Wafik S. El-Deiry, MD, PhD, FACP
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weldeiry.bsky.social
Wafik S. El-Deiry, MD, PhD, FACP
@weldeiry.bsky.social
Physician-Scientist Oncologist, Director Legorreta Cancer Center, Associate Dean, past Faculty Exec Cmte member, Brown Univ, ACS Professor, Chair, WIN Consortium in Precision Oncology, Entrepreneur, Boat Captain, joined Nov 16 ‘24 Pubs: tinyurl.com/s98xg3u
Pinned
On 10-26-2024 I was at Brown University Family Weekend on College Green to share exciting progress at #LegorretaCancerCenter.

As a colon cancer doctor my message was to make sure you get your screening colonoscopy to prevent colon cancer as this could save your life.

www.tiktok.com/t/ZTYLaQo9J/
I’m here at @BrownUniversity Family Weekend on the College Green to speak with you about exciting developments at the #LegorretaCancerCenter over the last few years. As a colon cancer doctor my messa...
TikTok video by weldeiry
www.tiktok.com
Dana-Farber Cancer Institute awarded $20 million for breast cancer research from Facebook cofounder’s foundation

It’s the largest non-federal grant for metastatic breast cancer research at Dana-Farber, officials said.

www.bostonglobe.com/2025/11/25/m...
Dana-Farber Cancer Institute awarded $20 million for breast cancer research from Facebook cofounder’s foundation - The Boston Globe
It’s the largest non-federal grant for metastatic breast cancer research at Dana-Farber, officials said.
www.bostonglobe.com
November 26, 2025 at 1:44 AM
Penn Medicine liable for $12.25 million in cancer misdiagnosis suit, Philadelphia jury says

www.thedp.com/article/2025...
Penn Medicine liable for $12.25 million in cancer misdiagnosis suit, Philadelphia jury says
Penn, and the plaintiff's primary physician, Janos Tanyi, were found liable for 35%, or $12.25 million, of the total verdict.
www.thedp.com
November 26, 2025 at 1:42 AM
Nearly One in 10 U.S. Adults Report Having Had Cancer

More Americans are living with a cancer diagnosis, reflecting medical progress but also a growing demand for ongoing care

news.gallup.com/poll/698108/...
Nearly One in 10 U.S. Adults Report Having Had Cancer
Nearly one in 10 Americans have been diagnosed with cancer at some point in their lifetime, even as new incidences of cancer are slowly falling.
news.gallup.com
November 26, 2025 at 1:40 AM
Optimal Duration of Androgen Deprivation Therapy With Definitive Radiotherapy for Localized Prostate Cancer

A Meta-Analysis

jamanetwork.com/journals/jam...
Optimal Duration of Androgen Deprivation Therapy With Definitive Radiotherapy for Localized Prostate Cancer
This meta-analysis examines the ideal duration of androgen deprivation therapy for patients with prostate cancer treated with radiotherapy.
jamanetwork.com
November 26, 2025 at 1:37 AM
Nivolumab plus ipilimumab induce hyper-progression in renal medullary carcinoma: results of a phase II trial and preclinical evidence

www.nature.com/articles/s41...
Nivolumab plus ipilimumab induce hyper-progression in renal medullary carcinoma: results of a phase II trial and preclinical evidence - Nature Communications
Therapeutic options for patients with renal medullary carcinoma (RMC) are limited. Here the authors report the results of a phase II clinical trial of anti-PD1 nivolumab plus anti-CTLA4 ipilimumab in ...
www.nature.com
November 26, 2025 at 1:32 AM
Seismic👇

NIH shake-up to grant decision-making draws concerns of political meddling

Policy drops “paylines” based on peer-review scores and requires geography and other factors to guide approvals

www.science.org/content/arti...
NIH shake-up to grant decision-making draws concerns of political meddling
Policy drops “paylines” based on peer-review scores and requires geography and other factors to guide approvals
www.science.org
November 26, 2025 at 1:12 AM
HHS Announces Five New Agency Leaders to Advance MAHA Goals

www.hhs.gov/press-room/h...
www.hhs.gov
November 25, 2025 at 1:16 AM
FDA approves pembrolizumab with enfortumab vedotin-ejfv for muscle invasive bladder cancer

www.fda.gov/drugs/resour...
FDA approves pembrolizumab with enfortumab vedotin-ejfv
On November 21, 2025, the Food and Drug Administration approved pembrolizumab (Keytruda, Merck) or pembrolizumab and berahyaluronidase alfa-pmph (Keytruda Qlex,
www.fda.gov
November 24, 2025 at 11:30 PM
Reposted by Wafik S. El-Deiry, MD, PhD, FACP
Such a shame about Tatiana Schlossberg's AML. I wish there was something I could do. I gave a talk at Brown about this disease about 2.5 years ago; much progress has been made with targeted therapy, but apparently not enough. @weldeiry.bsky.social
November 23, 2025 at 3:00 PM
Happy 28th anniversary dear Evelyn.
November 23, 2025 at 9:22 AM
A good practice is to look at primary references after any google search, LLM or AI summary👇

Experimental evidence of the effects of large language models versus web search on depth of learning

academic.oup.com/pnasnexus/ar...
Experimental evidence of the effects of large language models versus web search on depth of learning
Abstract. The effects of using large language models (LLMs) versus traditional web search on depth of learning are explored. A theory is proposed that when
academic.oup.com
November 23, 2025 at 1:54 AM
ACIP attacked for urging 'shared decision-making'

CDC advisers voted for patient choice on Covid shots. But the establishment claims it's an "abdication of responsibility."

open.substack.com/pub/maryanne...
ACIP attacked for urging ‘shared decision-making’
CDC advisers voted for patient choice on Covid shots. But the establishment claims it’s an “abdication of responsibility.”
open.substack.com
November 22, 2025 at 11:46 PM
So sad. We need more research to find cures for leukemia and other cancers.

Tatiana Schlossberg, Caroline Kennedy’s daughter, reveals terminal cancer diagnosis

www.bostonglobe.com/2025/11/22/m...
Tatiana Schlossberg, Caroline Kennedy’s daughter, reveals terminal cancer diagnosis - The Boston Globe
Schlossberg, 35, was diagnosed with acute myeloid leukemia, with a rare mutation found in less than 2 percent of cases.
www.bostonglobe.com
November 22, 2025 at 9:59 PM
Biggest prostate cancer screening trial in decades begins in UK

www.bbc.com/news/article...
Prostate cancer screening trial to recruit thousands of men
The study aims to find the best way to detect prostate cancer - the most common cancer in men in the UK.
www.bbc.com
November 22, 2025 at 1:53 PM
Great meeting with some #eldeirylab members who recently joined including @BrownMedicine medical student Chris Egg-Krings, & Brown undergraduates Samarth Bedre and Harrison Yu. We discussed their research focused on brain cancers, careers in academic medicine, collaboration & strategies for impact.
November 22, 2025 at 12:40 AM
We enjoyed having Jeff Waldron, a Brown Alum and his class reunion organizer visit with us at #LegorretaCancerCenter to learn about progress and future directions at the cancer center. Exciting things are happening at @BrownUniversity, @BrownMedicine, and @BrownUnivHealth.
November 22, 2025 at 12:21 AM
GSK3B directs DNA repair choice and determines tumor response to PARP1 inhibition independent of BRCA1

www.jci.org/articles/vie...
JCI - GSK3B directs DNA repair choice and determines tumor response to PARP1 inhibition independent of BRCA1
www.jci.org
November 21, 2025 at 3:18 AM
RAS(ON) multi-selective inhibition drives antitumor immunity in preclinical models of NRAS-mutant melanoma

aacrjournals.org/cancerimmuno...
RAS(ON) multi-selective inhibition drives antitumor immunity in preclinical models of NRAS-mutant melanoma
Abstract. Targeted therapies for NRAS-mutant melanoma remain an unmet clinical need. Here, we demonstrate that RMC-7977, a preclinical RAS(ON) multi-selective inhibitor representative of the investiga...
aacrjournals.org
November 21, 2025 at 2:55 AM