Trevor Nolan
@trevormnolan.bsky.social
250 followers 270 following 10 posts
Assistant Professor of Biology and Biological Engineering at Caltech. www.trevornolan.science
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trevormnolan.bsky.social
Congrats, Priya! That's amazing and very well deserved. Looking forward to the many exciting things you'll do there!
Reposted by Trevor Nolan
Reposted by Trevor Nolan
bipinpandey.bsky.social
Thrilled to see our work now online @nature.com
This study reveals how individual root cells sense and respond to real, compacted soil environments.
www.nature.com/articles/s41...

beautiful spatial transcritomics of rice root in gel & soil conditions and huge credit to Mingyuan and colleagues.
Reposted by Trevor Nolan
bradylabs.bsky.social
We have a postdoc position that just opened up in the Brady lab on reprogramming tomato root system architecture in response to changes in nutrient availability - please consider applying! recruit.ucdavis.edu/JPF07095
Postdoctoral Researcher- Brady Lab
University of California, Davis is hiring. Apply now!
recruit.ucdavis.edu
Reposted by Trevor Nolan
aribidopsis.bsky.social
(1/17) We are excited to share the Ashraf and Gallagher labs collaboration on cell cycle regulation during environmental stress recovery in Arabidopsis, Brachypodium, and ryegrass.
biorxiv-plants.bsky.social
Cell cycle follows pause and play mechanism in environment stress recovery in diverse plant species https://www.biorxiv.org/content/10.1101/2025.04.02.646900v1
trevormnolan.bsky.social
Congrats, all! This is fascinating work.
Reposted by Trevor Nolan
jennyrussinova.bsky.social
🌱 When a root cell undergoes symmetric division, are the daughter cells actually identical? By combining live-cell imaging and scRNAseq we discovered a new cell state with uneven BR activity. Read our full paper in Cell: doi.org/10.1016/j.ce... @nvukas.bsky.social @trevormnolan.bsky.social
trevormnolan.bsky.social
See our full thread is here for more details bsky.app/profile/jenn...
jennyrussinova.bsky.social
🌱 When a root cell undergoes symmetric division, are the daughter cells actually identical? By combining live-cell imaging and scRNAseq we discovered a new cell state with uneven BR activity. Read our full paper in Cell: doi.org/10.1016/j.ce... @nvukas.bsky.social @trevormnolan.bsky.social
trevormnolan.bsky.social
We dedicate this study to my postdoctoral mentor Philip Benfey—a visionary in plant developmental biology whose groundbreaking contributions and unwavering mentorship enabled so many scientific careers, including mine.
trevormnolan.bsky.social
This project was led by @nvukas.bsky.social with key contributions from Che-Wei Hsu, and several research groups, including The Russinova and Nolan labs. Many thanks to all our coauthors! @emmanuellebayer.bsky.social @rachelmshahan.bsky.social
trevormnolan.bsky.social
🖥️ Dive into our interactive atlas to explore these dynamics and your favorite genes in detail: nolanlab.shinyapps.io/arvex
ARVEX
Legends
nolanlab.shinyapps.io
trevormnolan.bsky.social
📸 Live imaging provided the answer: immediately after division, daughter cells diverge into distinct roles. One cell specializes in signaling while the other boosts biosynthesis, circumventing feedback inhibition.
trevormnolan.bsky.social
🧬 Single-cell analysis showed brassinosteroid signaling peaks during G1 phase. Surprisingly, we also observed increased expression of brassinosteroid biosynthesis gene DWF4 at the same stage. How is this possible, given known feedback inhibition?
trevormnolan.bsky.social
🔬 Our lab developed a detailed single-cell cell-cycle reference atlas—led by efforts from Che-Wei Hsu and phase markers from Laura Lee—allowing us to precisely track hormone signaling dynamics across the cell cycle
trevormnolan.bsky.social
🌱 Thrilled to see our latest collaborative work with @jennyrussinova.bsky.social @nvukas.bsky.social published in Cell! By combining single-cell RNA-seq and live imaging, we uncovered previously hidden brassinosteroid signaling states and their role in optimizing root growth. doi.org/10.1016/j.ce...