Zhang et al. eccDNABase, a comprehensive and curated resource for browsing, searching, and analyzing Extrachromosomal circular DNAs across multiple species.

🔗 doi.org/10.1093/molbev/msaf223

#evobio #molbio #compbio

5/5: Given its extensive and curated datasets, eccDNABase serves as a valuable resource for both basic and translational research, offering deeper insights into the role of eccDNA in health and disease. The database is publicly accessible at cgga.org.cn/eccDNABase/.

4/5: Each entry provides detailed information, including eccDNA ID, type, chromosomal localization, species, tissue or cell line source, disease name and Disease Ontology ID, overlap length and percentage with genes, oncogene overlap, detection method, and links to literature and source databases.

3/5: Currently, eccDNABase contains 1,875,452 eccDNA–disease associations, encompassing 8,398 ecDNA entries across nine species, 63 diseases, and healthy individuals.

2/5: The eccDNABase is a comprehensive and curated resource for browsing, searching, and analyzing eccDNAs across multiple species. The database systematically catalogs eccDNA-disease associations from diverse tissues and organisms.

1/5: ☺️☺️ Recently, we have published a database paper in the MBE journal @molbioevol.bsky.social titled "eccDNABase: A Comprehensive and High-Quality Database for Extrachromosomal Circular DNA". #eccDNA #disease #multi_species

academic.oup.com/mbe/article/...