Anne C. Hart
@ach-ceneuro.bsky.social
760 followers 760 following 95 posts
Neuroscientist, geneticist, educator, mentor, loves C. elegans, puns, birds, sci-fi/fantasy and kinda nerdy. You get my personal opinions here! 🌈
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Reposted by Anne C. Hart
antebilab.bsky.social
🚨New @biorxivpreprint: We model the splicing factor disease Verheij syndrome using C. elegans. Disruption of methionine and phospholipid metabolism drives growth defects; vitamin #B12 restores metabolic balance and rescues development! #metabolism #Celegans #RNAsplicing
doi.org/10.1101/2025...
Vitamin B12 alleviates Verheij syndrome-like defects via phospholipid remodeling in a C. elegans PUF60 spliceosomopathy model
Verheij syndrome (VRJS) is a rare genetic disorder caused by mutations in the poly(U)-binding splicing factor 60 (PUF60), a core component of the spliceosomal complex. VRJS triggers multiple congenita...
doi.org
ach-ceneuro.bsky.social
Why not require more “flipped” classes — pre-recorded lectures & mandatory in-class work, such as small group problem solving, peer-to-peer presentations, daily quizzes, discussing primary literature?

Clearly, I’m not a fan of letting students enroll in two classes that meet at the same time
ach-ceneuro.bsky.social
Hesgeth forced our senior military officials to travel back to Quantico for his nonsense “speech”.

Our generals know that this was a total waste of their time — but they are too professional, disciplined and tactical to announce their opinions in public…for now.
ach-ceneuro.bsky.social
All of these are good ideas. I can personally confirm how useful 4% of these tips are…🤣
ach-ceneuro.bsky.social
Sibling studies for me!
Study of siblings shows taking acetaminophen does not increase autism/ADHD risk…this is a rigorous science
ach-ceneuro.bsky.social
Sadly, I suspect this would involve even more painful committee service
ach-ceneuro.bsky.social
Oh no! Ed was wonderful - so sad to hear about this
Reposted by Anne C. Hart
astrokatie.com
Look you can’t tell me this thing is “intelligently designed” — it goes into a five-minute coughing fit if I breathe wrong. Sometimes it accidentally bites itself. It draws blood.
ach-ceneuro.bsky.social
Mei is an amazing scientist! This a a well-deserved honor!
ach-ceneuro.bsky.social
New #postdoc position focused on ALS/FTD available in the Hart lab! Join the collaborative Brown Univ. #neuroscience community! Experience with invertebrate genetics (like #Celegans) and/or neurodegenerative disease is welcome, but not required. Details at apply.interfolio.com/172914
ach-ceneuro.bsky.social
Thanks for these examples — which I can use in my explanations of large language models and “AI”
Reposted by Anne C. Hart
propublica.org
People experiencing miscarriages in states with abortion bans told us they wished they had known what to expect and how to advocate for themselves.

We created this guide for anyone who finds themselves in the same position.

(Published Dec. 2024)
If You’re Pregnant, Here’s What You Should Know About the Medical Procedures That Could Save Your Life
Women experiencing pregnancy loss in states with abortion bans told us they wished they had known what to expect and how to advocate for themselves. We created this guide for anyone who finds themselv...
www.propublica.org
ach-ceneuro.bsky.social
Local experience and observation may help you predict how much the area usually lags behind predictions, but if very shallow, then strong/steady winds from specific directions may also change max low tide. Tips at www.reddit.com/r/boating/co...
From the boating community on Reddit
Explore this post and more from the boating community
www.reddit.com
ach-ceneuro.bsky.social
The new Executive Order also gives the NIH a straight-forward strategy for denying grants to outspoken scientists, regardless of their institution, field of research or state of residence. Basically, this allows punishment of free-speech…
ach-ceneuro.bsky.social
Adorable! Hope y’all had fun!
ach-ceneuro.bsky.social
Not great yet. 😭 And, heading the wrong direction…

At least you know this objective is high quality & should last decades (based on personal experience)
ach-ceneuro.bsky.social
Ask a C. elegans lab on the other side of the country for a strain & it arrives <48 hours later. Impressive, even for the 🪱 community - big thank you to Jihong Bai’s lab ❤️
Two plates of C. elegans, atop a FedEx shipping label
ach-ceneuro.bsky.social
Brown Univ just announced an agreement with the federal government.

While not perfect, it is not awful. I like that it involves Brown paying $50million to Rhode Island, workforce development organizations, not the federal government!