John Vandermosten
vanjohn10.bsky.social
John Vandermosten
@vanjohn10.bsky.social
Life Sciences, Analyst, Media Operations, Investor Awareness
Owner of Unboxing Biotech, a channel that features life sciences executives and their companies.
TuHURA CEO Dr James Bianco explains how the delta opioid receptor (DOR) works and the way in which it affects immune system response
#$HURA
#MDSCs #ImmunoOncology #CancerResearch #CancerTreatment #Oncology
youtube.com/shorts/eE8x8...
How Does the Delta Opioid Receptor Work?
YouTube video by Unboxing Biotech
youtube.com
January 19, 2026 at 5:36 PM
After a vaccine receives approval, there are still hurdles to overcome before administration. We look at some of the new technologies including portable refrigerators, new battery technology & drones. GeoVax CEO David Dodd shares his thoughts on the topic. #$GOVX
youtu.be/10ylZjTHrNo
Vaccine Distribution
YouTube video by Unboxing Biotech
youtu.be
January 19, 2026 at 12:16 AM
Dr Bianco introduces TuHURA’s Immune Modulating ADCs which link a VISTA inhibitor to a delta opioid receptor inhibitor to target the tumor microenvironment rather than the tumor itself
#$HURA
#TumorMicroenvironment #ImmunoOncology #MDSCs #MyeloidCells #VISTA #Oncology #ADC youtube.com/shorts/jfTnJ...
Immune Modulating ADCs
YouTube video by Unboxing Biotech
youtube.com
January 16, 2026 at 2:56 PM
GeoVax CEO David Dodd attended several conferences in Europe in 2H25 & heard concerns from stakeholders regarding a resurgence in previously considered eradicated viruses. We review measles, polio & whooping cough.
$GOVX
#biotech #biotechnology #science #GeoVax #Vaccines
youtu.be/QMri80C_A8s
Three Re emerging Pathogens
YouTube video by Unboxing Biotech
youtu.be
January 15, 2026 at 3:37 PM
Jazz Pharma sells FDA's Priority Review Voucher to undisclosed buyer for $200mm. The PRV was related to rare pediatric disease drug Modeyso.
PRV prices have ranged from $68-$350mm over the last 12 years.
$JAZZ
www.firstwordpharma.com/story/7064821
www.firstwordpharma.com
January 15, 2026 at 1:49 PM
TuHURA Bio developed an SPA guided by the FDA's Project Frontrunner to advance promising therapies. CEO Bianco explains the process & the resulting efficient trial design that allows for both accelerated & full approval. $HURA
#Bioscience #LifeSciences #Oncology youtube.com/shorts/lcHe9...
IFx 2 0 Trial Design
YouTube video by Unboxing Biotech
youtube.com
January 14, 2026 at 4:45 PM
$LGND Ligand shares down 11% today on a delay in Travere's Filspari approval timeline. FDA requesting more info for the FSGS indication right before PDUFA date. At best it is a delay. Our model and valuation do not include a contribution from FSGS. Biospace reporting www.biospace.com/press-releas...
Travere Therapeutics Provides Corporate Update and 2026 Outlook
www.biospace.com
January 13, 2026 at 3:51 PM
A lyophilized version of the smallpox vaccine was recently approved by the FDA. GeoVax also expects to have a freeze dried version of the vaccine after approval. This formulation is useful in developing regions & for storage. CEO David Dodd shares his thoughts.
$GOVX
youtu.be/KTjMXmpZoK0
Lyophilized Mpox Vaccine
YouTube video by Unboxing Biotech
youtu.be
January 13, 2026 at 2:27 PM
Lexaria CEO pens annual shareholder letter
*progress on GLP1 studies
~DHT shows improved adverse events
~effective in market with few oral options
*2026 priority remains GLP1 & MTA partner relationship
*designing next GLP1 study
*other biz dev in place
$LEXX
lexariabioscience.com/2026/01/12/l...
Lexaria Releases Annual Letter from the CEO - Lexaria Bioscience
KELOWNA, BC / ACCESS Newswire / January 12, 2026 / Lexaria Bioscience Corp. (Nasdaq:LEXX)(Nasdaq:LEXXW), (the “Company” or “Lexaria”), a global innovator in drug delivery platforms is pleased to provi...
lexariabioscience.com
January 12, 2026 at 3:27 PM
Achieve Life Sciences appoints Dr Mark Rubinstein as permanent Chief Medical Officer. Prior to $ACHV, he was Head of Medical Affairs at Blip where he led a strategy to support smoking & vaping cessation.
finance.yahoo.com/news/achieve...
Achieve Life Sciences Confirms Promotion of Dr. Mark Rubinstein to Chief Medical Officer
Experienced medical executive advances to permanent role following successful leadership as Interim CMOSEATTLE and VANCOUVER, British Columbia, Jan. 12, 2026 (GLOBE NEWSWIRE) -- Achieve Life Sciences,...
finance.yahoo.com
January 12, 2026 at 3:18 PM
Tuhura Biosciences CEO Dr Bianco explains the delta opioid receptor's mechanism & how its inhibition can allow the immune system and other agents to fight cancer. $HURA
#LifeSciences #Oncology
youtube.com/shorts/lWAhB...
Immune Tolerance and the Delta Opioid Receptor
YouTube video by Unboxing Biotech
youtube.com
January 12, 2026 at 1:45 PM
Radiopharm Theranostics increases ownership in Radiopharm Ventures to 87.5%-a JV with MD Anderson for advancing Betabart (RV01). The Lu-177, B7H3 targeting antibody is the subject of a Ph1 study in solid tumors.
$RADX
finance.yahoo.com/news/rad-inc...
RAD Increases Ownership in Radiopharm Ventures to 87.5%
Radiopharm Ventures, LLC, is a joint venture created in 2022 between MD Anderson Cancer Center and Radiopharm TheranosticsLeading candidate Betabart, a monoclonal antibody targeting B7H3, has received...
finance.yahoo.com
January 12, 2026 at 1:18 PM
Dr Bianco explains the mechanism behind immunosuppression which is impacted by FOXP3's control of Tregs. TuHURA has identified the Delta Opioid Receptor as the switch that can modulate immune cell function. $HURA
youtube.com/shorts/ETegB...
Delta Opioid Receptor Role in Immunosuppression
YouTube video by Unboxing Biotech
youtube.com
January 10, 2026 at 6:00 PM
Where is the US government willing to invest in the biopharma space? GeoVax Labs CEO David A. Dodd explains which technologies make the most sense to support with funding.
$GOVX
www.youtube.com/watch?v=tOgs...
Legislators & Domestic Vaccine Manufacture
YouTube video by Unboxing Biotech
www.youtube.com
January 9, 2026 at 2:42 PM
Reviva Pharmaceuticals publishes RECOVER vocal biomarker data in Biological Psychiatry
*A Single, Interpretable Vocal Biomarker for Enriching Antipsychotic Clinical Trials
www.biologicalpsychiatryjournal.com/article/S000...
$RVPH
finance.yahoo.com/news/reviva-...
A single, interpretable vocal biomarker for enriching antipsychotic clinical trials
Speech latency, an objective measure of verbal response time, is sensitive to cognitive, social, and motivational factors, and can be measured using recordings of psychiatric interviews. Emerging evid...
www.biologicalpsychiatryjournal.com
January 8, 2026 at 7:48 PM
CEO Dr Bianco shares TuHURA's work with the #FDA's Oncology Center of Excellence to construct a trial to satisfy requirements for accelerated & full approval of IFx-2.0 in Merkel Cell Carcinoma
$HURA
#TuhuraBio #Bioscience #LifeSciences #Oncology #TargetedTherapies
youtube.com/shorts/eeS09...
IFx 2.0 Trial Design
YouTube video by Unboxing Biotech
youtube.com
January 8, 2026 at 7:27 PM
The Delta Opioid Receptor & Nobel Prize Discovery:
TuHURA Biosciences CEO Dr James Bianco joins us to talk about work $HURA has done to better understand the delta opioid receptor. Findings tie into the 2025 #NobelPrize in medicine that made discoveries in peripheral immune tolerance. #oncology
January 7, 2026 at 9:31 PM
Azitra's COO Travis Whitfill to present at Biotech Showcase next week.
*13Jan26
*Hilton SFO Union Square
$AZTR
finance.yahoo.com/news/azitra-...
Azitra, Inc. to Present at Biotech Showcase Alongside the J.P. Morgan Annual Healthcare Conference
Azitra, Inc. ("Azitra") (NYSE American: AZTR), a clinical stage biopharmaceutical company focused on developing innovative therapies for precision dermatology, today announced that it will present at ...
finance.yahoo.com
January 7, 2026 at 1:35 PM
Protalix CEO Dror Bashan pens letter to stockholders emphasizing:
*Development
~Ph2 PRX115
~Renal pipeline-PRX119
~Secarna OligoCreator
*Chiesi, Elfabrio & CHMP flexible dosing
*Dec'25 BioMarin/Amicus Galafold acq
*Elelyso
$PLX
ir.protalix.com/news-release...
Protalix BioTherapeutics Letter to Stockholders | Protalix BioTherapeutics
ir.protalix.com
January 5, 2026 at 2:20 PM
@lantheus.bsky.social closes SPECT business sale to SHINE Technologies
*Includes Technelite, Neurolite, Xenon Gas & Cardiolite
$LNTH
finance.yahoo.com/news/lantheu...
Lantheus Announces Closing of SPECT Business Sale to SHINE Technologies
BEDFORD, Mass., Jan. 02, 2026 (GLOBE NEWSWIRE) -- Lantheus Holdings, Inc. (“Lantheus” or the “Company”) (NASDAQ: LNTH), the leading radiopharmaceutical-focused company dedicated to helping clinicians ...
finance.yahoo.com
January 2, 2026 at 2:13 PM
More Ph1b data from Lexaria for GLP-1 agonist study:
*Rough parity reported between the arms for glucose, cholestrol & LDLs.
*DHT-CBD showed reduced blood pressure
This + other data suggest the best route forward to be DHT-Rybelsus vs DHT-semaglutide.
$LEXX
lexariabioscience.com/2025/12/30/l...
Lexaria Releases Additional Results from its Successful Phase 1b Study GLP-1-H24-4 - Lexaria Bioscience
KELOWNA, BC / ACCESS Newswire / December 30, 2025 / Lexaria Bioscience Corp. (NASDAQ:LEXX)(NASDAQ:LEXXW) (the “Company” or “Lexaria”), a global innovator in drug delivery platforms, provides the follo...
lexariabioscience.com
December 31, 2025 at 2:35 PM
We initiated on Cardiff Oncology with an $8.50 price target.
youtu.be/_pV9tsv2h8Y
See our report at the link below:
s27.q4cdn.com/906368049/fi...
#CardiffOncology #CRDF #Biotech #Oncology
Zacks Initiation on Cardiff Oncology (CRDF)
YouTube video by Unboxing Biotech
youtu.be
December 24, 2025 at 4:47 PM
#ICYMI, here is the 2nd installment of a conversation with Trinity Capital's Rob Lake who explores post-COVID performance in the life sciences, acknowledges the patent cliff & reviews M&A trends.
$TRIN
youtu.be/be1JI6m7AsU
Conversation with Trinity Capital's Life Science Lead Rob Lake #2
YouTube video by Unboxing Biotech
youtu.be
December 22, 2025 at 4:47 PM
#ICYMI, we speak with Trinity Capital's Life Science Lead Rob Lake in part 1 of a two part series. We look at some of the ways private capital can be used to help developing companies achieve milestones and limit dilution.
$TRIN
www.youtube.com/watch?v=Dx0E...
Conversation with Trinity Capitals Life Science Lead Rob Lake #1
YouTube video by Unboxing Biotech
www.youtube.com
December 19, 2025 at 2:45 PM
Athira Pharma to acquire lasofoxifene in Ph3 development with funding participation by Ligand Pharma. $LGND has an agreement to receive milestones & tiered royalty of 6-10% on future next sales.
Drug treats ESR1-mutant breast cancer.
$ATHA
investors.athira.com/news-release...
Athira Pharma Announces Exclusive License to Lasofoxifene Phase 3 Development Program for Metastatic Breast Cancer Candidate and a Financing for up to $236 Million | Athira Pharma
Phase 3 Development Program of Novel Selective Estrogen Receptor Modulator (SERM) Represents Potential Multi-Billion Dollar Opportunity as Treatment Option for Patients with ESR1-Mutations Financing C...
investors.athira.com
December 18, 2025 at 10:45 PM