vreedecompchem.bsky.social
@vreedecompchem.bsky.social
Reposted
April 25, 2025 at 8:09 AM
Reposted
Jocelyne Vreede is a professor at University of Amsterdam, using molecular simulation to study nucleic acids in atomistic detail. She will host 2 students within MeChaNiSM to characterise how modified bases and small molecules affect nucleic acid structure and dynamics. @vreedecompchem.bsky.social
June 17, 2025 at 7:55 AM
When a protein binds to DNA, it can locally change the DNA. We characterized such a process with molecular simulation and spectroscopy in our recent publication. pubs.acs.org/doi/10.1021/...
Adaptation of DNA to Protein Binding Revealed by Spectroscopy and Molecular Simulation
DNA demonstrates remarkable structural diversity, transitioning between conformations such as B-DNA and A-DNA under specific environmental or protein-binding conditions. These transitions are relevant...
pubs.acs.org
June 5, 2025 at 5:53 AM