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abbybartlett.bsky.social
Abby Bartlett
@abbybartlett.bsky.social
54 followers 90 following 2 posts
Mitochondrial biology, rare disease awareness and advocacy, writing, and life in (and after!) grad school 💚
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Reposted by Abby Bartlett
edreesrashan.bsky.social
Eddie Rashan @edreesrashan.bsky.social · Jun 22
AND IT'S DONE! A 🧵 on our recent article now out in @natsmb.nature.com! Co-led with @abbybartlett.bsky.social, Pagliarini Lab, @judisimcox.bsky.social, we find ACAD10/11 are NOT like other acyl-CoA dehydrogenases and instead catabolize atypical lipids called 4-hydroxy acids 🤯 doi.org/10.1038/s415...
ACAD10 and ACAD11 enable mammalian 4-hydroxy acid lipid catabolism - Nature Structural & Molecular Biology
Rashan, Bartlett and colleagues show that mammalian 4-hydroxy fatty acids are primarily catabolized by ACAD10 and ACAD11 (atypical mitochondrial and peroxisomal acyl-CoA dehydrogenases, respectively) ...
doi.org
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abbybartlett.bsky.social
Abby Bartlett @abbybartlett.bsky.social · Jun 19
Very excited to see this work with @edreesrashan.bsky.social published in @natsmb.nature.com ! #metabolism #AmazingACADs 🤩
natsmb.nature.com
Nature Structural & Molecular Biology @natsmb.nature.com · Jun 19
New online: ACAD10 and ACAD11 enable mammalian 4-hydroxy acid lipid catabolism
ACAD10 and ACAD11 enable mammalian 4-hydroxy acid lipid catabolism
Nature Structural & Molecular Biology, Published online: 19 June 2025; doi:10.1038/s41594-025-01596-4Rashan, Bartlett and colleagues show that mammalian 4-hydroxy fatty acids are primarily catabolized by ACAD10 and ACAD11 (atypical mitochondrial and peroxisomal acyl-CoA dehydrogenases, respectively) that use phosphorylation in their reaction mechanisms.
go.nature.com
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abbybartlett.bsky.social
Abby Bartlett @abbybartlett.bsky.social · Jan 22
Congrats! 👏
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