Adam Rochussen
@adamrochussen.bsky.social
15 followers 8 following 4 posts
Cell biologist / immunologist working on cytotoxic T lymphocytes
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Reposted by Adam Rochussen
jcellsci.bsky.social
New JCS snapshot - Cytotoxic T lymphocytes adapt to the loss of Cdc42
@adamrochussen.bsky.social presents the key findings from their recent JCS paper with Claire Ma and Gillian Griffiths @griffithslab.bsky.social.
journals.biologists.com/jcs/article/...
Reposted by Adam Rochussen
jcellsci.bsky.social
. @adamrochussen.bsky.social, Claire Ma & Gillian Griffiths @griffithslab.bsky.social find that deletion of Cdc42 in primary T cells triggers transcriptional adaptation, leading to enhanced T cell function.
journals.biologists.com/jcs/article/...
Article: journals.biologists.com/jcs/article/...
Multi-panel figure showing that CTL function improves days after deletion of Cdc42.
adamrochussen.bsky.social
Excited to see this published today!
griffithslab.bsky.social
Sometimes, knocking out a gene isn't a good way to figure out the function of that gene ...

In our new @jcellsci.bsky.social paper, we report potent transcriptional adaptation by cytotoxic T lymphocytes (CTLs) in response to CRISPR/Cas9-mediated deletion of the important polarity protein CDC42 🧵⬇️
adamrochussen.bsky.social
Congrats to the other awardees. Very fortunate to be included in such a stellar group of young scientists. You can read about our projects here:

csar.org.uk/student-awar...

Thanks also to @cambridgeindy.bsky.social for highlighting the awards:

premium.cambridgeindependent.co.uk/business/tru...
2025 | CSAR
csar.org.uk
adamrochussen.bsky.social
Delighted to have been awarded a CSAR 2025 PhD Student Award for some of my work in the @griffithslab.bsky.social
@thecimr.bsky.social

The CSAR mission to recognise and prioritise research with real-world application is a super important one that I'll be taking forward as a postdoc & beyond
Reposted by Adam Rochussen
griffithslab.bsky.social
Welcome to the dynamic world of T cells!