotherapy