a-nia.bsky.social
@a-nia.bsky.social
Excited to share our work! How do lysosomes change with age? We present a metabolic atlas of lysosomal aging, and reveal a lysosomal “aging clock” of metabolites linked to lysosomal storage disorders. Grateful to all co-authors!
www.biorxiv.org/cgi/content/...
Atlas of Lysosomal Aging Reveals a Molecular Clock of Storage Disorder-Associated Metabolites
Lysosomal dysfunction is a well-recognized feature of aging, yet its systematic molecular investigation remains limited. Here, we employ a suite of tools for rapid lysosomal isolation to construct a m...
www.biorxiv.org
September 27, 2025 at 2:20 AM