A Bakalakos
@abakalakos.bsky.social
Cardiologist | Clinical Research Fellow @ucl.ics, @uclpophealthsci.bsky.social
Heart Muscle Disease, Cardiogenetics
Heart Muscle Disease, Cardiogenetics
Childhood-onset RASopathy-associated hypertrophic cardiomyopathy, diastolic dysfunction, and arrhythmias url: academic.oup.com/eurheartj/ar...
Childhood-onset RASopathy-associated hypertrophic cardiomyopathy, diastolic dysfunction, and arrhythmias
The RASopathies account for ∼18%1 of childhood hypertrophic cardiomyopathy (HCM) cases and up to 42%2 of infantile (<1 year of age) presentations, makin
academic.oup.com
December 24, 2025 at 4:29 PM
Childhood-onset RASopathy-associated hypertrophic cardiomyopathy, diastolic dysfunction, and arrhythmias url: academic.oup.com/eurheartj/ar...
Reposted by A Bakalakos
NEW Focus issue on Metabolic alterations in heart failure:
-Cardiac intermediary metabolism
-Vascular (dys)function
-Immunometabolism
-Mechano-energetic uncoupling
Plus
-Mitochondrial quality control in cardiomyocytes
-Tailored therapeutics for cardiomyopathies
www.nature.com/nrcardio/vol...
-Cardiac intermediary metabolism
-Vascular (dys)function
-Immunometabolism
-Mechano-energetic uncoupling
Plus
-Mitochondrial quality control in cardiomyocytes
-Tailored therapeutics for cardiomyopathies
www.nature.com/nrcardio/vol...
September 15, 2025 at 8:24 PM
NEW Focus issue on Metabolic alterations in heart failure:
-Cardiac intermediary metabolism
-Vascular (dys)function
-Immunometabolism
-Mechano-energetic uncoupling
Plus
-Mitochondrial quality control in cardiomyocytes
-Tailored therapeutics for cardiomyopathies
www.nature.com/nrcardio/vol...
-Cardiac intermediary metabolism
-Vascular (dys)function
-Immunometabolism
-Mechano-energetic uncoupling
Plus
-Mitochondrial quality control in cardiomyocytes
-Tailored therapeutics for cardiomyopathies
www.nature.com/nrcardio/vol...
Reposted by A Bakalakos
New online! Tailored therapeutics for cardiomyopathies #CardioSky
Tailored therapeutics for cardiomyopathies
Nature Reviews Cardiology, Published online: 27 June 2025; doi:10.1038/s41569-025-01183-6Treatment of cardiomyopathies has historically focused on symptom management. In this Review, Elliott and colleagues discuss how elucidation of the complex cellular and molecular pathways has led to the development of novel therapeutic agents that modify or mitigate the effects of causative genetic variants, enabling tailored treatment for cardiomyopathies.
bit.ly
June 27, 2025 at 11:58 AM
New online! Tailored therapeutics for cardiomyopathies #CardioSky
Reposted by A Bakalakos
Nature journalists will be at #StandUpForScience protests across the US later today; and in France the actions have already begun. Events will take place in more than 30 French cities, says @standupforscifr.bsky.social
Scientists in France are choosing to #StandUpForScience alongside their US colleagues. Signatories to a supporting column in @lemonde.fr include two Nobel laureates, economist Esther Duflo and virologist Françoise Barré-Sinoussi. www.lemonde.fr/sciences/art...
March 7, 2025 at 12:34 PM
Nature journalists will be at #StandUpForScience protests across the US later today; and in France the actions have already begun. Events will take place in more than 30 French cities, says @standupforscifr.bsky.social
Reposted by A Bakalakos
Stay tuned for our live coverage of #StandUpForScience, here on Bluesky 🧪
March 7, 2025 at 12:38 PM
Stay tuned for our live coverage of #StandUpForScience, here on Bluesky 🧪
Reposted by A Bakalakos
To everyone in the U.S. standing up for science today, calling for policies that support science, not suppress it: we’re with you! Cutting science doesn’t just harm scientists – it harms society as a whole. #StandUpForScience
March 7, 2025 at 11:50 AM
To everyone in the U.S. standing up for science today, calling for policies that support science, not suppress it: we’re with you! Cutting science doesn’t just harm scientists – it harms society as a whole. #StandUpForScience
Bluesky adds 700,000 new members as users flee X after the US election www.theguardian.com/technology/2...
November 13, 2024 at 10:21 PM
Bluesky adds 700,000 new members as users flee X after the US election www.theguardian.com/technology/2...