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walshdls.bsky.social
Martin Walsh
@walshdls.bsky.social
1.5K followers 450 following 180 posts
Structural Biologist at Diamond Light Source UK. Interests mainly respiratory bacterial and viral pathogens, AMR and methods developments to leverage synchrotron radiation and electron imaging. Synergetic imaging is yer only man. Views definitely my own
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walshdls.bsky.social
Martin Walsh @walshdls.bsky.social · Aug 4
krios 1 @diamondlightsource.bsky.social celebrated 10 years of user operations last week - many people thought we were mad to plonk it down in this spot in the synchrotron …but its still there as we ended up with a lot more in a very small space of time !
Titan krios I (a 300 KeV Cryo transmission electron microscope) with its 10 yr birthday hat in the experimental hall of Diamond Light Source.
Reposted by Martin Walsh
janinebrunner.bsky.social
MISO: microfluidic protein isolation enables single-particle cryo-EM structure determination from a single cell colony.

Or from a single dish of HEK cell culture in the case of two membrane proteins.

Out in Nature Methods now! lnkd.in/gpyBSceg

Wonderful collaboration with the Efremov lab.
November 14, 2025 at 6:38 PM
Reposted by Martin Walsh
coastclark.bsky.social
Goodday Bluesky

The Day of the Dead (1924) by Diego Rivera
November 2, 2025 at 6:03 PM
Reposted by Martin Walsh
sykhalid.bsky.social
Really interesting interview. @timcoulson.bsky.social and I were also fortunate to chat with David Baker on our podcast which you can catch here: Science Of The Times EP7 Pt2 - Interview with 2024 Nobel Prize winner for Chemistry David Baker
youtu.be/jShxgJ3XrWA
November 2, 2025 at 6:24 PM
Reposted by Martin Walsh
rcsbpdb.bsky.social
AI in Protein Design: Hype vs. Reality Explained by David Baker
In this GEN interview, he emphasizes that designing new proteins from scratch is now a reality. Whether AI transforms medicine will require improving our understanding of biology's complexity
AI in Protein Design: Hype vs. Reality Explained by David Baker
In this GEN interview, Nobel Laureate David Baker, PhD, emphasizes that designing proteins from scratch is reality and unpacks what's needed for AI to transform medicine.
www.genengnews.com
November 2, 2025 at 5:34 PM
walshdls.bsky.social
Watching us open on sky sport’s … paying for the day for the first time EVER ;-) …there are adverts and the commentary is uht milk level … bbc Wimbledon coverage superb and value for money and impeccable…just saying …
September 7, 2025 at 7:25 PM
walshdls.bsky.social
www.rollingstone.com/culture/cult... …bill and tes meets sam
Behind the Scenes of Alex Winter and Keanu Reeves' 'Waiting for Godot'
Jamie Lloyd's production of 'Waiting for Godot' stars Alex Winter and Keanu Reeves of 'Bill and Ted' — and is soon opening on Broadway.
www.rollingstone.com
September 6, 2025 at 12:43 PM
Reposted by Martin Walsh
sykhalid.bsky.social
Awesome work!
oxfordbiochemistry.bsky.social Oxford Biochemistry @oxfordbiochemistry.bsky.social · Aug 22
Read the full story here: 📣Breakthrough discovery reveals new gene linked to chronic pain ➡️ bit.ly/202508_newst...
Cryo-Em structure of the SLC45A4 polyamine transporter depicted by a substantial yellow and green area, a purple mid-section, punctuated with turquoise and with the top third of the whole surrounded by a transparent 'membrane'-like structure
August 22, 2025 at 3:51 PM
walshdls.bsky.social
The boys are back in town ;-)
August 18, 2025 at 7:08 PM
Reposted by Martin Walsh
sykhalid.bsky.social
Carol Robinson on Desert Island Discs - have a listen friends: www.bbc.co.uk/sounds/play/...
An inspirational scientist & friend. An example of combining scientific excellence, courage, hard work and really importantly; kindness. (Yes I’m biased, but it’s true nevertheless)
@kavlioxford.bsky.social
Desert Island Discs - Professor Dame Carol Robinson, scientist - BBC Sounds
Dame Carol Robinson, scientist, shares the soundtrack of her life with Lauren Laverne.
www.bbc.co.uk
August 10, 2025 at 10:40 AM
walshdls.bsky.social
Continuing the theme of venue ceilings (admittedly its had poor uptake and i think no one else has succumb to this potentially riveting trend) but as the hotel carpet at this event is not going to impress @scurry.bsky.social i submit this interesting (if i do say so myself) ceiling venue …
Ceiling of venue hosting the final ASAP all hands meeting somewhere in Europe
August 18, 2025 at 6:23 PM
Reposted by Martin Walsh
irishtimes.com
Mary Robinson urges states to act decisively to stop Gaza’s ‘unfolding genocide’
Mary Robinson urges states to act decisively to stop Gaza’s ‘unfolding genocide’
Elders group urge targeted sanctions on Israeli prime minister and security cabinet
www.irishtimes.com
August 12, 2025 at 2:07 PM
walshdls.bsky.social
krios 1 @diamondlightsource.bsky.social celebrated 10 years of user operations last week - many people thought we were mad to plonk it down in this spot in the synchrotron …but its still there as we ended up with a lot more in a very small space of time !
Titan krios I (a 300 KeV Cryo transmission electron microscope) with its 10 yr birthday hat in the experimental hall of Diamond Light Source.
August 4, 2025 at 7:50 AM
Reposted by Martin Walsh
pdbeurope.bsky.social
🚀 Macromolecule structures have been front & center at #ISMBECCB2025 in Liverpool -- the world’s largest #bioinformatics meeting!

🗝️ Keynotes:
www.iscb.org/ismbeccb2025...

🧬More strucurtal bionformatics / computational biology talks, #3DSIG stream:
www.iscb.org/ismbeccb2025...

@3dsig.bsky.social
July 24, 2025 at 11:34 AM
Reposted by Martin Walsh
keithcollantine.bsky.social
A tribute parade for the late Eddie Jordan will take place at Silverstone today.

Many of his team's cars are here, from the first to one of the last (looking particularly odd here due to its absence of nose, Pirelli tyres and lumpy engine cover to accommodate a change of motor).

#F1
July 5, 2025 at 7:22 AM
walshdls.bsky.social
Looking forward to a day of science from our Wellcome Phd programme coordinated by @oxfordbiochemistry.bsky.social @diamondlightsource.bsky.social and the Rosalind Franklin Institute
Merton College Oxford
June 25, 2025 at 7:55 AM
walshdls.bsky.social
This is exciting! www.diamond.ac.uk/Home/News/La... @instruct-eric.bsky.social @fragment-screen.bsky.social @ukri.org @wellcometrust.bsky.social @cancerresearchuk.org
Diamond will host a pioneering AI-driven drug discovery consortium - - Diamond Light Source
New consortium OpenBind will make the UK a world-leader in drug innovation and advancement
www.diamond.ac.uk
June 11, 2025 at 1:01 PM
Reposted by Martin Walsh
irishlittimes.bsky.social
Paul Durcan obituary: Being a poet was all consuming for him www.irishtimes.com/obituaries/2...
Paul Durcan obituary: Being a poet was all consuming for him
Being a poet was all consuming for him. His main pursuit in life, it defined his everyday interactions
www.irishtimes.com
May 23, 2025 at 2:45 PM
walshdls.bsky.social
bbc.com/news/article...
Oxfordshire clock still keeping village on time after 500 years
The timepiece is believed to be one of the oldest clocks in Britain still in its original location.
bbc.com
May 28, 2025 at 6:25 PM
walshdls.bsky.social
Cool location for ringfort!
aidanosullivan.bsky.social Aidan O'Sullivan @aidanosullivan.bsky.social · May 10
Reconstruction of early medieval cashel at Cahercommaun near Kilnaboy, the Burren, Co Clare (by Conor McDermott, based on photo by National Monuments Service and other photoshopped images of houses, cattle, crops and landscape) This is what we think one early medieval ringfort might have looked like
May 10, 2025 at 5:56 PM
Reposted by Martin Walsh
bylinesnetwork.co.uk
Some Welsh contributions to railway history – part two

Wales has a little-known yet incredible history in locomotion. This Railway 200 commemorative year is a great time to make Welsh achievements better known

✍️ Peter Brown

@bylines.cymru
Some Welsh contributions to railway history – part two
Wales has a little-known yet incredible history in locomotion. This Railway 200 commemorative year is a great time to make Welsh achievements better known
bylines.cymru
May 10, 2025 at 1:55 PM
Reposted by Martin Walsh
scurry.bsky.social
Good summary of the state of play for Starmer’s underwhelming government from @iandunt.bsky.social
open.substack.com/pub/iandunt/...
Screenshot from article reads: In every case, the government is typified by a lack of confidence in communication. It is unwilling to lead. It is unprepared to make the argument. It does not have the courage to state clearly what is happening, what it wants and how it will get there. Instead, it operates in the background, saying whatever it thinks necessary to secure goals which you can vaguely discern by virtue of unrelated actions. This is why we're all so confused. Sometimes you wake up and read what they have to say about Trump, or see how they will decimate our university sector to reduce immigration numbers, and you feel the anger rise up in you. Sometimes you recognise what they're achieving, on the hush-hush, and convince yourself that they're playing some ingenious game you seem to have misunderstood. It is really very hard to be governed in this way. It is emotionally baffling. The government does good things and bad things, but this approach to government is disastrous. It's democratically unsound for a party to persistently say one thing and do another, as if governing by subtext. It prevents voter scrutiny and is fundamentally duplicitous. It isn't even effective, because it alienates those who like what you're doing and confuses those who don't. You can see that now. Remainers distrust Starmer as much as Leavers do. No-one is happy.
May 10, 2025 at 5:44 PM
walshdls.bsky.social
Lovely morning in Abingdon
Abingdon-on-Thames
May 7, 2025 at 9:40 AM
walshdls.bsky.social
Just finished an excellent midterm review of our fragment screen project funded by Horizon Europe (thanks to everyone and the reviewers and our project coordinator for constructive feedback) @fragment-screen.bsky.social @instruct-eric.bsky.social @diamondlightsource.bsky.social
May 6, 2025 at 3:20 PM
Reposted by Martin Walsh
fragment-screen.bsky.social
Missed any of the Fragment-Screen webinars with @instruct-eric.bsky.social?

Take a look at them here, with talks from @ceitec.eu, @ebi.embl.org, IBM Research and FFULisboa!

fragmentscreen.org/news-and-eve...
April 23, 2025 at 9:04 AM
walshdls.bsky.social
Hope everyone who made it enjoyed the 3 days of science and networking! We even had nice weather!
EMCC Nottingham - venue for the 2025 Joint BCI (eBIC & B24) user meeting and CCP-EM spring symposium
April 28, 2025 at 1:33 PM