Alejandro Blenkmann
@ablenkmann.bsky.social
150 followers 260 following 25 posts
Neuroscientist | PI of AudioPred at @UniOslo-RITMO.bsky.social Studying predictive processing & developing intracranial EEG methods Personal page: https://bit.ly/aBlenkmann #cognition #iEEG #SEEG #perception #attention #neuroscience #predictiveprocessing
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ablenkmann.bsky.social
🤔How does the human brain predict unexpected sounds?
Our new study shows that the prefrontal cortex doesn’t work as a single unit. Instead, the orbitofrontal and lateral prefrontal cortex make distinct, time-sensitive contributions. #iEEG #BrainLesion #OFC #LPFC
doi.org/10.1101/2025...
Predictive encoding of auditory sequences in the human prefrontal cortex
Humans extract regularities from the environment to form expectations that guide perception and optimize behavior. Although the prefrontal cortex (PFC) is central to this process, the relative contrib...
doi.org
Reposted by Alejandro Blenkmann
randolph-helfrich.bsky.social
New position, new social media account. After 5 fantastic years in Tuebingen, I moved to @yale.edu and the @wutsaiyale.bsky.social this summer - which means that I’ll be recruiting PhD students and postdocs. Please help me to spread the word and see current opportunities below 👇
ablenkmann.bsky.social
🚨 Join me for a hands-on #iElectrodes tutorial at #PracticalMEEG!
📍 Online • 🗓 Thursday, Oct 30 • 14:00–17:00 CET
Learn how to localize intracranial electrodes — and explore many other great toolboxes:
cuttingeeg.org/practicalmee...

#iEEG #ECoG #SEEG
ablenkmann.bsky.social
👏 Huge congratulations to Olgerta Asko, who led this work, and to our fantastic collaborators at @unioslo-ritmo.bsky.social, @ucberkeleyofficial.bsky.social cial.bsky.social, and @oushf.bsky.social sky.social.
🙏 Special thanks to the patients who made this research possible.
cial.bsky.social
cial.bsky.social
ablenkmann.bsky.social
👩‍🔬👨‍🔬 Together, these results provide electrophysiological and causal evidence that the human prefrontal cortex predicts future sounds through distinct, time-ordered roles of OFC and LPFC.
Read the full preprint here 👉 doi.org/10.1101/2025...
Predictive encoding of auditory sequences in the human prefrontal cortex
Humans extract regularities from the environment to form expectations that guide perception and optimize behavior. Although the prefrontal cortex (PFC) is central to this process, the relative contrib...
doi.org
ablenkmann.bsky.social
Intracranial EEG shows expectancy modulations in the prefrontal cortex:
🧠 OFC earlier
🧠 LPFC later
(This was measured via high-frequency activity, a marker of local brain activity)

Connectivity analyses reveal bidirectional exchange, with the first lead by OFC.

#iEEG #PredictiveProcessing #HFA
ablenkmann.bsky.social
Lesion evidence indicates distinct roles:
🧠 Orbitofrontal cortex (OFC) damage abolishes sensitivity to expectancy.
🧠 Lateral prefrontal cortex (LPFC) damage shows only modest, non-significant effects compared to controls.
(Shown using #CNV #ERP that tracks anticipation)

#BrainLesion #Prediction
ablenkmann.bsky.social
In an auditory local–global deviance detection task, we found that the brain tracks sound regularities to anticipate when a rare deviant sequence will occur.
⚡ Participants detected deviants faster when they were expected.

#PredictiveProcessing
ablenkmann.bsky.social
🤔How does the human brain predict unexpected sounds?
Our new study shows that the prefrontal cortex doesn’t work as a single unit. Instead, the orbitofrontal and lateral prefrontal cortex make distinct, time-sensitive contributions. #iEEG #BrainLesion #OFC #LPFC
doi.org/10.1101/2025...
Predictive encoding of auditory sequences in the human prefrontal cortex
Humans extract regularities from the environment to form expectations that guide perception and optimize behavior. Although the prefrontal cortex (PFC) is central to this process, the relative contrib...
doi.org
Reposted by Alejandro Blenkmann
auksz.bsky.social
Job alert 🚨 Fully funded PhD position available in our Maastricht lab! Are you interested in predictive processing, individual differences, and computational modelling of behavioural and neural data? Please apply! #NeuroJobs vacancies.maastrichtuniversity.nl/job/Maastric...
PhD Candidate: cognitive computational neuroscience of individual differences
PhD Candidate: cognitive computational neuroscience of individual differences
vacancies.maastrichtuniversity.nl
Reposted by Alejandro Blenkmann
Reposted by Alejandro Blenkmann
Reposted by Alejandro Blenkmann
lcparra.bsky.social
Evidence in support of the "Brain from the inside out":

Response to movies is dominated by intrinsic brain dynamics. The dynamic itself is barely alternatered by the task of watching movies.

Human intracranial recordings from 5000 electrodes, now out in eLife.

elifesciences.org/reviewed-pre...
Reposted by Alejandro Blenkmann
fedemar.bsky.social
PhD position alert!!!
Together with @predictivebrain.bsky.social and Sonja Kotz we are looking for a PhD candidate to join a great project on the biological foundations of perceptual decisions vacancies.maastrichtuniversity.nl/job/Maastric...

Happy to answer any question you may have!
PhD position in biological foundations of neural control
PhD position in biological foundations of neural control
vacancies.maastrichtuniversity.nl
Reposted by Alejandro Blenkmann
predictivebrain.bsky.social
🚨PhD position alert!🚨
Joint PhD position with @fedemar.bsky.social @predictivebrain.bsky.social and Sonja Kotz, to investigate the neurobiological underpinnings of perceptual decisions
vacancies.maastrichtuniversity.nl/job/Maastric...
Please share and if you have questions, send me a message!
PhD position in biological foundations of neural control
PhD position in biological foundations of neural control
vacancies.maastrichtuniversity.nl
ablenkmann.bsky.social
Don't miss the chance to apply to work with Andres.
He is a great researcher in the field of predictive processing, working with #iEEG across humans and non-human primates
canalesjohnson.bsky.social
I am opening one PhD position at the Neuroscience Center @uhneuro.bsky.social, focusing on large-scale neural interactions in perception and prediction (ECoG/LFPs/MEG) across human and non-human primates using comp. modeling and information theory. contact: www.helsinki.fi/en/hilife-he...
Large-scale interactions in perception and prediction across species | HiLIFE – Helsinki Institute of Life Science | University of Helsinki
Andres Canales-Johnson research group
www.helsinki.fi
Reposted by Alejandro Blenkmann
agreco.bsky.social
🚨 New preprint! 🚨
Can humans learn sensory regularities that are irrelevant to ongoing behavior? Yes, and we reveal the predictive coding mechanisms behind their acquisition

Our results support uncertainty minimization over environmental state transitions as a core objective of brain function

🧵👇
ablenkmann.bsky.social
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Thanks to our fantastic team and collaborators across Oslo, Cambridge, Berkeley, and Buenos Aires!

📄 Read the full paper: doi.org/10.1038/s415...
https://doi.org/10.1038/s41598-025-98865-5🧠
ablenkmann.bsky.social
7/
🔬 This work has implications for cognitive neuroscience, especially in understanding how structure is extracted from seemingly unstructured input, and bridges predictive coding and statistical learning.
ablenkmann.bsky.social
6/
💥 Our findings reshape how we understand statistical learning: the brain doesn't just react—it constantly builds models of the world.
This study shows, for the first time, that the brain implicitly encodes transitional probabilities in random streams without attention or intention.
ablenkmann.bsky.social
5/
🧠 Key finding: TP encoding wasn’t limited to auditory cortex.
Hippocampus and inferior frontal gyrus showed strongest sensitivity to TPs.
Auditory cortex responded more to deviance per se, but statistical learning was distributed– and hierarchical.
ablenkmann.bsky.social
4/
Using an information-theoretical approach, we quantified how much information each brain response "encoded" relative to expected patterns.
Then, we tested how this encoded information tracked the likelihood of transitions– aka transitional probabilities (TPs).