SorrentinoLab
@admlab.bsky.social
www.cell.com/cell-reports...
🎉 Our lab’s first paper is out in Cell Reports! We present a novel organotypic model of ductular reaction that recapitulates epithelial remodeling within a native microenvironment using precision cut liver slices. Huge thanks to AIRC for the support!
🎉 Our lab’s first paper is out in Cell Reports! We present a novel organotypic model of ductular reaction that recapitulates epithelial remodeling within a native microenvironment using precision cut liver slices. Huge thanks to AIRC for the support!
An organotypic model of ductular reaction reveals a mevalonate-dependent vulnerability in reactive biliary cells
Chronic liver injury triggers the ductular reaction, where biliary cells expand to
repair damage but can drive disease progression when persistent. Anfuso et al. model
this process ex vivo within a na...
www.cell.com
December 17, 2025 at 9:49 PM
www.cell.com/cell-reports...
🎉 Our lab’s first paper is out in Cell Reports! We present a novel organotypic model of ductular reaction that recapitulates epithelial remodeling within a native microenvironment using precision cut liver slices. Huge thanks to AIRC for the support!
🎉 Our lab’s first paper is out in Cell Reports! We present a novel organotypic model of ductular reaction that recapitulates epithelial remodeling within a native microenvironment using precision cut liver slices. Huge thanks to AIRC for the support!
www.mdpi.com/1424-8247/18...
Can engineered hydrogels reshape the future of biliary organoids?
Our new review explores how next-generation, fully tunable hydrogels are transforming the way we model biliary diseases in vitro.
Can engineered hydrogels reshape the future of biliary organoids?
Our new review explores how next-generation, fully tunable hydrogels are transforming the way we model biliary diseases in vitro.
www.mdpi.com
November 23, 2025 at 2:36 PM
www.mdpi.com/1424-8247/18...
Can engineered hydrogels reshape the future of biliary organoids?
Our new review explores how next-generation, fully tunable hydrogels are transforming the way we model biliary diseases in vitro.
Can engineered hydrogels reshape the future of biliary organoids?
Our new review explores how next-generation, fully tunable hydrogels are transforming the way we model biliary diseases in vitro.