Adam Dinan
adamd3.bsky.social
Adam Dinan
@adamd3.bsky.social
I am a postdoctoral researcher at the University of Cambridge in @vpd-hlri.bsky.social and Cambridge Centre for AI in Medicine.
My interests include genomics, statistics and machine learning.
Reposted by Adam Dinan
💾 Prokka 1.15.6 is released!

This is the last major release of Prokka. But don't be sad, because @oschwengers.bsky.social already has an excellent replacement called Bakta you can migrate to.
#bioinformatics #microbiology #genomics

github.com/tseemann/pro...
Release Heading into the sunset · tseemann/prokka
The future This is probably the last release of Prokka. I won't be making any code changes except bug fixes. I will update the databases occasionally. I strongly recommend you use Bakta by @oschwen...
github.com
December 15, 2025 at 9:09 PM
Reposted by Adam Dinan
We're organising a microbes & deep learning session at SMBE next year -- looking forward to seeing your abstracts!
Organisers
- @bacpop.org | @embl.org
- @aweimann.bsky.social | University of Cambridge

Invited Speaker
- @audeber.bsky.social | Institut Pasteur
December 15, 2025 at 11:26 AM
Reposted by Adam Dinan
How do GWAS and rare variant burden tests rank gene signals?

In new work @nature.com with @hakha.bsky.social, @jkpritch.bsky.social, and our wonderful coauthors we find that the key factors are what we call Specificity, Length, and Luck!

🧬🧪🧵

www.nature.com/articles/s41...
Specificity, length and luck drive gene rankings in association studies - Nature
Genetic association tests prioritize candidate genes based on different criteria.
www.nature.com
November 7, 2025 at 12:05 AM
Reposted by Adam Dinan
Glad to be up here in Newcastle for the annual Newcastle Edinburgh Cambridge Sheffield (NECS) respiratory research meeting. Always informative, friendly and fun.
October 9, 2025 at 12:34 PM
Reposted by Adam Dinan
MMseqs2-GPU sets new standards in single query search speed, allows near instant search of big databases, scales to multiple GPUs and is fast beyond VRAM. It enables ColabFold MSA generation in seconds and sub-second Foldseek search against AFDB50. 1/n
📄 www.nature.com/articles/s41...
💿 mmseqs.com
GPU-accelerated homology search with MMseqs2 - Nature Methods
Graphics processing unit-accelerated MMseqs2 offers tremendous speedups for homology retrieval from metagenomic databases, query-centered multiple sequence alignment generation for structure predictio...
www.nature.com
September 21, 2025 at 8:06 AM
Reposted by Adam Dinan
💥 Excited to introduce Bacformer 🦠 - the first foundation model for bacterial genomics. Bacformer represents genomes as sequences of ordered proteins, learning the “grammar” of how genes are arranged, interact and evolve.

Preprint 📝: biorxiv.org/content/10.1...

🧵 1/n
July 21, 2025 at 9:56 AM