Simulated microgravity induces distinct mitochondrial hyperactivation patterns-elevated OXPHOS and MMP-which accelerate meiosis without SAC failure but delays MTOC coalescence, leading to spindle def...

We developed a rapid, high-throughput XL–MS workflow using the enrichable azide-A-DSBSO cross-linker and StageTip-based SCX fractionation. It drastically reduces preparation time and enhances sensiti...

Li et al. further develop a high-throughput peptide-centric local stability assay that speeds up sample preparation 100-fold and extends protein–ligand identification to membrane proteins, tissues and...

Absea develops, engineers and characterizes protein and antibody reagents with unprecedented throughput and quality. We strive to provide products, services and tools to break new ground in protein re...

Absea develops, engineers and characterizes protein and antibody reagents with unprecedented throughput and quality. We strive to provide products, services and tools to break new ground in protein re...

The field of blood proteomics faces an upsurge of data with the challenge of cross-study comparisons. This Perspective offers an in-depth analysis and proposes reference materials to enhance data integration and accelerate clinical translation.