Lightnews — Scholar-powered news

USCAP @uscap.org · 19h

This is happening in just over an hour on Facebook Live: facebook.com/TheUSCAP

See you there!

#PathSky

USCAP @uscap.org · 3d

Don't miss this free Facebook Live broadcast from the Palm Springs Interactive Center! Thursday, Oct. 9 10:45 AM - 12:15 PM Pacific. Dr. Nicole Panarelli will discuss Esophageal Carcinoma and Precursors.

facebook.com/TheUSCAP

#PathSky

USCAP @uscap.org · 3d

Don't miss this free Facebook Live broadcast from the Palm Springs Interactive Center! Thursday, Oct. 9 10:45 AM - 12:15 PM Pacific. Dr. Nicole Panarelli will discuss Esophageal Carcinoma and Precursors.

facebook.com/TheUSCAP

#PathSky

USCAP @uscap.org · 6d

Discussion 2: This is always secondary to something external to the lung, usually in the mediastinum or in the heart. In this case, being from St. Louis, he probably had histoplasmosis and developed sclerosing mediastinitis which led pulmonary vein compression and then venous infarction in the lung.

USCAP @uscap.org · 6d

Discussion 1: The lung shows an infarct with minimal blood closely associated with a pulmonary vein. This is characteristic of a venous (as opposed to arterial) infarct. This is always secondary to something external to the lung, usually in the mediastinum or in the heart.

1

USCAP @uscap.org · 6d

Diagnosis: Venous infarction in the setting of mediastinal disease (probably sclerosing mediastinitis due to histoplasmosis).

1

USCAP @uscap.org · 6d

Imaging showed lower lobe pulmonary infiltrates and mediastinal soft tissue expansion associated with flecks of calcification and compression of pulmonary veins. He underwent lung biopsy. Image B is elastic trichrome stain.

1

USCAP @uscap.org · 6d

Dr. Henry D. Tazelaar shared a case in advance of our November Thorax Revisited course (my.uscap.org/app/program/...) Join him in Palm Springs to discuss in person!

#PathSky

History: A 54 year old man from St. Louis presented with cough and hemoptysis.

1 1

USCAP @uscap.org · 7d

It's the weekend-before-abstracts-are-due and we need you to remember two very important things:

1. You've got this
2. Music might help: open.spotify.com/playlist/5EI...

#PathSky #USCAP2026 #YouGotThis

You've Got This - Abstract Writing 2026

open.spotify.com

2 2

USCAP @uscap.org · 8d

Free CME: Mastering the Complexities of EoE Diagnosis is now available in our eLearning Hub.
elearning.uscap.org/courses/113129

USCAP @uscap.org · 13d

Calling pathologists whose research, publications, and service, have shaped the field. Applications for the 2026 Honors Awards close in just one month!!

Each year,these awards celebrate excellence across our profession. Submit now for your chance to be honored.

uscap.org/honors

#PathSky

1

USCAP @uscap.org · 17d

Description 2: and small focus of very well differentiated glands invading through the muscularis mucosae with associated early desmoplastic stromal reaction.

USCAP @uscap.org · 17d

Description 1: Lesion (polyp) with non-dysplastic serrated epithelium extending to architecturally distorted crypts (horizontally dilated, flat, anchor- or L/boot-shaped)

1

USCAP @uscap.org · 17d

Diagnosis: Sessile serrated lesion (SSL) with small focus of well-differentiated adenocarcinoma.

1

USCAP @uscap.org · 17d

Sample case from course director Alexandros D. Polydorides.

Clinical history: 45 M for screening colonoscopy, with a large “flat” polyp in the ascending colon removed by EMR.

1

USCAP @uscap.org · 17d

my.uscap.org/app/program/... During this hands-on case-based course, we'll review the newest diagnostic & classification updates of tubular GI neoplasms, with changes coming up in the new WHO blue book to be published in early 2026, with some of its actual editors & authors!
#pathsky

1 1

USCAP @uscap.org · 17d

Description 2: and small focus of very well differentiated glands invading through the muscularis mucosae with associated early desmoplastic stromal reaction.

USCAP @uscap.org · 17d

Description 1: Lesion (polyp) with non-dysplastic serrated epithelium extending to architecturally distorted crypts (horizontally dilated, flat, anchor- or L/boot-shaped)

1

USCAP @uscap.org · 17d

Diagnosis: Sessile serrated lesion (SSL) with small focus of well-differentiated adenocarcinoma.

1

USCAP @uscap.org · 21d

Consider this your gentle reminder that the deadline for abstract submissions for our 2026 Annual Meeting is Tuesday, Oct. 7 at 11 am Pacific.

uscap.org/abstracts

#USCAP2026 #MakingConnections

USCAP @uscap.org · Sep 4

Reference 2:
Angirekula M et al. CD117, BAP1, MTAP, and TdT Is a Useful Immunohistochemical Panel to Distinguish Thymoma from Thymic Carcinoma. Cancers (Basel). 2022;14(9):2299.

1

USCAP @uscap.org · Sep 4

Reference 1:
WHO Classification of Tumours Editorial Board. Thoracic tumours. Lyon (France): International Agency for Research on Cancer; 2021. (WHO classification of tumours series, 5th ed.; vol. 5). publications.iarc.fr/595.

1 1

USCAP @uscap.org · Sep 4

The differential diagnosis includes carcinoma. The absence of desmoplasia, the presence of perivascular spaces, and, while not entirely sensitive, the lack of expression of CD5 and CD117 argue against carcinoma and are further suggestive of thymoma.

1

USCAP @uscap.org · Sep 4

Although the morphological features are suggestive of a B3 thymoma, thymomas are usually not subtyped on small biopsies because of their potential heterogeneity. Given that the patient had multiple pleural-based nodules, this may represent a thymoma with pleural metastases (“implants”).

1

USCAP @uscap.org · Sep 4

No increased mitotic activity or necrosis are apparent. The morphologic features are suggestive of thymoma which is further supported by the diffuse expression of p40 (B) and pankeratin (not shown) by the neoplastic cells and expression of TdT (D) by thymocytes.

1

USCAP @uscap.org · Sep 4

Sheets of polygonal tumor cells (A) w/focal clusters & scattered small lymphocytes (C) & focal band-like fibrosis (low power picture in case stem) are seen. The tumor cells have a fair amount of cytoplasm and large nuclei some with conspicuous nucleoli. Perivascular spaces are present (A, arrow).

1