Water Me Loan 64 🍉🐻❄️🐾
@watermeloan64.bsky.social
Silly Samoyed Doggo! (Known for @invertedplanet.bsky.social!)
Age: 23
Nintendo Switch: SW-6536-5413-8120
Discord: WaterMeLoan64#6657
Xbox: WaterMeLoan1072
My LinkTree: https://linktr.ee/watermeloan64
PFP by @fireiscold45.bsky.social
Age: 23
Nintendo Switch: SW-6536-5413-8120
Discord: WaterMeLoan64#6657
Xbox: WaterMeLoan1072
My LinkTree: https://linktr.ee/watermeloan64
PFP by @fireiscold45.bsky.social
Pinned
Royal Tigress Productions, Scratch Animation,and Fruit Salad Animation proudly present THERA: THE INVERTED PLANET!
Kickstarter campaign will be launching in a few days!
Kickstarter campaign will be launching in a few days!
Reposted by Water Me Loan 64 🍉🐻❄️🐾
another new deogie here! tinyview.com/deogie/2025/...
November 25, 2025 at 10:21 PM
another new deogie here! tinyview.com/deogie/2025/...
Reposted by Water Me Loan 64 🍉🐻❄️🐾
Instead of utilizing chemicals, future treatments might bring small, guided particles directly to the microbes that cause harm. This approach promises more precise medicine with fewer side effects.
November 26, 2025 at 6:15 PM
Instead of utilizing chemicals, future treatments might bring small, guided particles directly to the microbes that cause harm. This approach promises more precise medicine with fewer side effects.
Reposted by Water Me Loan 64 🍉🐻❄️🐾
for different infections rather than relying on one size fits all drugs. At a larger scale, the study shows how nanotechnology and glycochemistry can work together.
November 26, 2025 at 5:17 PM
for different infections rather than relying on one size fits all drugs. At a larger scale, the study shows how nanotechnology and glycochemistry can work together.
Reposted by Water Me Loan 64 🍉🐻❄️🐾
shorter hospital stay, fewer complications and a better chance of recovery. For researchers, the work offers a modular platform. By changing the sugars or peptides, teams could design versions that target other bacteria or even fungi. That flexibility may speed the development of custom therapies
November 26, 2025 at 5:17 PM
shorter hospital stay, fewer complications and a better chance of recovery. For researchers, the work offers a modular platform. By changing the sugars or peptides, teams could design versions that target other bacteria or even fungi. That flexibility may speed the development of custom therapies
Reposted by Water Me Loan 64 🍉🐻❄️🐾
device related infections are treated. If the technology succeeds in animals and clinical trials, it could reduce the need for high dose broad spectrum antibiotics. That would help preserve existing drugs and slow the spread of resistance. For someone in intensive care, that shift could mean a
November 26, 2025 at 5:16 PM
device related infections are treated. If the technology succeeds in animals and clinical trials, it could reduce the need for high dose broad spectrum antibiotics. That would help preserve existing drugs and slow the spread of resistance. For someone in intensive care, that shift could mean a
Reposted by Water Me Loan 64 🍉🐻❄️🐾
superbugs. As for practical implications, for patients and clinicians, this research points to a fresh way to fight infections that no longer respond well to antibiotics. A nanogel that can home in on bacteria, break through biofilms and spare healthy cells could change how stubborn lung, wound and
November 26, 2025 at 5:16 PM
superbugs. As for practical implications, for patients and clinicians, this research points to a fresh way to fight infections that no longer respond well to antibiotics. A nanogel that can home in on bacteria, break through biofilms and spare healthy cells could change how stubborn lung, wound and
Reposted by Water Me Loan 64 🍉🐻❄️🐾
models, studies of how the nanogels behave in living tissues and work on scaling up production. Those stages will decide whether this approach can move from a lab bench to hospital wards. For now, the concept offers a hopeful sign that chemistry and smart design can outmaneuver even hardened
November 26, 2025 at 5:15 PM
models, studies of how the nanogels behave in living tissues and work on scaling up production. Those stages will decide whether this approach can move from a lab bench to hospital wards. For now, the concept offers a hopeful sign that chemistry and smart design can outmaneuver even hardened
Reposted by Water Me Loan 64 🍉🐻❄️🐾
partnership between Swansea University and Freie Universität Berlin, blending expertise in chemistry, polymer science and nanotechnology. Funding from the German Science Foundation is allowing researchers to push the technology further at Swansea. The next steps will likely include tests in animal
November 26, 2025 at 5:15 PM
partnership between Swansea University and Freie Universität Berlin, blending expertise in chemistry, polymer science and nanotechnology. Funding from the German Science Foundation is allowing researchers to push the technology further at Swansea. The next steps will likely include tests in animal
Reposted by Water Me Loan 64 🍉🐻❄️🐾
human cells, at least in these early studies. Because the core gel, sugars and peptide can all be swapped or tuned, the platform IS flexible. In the future, scientists could tailor different sugar patterns AND antimicrobial fragments to match other dangerous microbes. This work reflects a
November 26, 2025 at 5:14 PM
human cells, at least in these early studies. Because the core gel, sugars and peptide can all be swapped or tuned, the platform IS flexible. In the future, scientists could tailor different sugar patterns AND antimicrobial fragments to match other dangerous microbes. This work reflects a
Reposted by Water Me Loan 64 🍉🐻❄️🐾
micrograms per milliliter. Safety tests gave encouraging results. Fibroblasts, which represent human connective tissue cells, kept OVER 80% viability at nanogel levels up to 1 milligram per milliliter. Red blood cells showed no significant damage. For us, this means the material looks gentle on
November 26, 2025 at 5:13 PM
micrograms per milliliter. Safety tests gave encouraging results. Fibroblasts, which represent human connective tissue cells, kept OVER 80% viability at nanogel levels up to 1 milligram per milliliter. Red blood cells showed no significant damage. For us, this means the material looks gentle on
Reposted by Water Me Loan 64 🍉🐻❄️🐾
against Escherichia coli and methicillin resistant Staphylococcus aureus, better known as MRSA. Those bacteria did not bind the sugars as strongly, so higher doses were needed. Even so, the system still achieved around 90% inhibition of E. coli at 32 micrograms per milliliter and MRSA at 16
November 26, 2025 at 5:13 PM
against Escherichia coli and methicillin resistant Staphylococcus aureus, better known as MRSA. Those bacteria did not bind the sugars as strongly, so higher doses were needed. Even so, the system still achieved around 90% inhibition of E. coli at 32 micrograms per milliliter and MRSA at 16
Reposted by Water Me Loan 64 🍉🐻❄️🐾
Researchers also watched the effect over time. The killing did not fade after a quick hit. The nanogel kept suppressing bacterial growth for more than three days, which suggests it could help stop infections from bouncing back. Researchers did not stop at one pathogen either. They tested the nanogel
November 26, 2025 at 5:12 PM
Researchers also watched the effect over time. The killing did not fade after a quick hit. The nanogel kept suppressing bacterial growth for more than three days, which suggests it could help stop infections from bouncing back. Researchers did not stop at one pathogen either. They tested the nanogel
Reposted by Water Me Loan 64 🍉🐻❄️🐾
wiped out MORE THAN 99.9% of the bacteria hiding inside those biofilms. Microscopy backed up the numbers. Scanning electron images showed bacteria that looked crumpled and collapsed after exposure. Confocal imaging revealed biofilms that had thinned, broken and lost their smooth structure.
November 26, 2025 at 5:11 PM
wiped out MORE THAN 99.9% of the bacteria hiding inside those biofilms. Microscopy backed up the numbers. Scanning electron images showed bacteria that looked crumpled and collapsed after exposure. Confocal imaging revealed biofilms that had thinned, broken and lost their smooth structure.
Reposted by Water Me Loan 64 🍉🐻❄️🐾
inactivated MORE THAN 99.99% of free floating Pseudomonas aeruginosa WITHIN 12 hours. This alone would be impressive but the bigger test came with biofilms (these are the dense bacterial communities that cling to medical devices, lung tissue and wound beds). WITHIN 12 hours of treatment, the nanogel
November 26, 2025 at 5:10 PM
inactivated MORE THAN 99.99% of free floating Pseudomonas aeruginosa WITHIN 12 hours. This alone would be impressive but the bigger test came with biofilms (these are the dense bacterial communities that cling to medical devices, lung tissue and wound beds). WITHIN 12 hours of treatment, the nanogel
Reposted by Water Me Loan 64 🍉🐻❄️🐾
WAS designed to leave surrounding healthy cells ALONE. In early tests, human tissue cells remained largely unharmed, EVEN AT doses far higher than those needed to kill bacteria. In laboratory experiments, the results were striking. At a concentration of just 8 micrograms per milliliter, the nanogel
November 26, 2025 at 5:09 PM
WAS designed to leave surrounding healthy cells ALONE. In early tests, human tissue cells remained largely unharmed, EVEN AT doses far higher than those needed to kill bacteria. In laboratory experiments, the results were striking. At a concentration of just 8 micrograms per milliliter, the nanogel
Reposted by Water Me Loan 64 🍉🐻❄️🐾
galactose and fucose will LATCH onto those lectins. That multigrip binding pulls the particle tightly onto the bacterial surface. Once there, the attached peptide drives the next step. It punches into the microbial membrane, tears it apart and triggers rapid bacterial death. Crucially, the nanogel
November 26, 2025 at 5:08 PM
galactose and fucose will LATCH onto those lectins. That multigrip binding pulls the particle tightly onto the bacterial surface. Once there, the attached peptide drives the next step. It punches into the microbial membrane, tears it apart and triggers rapid bacterial death. Crucially, the nanogel
Reposted by Water Me Loan 64 🍉🐻❄️🐾
researchers attached two types of sugar molecules, galactose and fucose, along with a short antimicrobial peptide. The sugars are NOT random decorations. Pseudomonas aeruginosa carries proteins on its surface, called lectins, that naturally grab THESE sugars. When the nanogel enters an infected area
November 26, 2025 at 5:07 PM
researchers attached two types of sugar molecules, galactose and fucose, along with a short antimicrobial peptide. The sugars are NOT random decorations. Pseudomonas aeruginosa carries proteins on its surface, called lectins, that naturally grab THESE sugars. When the nanogel enters an infected area
Reposted by Water Me Loan 64 🍉🐻❄️🐾
harming human cells. To meet that challenge, researchers designed a flexible particle called a heteromultivalent nanogel. It sounds technical, but the idea is fairly straightforward. The nanogel acts like a guided smart bomb. The core is a soft network of linked polymers. Onto that framework,
November 26, 2025 at 5:07 PM
harming human cells. To meet that challenge, researchers designed a flexible particle called a heteromultivalent nanogel. It sounds technical, but the idea is fairly straightforward. The nanogel acts like a guided smart bomb. The core is a soft network of linked polymers. Onto that framework,
Reposted by Water Me Loan 64 🍉🐻❄️🐾
care units or with long term medical devices, that resistance can mean longer hospital stays, more complications and higher risk of death. We live in a world where that resistance is rising, and doctors urgently need treatments that can hit bacteria in free form and inside biofilms WITHOUT
November 26, 2025 at 5:06 PM
care units or with long term medical devices, that resistance can mean longer hospital stays, more complications and higher risk of death. We live in a world where that resistance is rising, and doctors urgently need treatments that can hit bacteria in free form and inside biofilms WITHOUT
Reposted by Water Me Loan 64 🍉🐻❄️🐾
open wounds. Once it settles on a surface, it creates a biofilm, a sticky three dimensional layer that shields the bacteria from antibiotics and the immune system. In that fortified state, the microbes can survive high doses of drugs that would normally clear an infection. For patients in intensive
November 26, 2025 at 5:05 PM
open wounds. Once it settles on a surface, it creates a biofilm, a sticky three dimensional layer that shields the bacteria from antibiotics and the immune system. In that fortified state, the microbes can survive high doses of drugs that would normally clear an infection. For patients in intensive
Reposted by Water Me Loan 64 🍉🐻❄️🐾
Swansea University has unveiled a tiny new weapon that almost completely wipes this superbug out.
Why is Pseudomonas aeruginosa so hard to kill? Pseudomonas aeruginosa preys on people when they are most vulnerable. It often infects those with weak immune systems, chronic lung disease or
Why is Pseudomonas aeruginosa so hard to kill? Pseudomonas aeruginosa preys on people when they are most vulnerable. It often infects those with weak immune systems, chronic lung disease or
November 26, 2025 at 5:04 PM
Swansea University has unveiled a tiny new weapon that almost completely wipes this superbug out.
Why is Pseudomonas aeruginosa so hard to kill? Pseudomonas aeruginosa preys on people when they are most vulnerable. It often infects those with weak immune systems, chronic lung disease or
Why is Pseudomonas aeruginosa so hard to kill? Pseudomonas aeruginosa preys on people when they are most vulnerable. It often infects those with weak immune systems, chronic lung disease or
Reposted by Water Me Loan 64 🍉🐻❄️🐾
The study has been published in Angewandte Chemie. YES, it is PEER-REVIEWED.
• onlinelibrary.wiley.com/doi/10.1002/...
🧪🧵⬇️
• onlinelibrary.wiley.com/doi/10.1002/...
🧪🧵⬇️
November 26, 2025 at 5:03 PM
The study has been published in Angewandte Chemie. YES, it is PEER-REVIEWED.
• onlinelibrary.wiley.com/doi/10.1002/...
🧪🧵⬇️
• onlinelibrary.wiley.com/doi/10.1002/...
🧪🧵⬇️
Reposted by Water Me Loan 64 🍉🐻❄️🐾
The innovation centres on a heteromultivalent nanogel: a flexible particle made by crosslinking polymers and adding sugar residues alongside antimicrobial peptides.
• www.swansea.ac.uk/press-office...
• www.swansea.ac.uk/press-office...
November 26, 2025 at 5:01 PM
The innovation centres on a heteromultivalent nanogel: a flexible particle made by crosslinking polymers and adding sugar residues alongside antimicrobial peptides.
• www.swansea.ac.uk/press-office...
• www.swansea.ac.uk/press-office...
Reposted by Water Me Loan 64 🍉🐻❄️🐾
GOOD NEWS! Researchers have developed a heteromultivalent nanogel capable of killing some of the most dangerous bacteria known to medicine- with over 99.9% effectiveness against P. aeruginosa. It also showed strong antibacterial effects against other major threats, including E. coli and MRSA.
November 26, 2025 at 5:00 PM
GOOD NEWS! Researchers have developed a heteromultivalent nanogel capable of killing some of the most dangerous bacteria known to medicine- with over 99.9% effectiveness against P. aeruginosa. It also showed strong antibacterial effects against other major threats, including E. coli and MRSA.