The framework works across species & drug classes — and the code is open-source. Would love to hear feedback from those working in AMR surveillance!
Preprint: www.biorxiv.org/content/10.1...

Applied to 3,600+ pneumococcal isolates, AMR Cartography revealed lineage-specific resistance and the genetic changes driving multidrug resistance.

Instead of treating correlations between drugs as noise, we use them as insight.
That lets us see:
• subtle shifts before breakpoints
• co-resistance patterns
• collateral sensitivity trade-offs
• identify genetic markers for resistance

In our new preprint we introduce AMR Cartography: a way to map full resistance profiles into simple 2D maps.

By ignoring that structure, we lose the early warning signs of resistance emerging — and miss how resistance evolves in real populations.