Australasian Epigenetic Alliance (AEpiA)
@aepia.bsky.social
Uniting epigenetics researchers across Australasia
https://www.aepia.org.au/
DMs not monitored, email [email protected]
https://www.aepia.org.au/
DMs not monitored, email [email protected]
Join the AEpiA community and be part of Australia’s growing epigenetics network.
AEpiA members receive discounted conference registration, a great reason to get involved ahead of #AEpiA2026!
Join at: www.aepia.org.au/becomeamember
AEpiA members receive discounted conference registration, a great reason to get involved ahead of #AEpiA2026!
Join at: www.aepia.org.au/becomeamember
Become a Member — Australasian Epigenetics Alliance
www.aepia.org.au
February 13, 2026 at 1:27 AM
Join the AEpiA community and be part of Australia’s growing epigenetics network.
AEpiA members receive discounted conference registration, a great reason to get involved ahead of #AEpiA2026!
Join at: www.aepia.org.au/becomeamember
AEpiA members receive discounted conference registration, a great reason to get involved ahead of #AEpiA2026!
Join at: www.aepia.org.au/becomeamember
Thank you again to everyone who participated in the event. We are so delighted that so many of you joined us and contributed to the energy in the room (and on Zoom!).
#AEpiA #Epigenetics #EMCR #ResearchCommunity #CareerDevelopment #ScientificNetworking
#AEpiA #Epigenetics #EMCR #ResearchCommunity #CareerDevelopment #ScientificNetworking
December 5, 2025 at 10:49 PM
Thank you again to everyone who participated in the event. We are so delighted that so many of you joined us and contributed to the energy in the room (and on Zoom!).
#AEpiA #Epigenetics #EMCR #ResearchCommunity #CareerDevelopment #ScientificNetworking
#AEpiA #Epigenetics #EMCR #ResearchCommunity #CareerDevelopment #ScientificNetworking
📝 Join the AEpiA Community
Not an AEpiA member yet? Membership is free for students and discounted for ECRs. Joining gives you access to AEpiA initiatives, events, awards and networking opportunities throughout the year. 👉 Become a member today www.aepia.org.au/becomeamember
Not an AEpiA member yet? Membership is free for students and discounted for ECRs. Joining gives you access to AEpiA initiatives, events, awards and networking opportunities throughout the year. 👉 Become a member today www.aepia.org.au/becomeamember
Become a Member — Australasian Epigenetics Alliance
www.aepia.org.au
December 5, 2025 at 10:49 PM
📝 Join the AEpiA Community
Not an AEpiA member yet? Membership is free for students and discounted for ECRs. Joining gives you access to AEpiA initiatives, events, awards and networking opportunities throughout the year. 👉 Become a member today www.aepia.org.au/becomeamember
Not an AEpiA member yet? Membership is free for students and discounted for ECRs. Joining gives you access to AEpiA initiatives, events, awards and networking opportunities throughout the year. 👉 Become a member today www.aepia.org.au/becomeamember
From venue logistics to catering, AV checks, and troubleshooting unexpected challenges on the day, our organising committee were a huge part of the event success
December 5, 2025 at 10:49 PM
From venue logistics to catering, AV checks, and troubleshooting unexpected challenges on the day, our organising committee were a huge part of the event success
👏 Thank you
Event conveners @scientistkate.bsky.social and Alex Woodworth would like to thank our organising team Ashleigh Geiger, Marion Turpin, Katrina Mitchell, Eleanor Glancy, @scholarticone.bsky.social, Chris Siu Yeung Chow, @trungbiotech.bsky.social, @braydonsci.bsky.social & Rachel Woodhouse
Event conveners @scientistkate.bsky.social and Alex Woodworth would like to thank our organising team Ashleigh Geiger, Marion Turpin, Katrina Mitchell, Eleanor Glancy, @scholarticone.bsky.social, Chris Siu Yeung Chow, @trungbiotech.bsky.social, @braydonsci.bsky.social & Rachel Woodhouse
December 5, 2025 at 10:49 PM
👏 Thank you
Event conveners @scientistkate.bsky.social and Alex Woodworth would like to thank our organising team Ashleigh Geiger, Marion Turpin, Katrina Mitchell, Eleanor Glancy, @scholarticone.bsky.social, Chris Siu Yeung Chow, @trungbiotech.bsky.social, @braydonsci.bsky.social & Rachel Woodhouse
Event conveners @scientistkate.bsky.social and Alex Woodworth would like to thank our organising team Ashleigh Geiger, Marion Turpin, Katrina Mitchell, Eleanor Glancy, @scholarticone.bsky.social, Chris Siu Yeung Chow, @trungbiotech.bsky.social, @braydonsci.bsky.social & Rachel Woodhouse
🙏 𝗧𝗵𝗮𝗻𝗸 𝗬𝗼𝘂 𝘁𝗼 𝗢𝘂𝗿 𝗦𝗽𝗼𝗻𝘀𝗼𝗿𝘀 𝗮𝗻𝗱 𝗣𝗮𝗿𝘁𝗻𝗲𝗿𝘀
This event would not have been possible without the support of NovogeneAIT Genomics, Integrated Sciences, New England Biolabs and AGRF Ltd. Your partnership helps us continue delivering opportunities for EMCRs across Australia.
This event would not have been possible without the support of NovogeneAIT Genomics, Integrated Sciences, New England Biolabs and AGRF Ltd. Your partnership helps us continue delivering opportunities for EMCRs across Australia.
December 5, 2025 at 10:49 PM
🙏 𝗧𝗵𝗮𝗻𝗸 𝗬𝗼𝘂 𝘁𝗼 𝗢𝘂𝗿 𝗦𝗽𝗼𝗻𝘀𝗼𝗿𝘀 𝗮𝗻𝗱 𝗣𝗮𝗿𝘁𝗻𝗲𝗿𝘀
This event would not have been possible without the support of NovogeneAIT Genomics, Integrated Sciences, New England Biolabs and AGRF Ltd. Your partnership helps us continue delivering opportunities for EMCRs across Australia.
This event would not have been possible without the support of NovogeneAIT Genomics, Integrated Sciences, New England Biolabs and AGRF Ltd. Your partnership helps us continue delivering opportunities for EMCRs across Australia.
A highlight of the day was our Career Panel. A huge thank you to @nireynon.bsky.social, @aachinger.bsky.social, Luke Isbel and Dhanya Sooraj for sharing their insights, experiences, and advice. Your openness and encouragement were deeply appreciated by our EMCR community.
December 5, 2025 at 10:49 PM
A highlight of the day was our Career Panel. A huge thank you to @nireynon.bsky.social, @aachinger.bsky.social, Luke Isbel and Dhanya Sooraj for sharing their insights, experiences, and advice. Your openness and encouragement were deeply appreciated by our EMCR community.
And congrats to.....
Sophie Navickas from @menzies-research.bsky.social for "Involvement of BRG1 in regulating the medulloblastoma epigenome"
Congrats Sophie!
Sophie Navickas from @menzies-research.bsky.social for "Involvement of BRG1 in regulating the medulloblastoma epigenome"
Congrats Sophie!
December 5, 2025 at 10:49 PM
And congrats to.....
Sophie Navickas from @menzies-research.bsky.social for "Involvement of BRG1 in regulating the medulloblastoma epigenome"
Congrats Sophie!
Sophie Navickas from @menzies-research.bsky.social for "Involvement of BRG1 in regulating the medulloblastoma epigenome"
Congrats Sophie!
Our next flash talk winner was 🥁
Sarah Williams from @garvaninstitute.bsky.social for "DNA methylation estimates of immune cell abundance have prognostic potential in triple negative breast cancer"
Congrats Sarah!
Sarah Williams from @garvaninstitute.bsky.social for "DNA methylation estimates of immune cell abundance have prognostic potential in triple negative breast cancer"
Congrats Sarah!
December 5, 2025 at 10:49 PM
Our next flash talk winner was 🥁
Sarah Williams from @garvaninstitute.bsky.social for "DNA methylation estimates of immune cell abundance have prognostic potential in triple negative breast cancer"
Congrats Sarah!
Sarah Williams from @garvaninstitute.bsky.social for "DNA methylation estimates of immune cell abundance have prognostic potential in triple negative breast cancer"
Congrats Sarah!
We had three winners of the flash talk session. The first is 🥁
Sarah Williams from @petermaccc.bsky.social for "Investigating how the maintenance of epithelial integrity prevents neoplastic tumours"
Congratulations Sarah!
Sarah Williams from @petermaccc.bsky.social for "Investigating how the maintenance of epithelial integrity prevents neoplastic tumours"
Congratulations Sarah!
December 5, 2025 at 10:49 PM
We had three winners of the flash talk session. The first is 🥁
Sarah Williams from @petermaccc.bsky.social for "Investigating how the maintenance of epithelial integrity prevents neoplastic tumours"
Congratulations Sarah!
Sarah Williams from @petermaccc.bsky.social for "Investigating how the maintenance of epithelial integrity prevents neoplastic tumours"
Congratulations Sarah!
We are thrilled to announce the winner of the short talks was
🏅 Jake Newland from @menzies-research.bsky.social for his talk "Differing modes of epigenetic repression in the Drosophila brain revealed by large-scale targeted DamID profiling and chromatin state analysis"
Congratulations Jake!
🏅 Jake Newland from @menzies-research.bsky.social for his talk "Differing modes of epigenetic repression in the Drosophila brain revealed by large-scale targeted DamID profiling and chromatin state analysis"
Congratulations Jake!
December 5, 2025 at 10:49 PM
We are thrilled to announce the winner of the short talks was
🏅 Jake Newland from @menzies-research.bsky.social for his talk "Differing modes of epigenetic repression in the Drosophila brain revealed by large-scale targeted DamID profiling and chromatin state analysis"
Congratulations Jake!
🏅 Jake Newland from @menzies-research.bsky.social for his talk "Differing modes of epigenetic repression in the Drosophila brain revealed by large-scale targeted DamID profiling and chromatin state analysis"
Congratulations Jake!
🧬 𝗦𝗵𝗼𝗿𝘁 & 𝗙𝗹𝗮𝘀𝗵 𝗧𝗮𝗹𝗸 𝗣𝗿𝗲𝘀𝗲𝗻𝘁𝗮𝘁𝗶𝗼𝗻𝘀
We heard an impressive series of short and flash talks from our AEpiA members from Melbourne, Sydney and Hobart in Austalian and Blenheim in New Zealand. Our presentation prizes were generously sponsored by NovogeneAIT Genomics!
We heard an impressive series of short and flash talks from our AEpiA members from Melbourne, Sydney and Hobart in Austalian and Blenheim in New Zealand. Our presentation prizes were generously sponsored by NovogeneAIT Genomics!
December 5, 2025 at 10:49 PM
🧬 𝗦𝗵𝗼𝗿𝘁 & 𝗙𝗹𝗮𝘀𝗵 𝗧𝗮𝗹𝗸 𝗣𝗿𝗲𝘀𝗲𝗻𝘁𝗮𝘁𝗶𝗼𝗻𝘀
We heard an impressive series of short and flash talks from our AEpiA members from Melbourne, Sydney and Hobart in Austalian and Blenheim in New Zealand. Our presentation prizes were generously sponsored by NovogeneAIT Genomics!
We heard an impressive series of short and flash talks from our AEpiA members from Melbourne, Sydney and Hobart in Austalian and Blenheim in New Zealand. Our presentation prizes were generously sponsored by NovogeneAIT Genomics!
If you’re planning to join us online, make sure you register before the deadline, the Zoom link will be sent only to registered attendees.
Secure your spot today 👉 www.aepia.org.au/emcr-symposium
We look forward to seeing you there!
Secure your spot today 👉 www.aepia.org.au/emcr-symposium
We look forward to seeing you there!
EMCR Symposium — Australasian Epigenetics Alliance
www.aepia.org.au
December 1, 2025 at 8:22 AM
If you’re planning to join us online, make sure you register before the deadline, the Zoom link will be sent only to registered attendees.
Secure your spot today 👉 www.aepia.org.au/emcr-symposium
We look forward to seeing you there!
Secure your spot today 👉 www.aepia.org.au/emcr-symposium
We look forward to seeing you there!
8/n
The Burr Lab is proudly supported by Snow Medical and the NHMRC.
#AEpiA #Epigenetics #LungCancer #CancerResearch #GeneRegulation
The Burr Lab is proudly supported by Snow Medical and the NHMRC.
#AEpiA #Epigenetics #LungCancer #CancerResearch #GeneRegulation
November 27, 2025 at 3:06 PM
8/n
The Burr Lab is proudly supported by Snow Medical and the NHMRC.
#AEpiA #Epigenetics #LungCancer #CancerResearch #GeneRegulation
The Burr Lab is proudly supported by Snow Medical and the NHMRC.
#AEpiA #Epigenetics #LungCancer #CancerResearch #GeneRegulation
7/n
This unique combination keeps the gene in a poised state, ready to switch on or off. In healthy cells, this allows flexibility during development. In cancer, this balance can be disrupted, leading to inappropriate switching of key genes that support tumour growth, survival, or immune evasion.
This unique combination keeps the gene in a poised state, ready to switch on or off. In healthy cells, this allows flexibility during development. In cancer, this balance can be disrupted, leading to inappropriate switching of key genes that support tumour growth, survival, or immune evasion.
November 27, 2025 at 3:06 PM
7/n
This unique combination keeps the gene in a poised state, ready to switch on or off. In healthy cells, this allows flexibility during development. In cancer, this balance can be disrupted, leading to inappropriate switching of key genes that support tumour growth, survival, or immune evasion.
This unique combination keeps the gene in a poised state, ready to switch on or off. In healthy cells, this allows flexibility during development. In cancer, this balance can be disrupted, leading to inappropriate switching of key genes that support tumour growth, survival, or immune evasion.
6/n
🧬 𝐖𝐡𝐚𝐭 𝐚𝐫𝐞 𝐛𝐢𝐯𝐚𝐥𝐞𝐧𝐭 𝐠𝐞𝐧𝐞𝐬?
Bivalent genes carry two opposing epigenetic marks on histones, the proteins DNA is wrapped around, at the same time:
H3K4me3, a mark linked to gene activation
H3K27me3, a mark linked to gene repression
🧬 𝐖𝐡𝐚𝐭 𝐚𝐫𝐞 𝐛𝐢𝐯𝐚𝐥𝐞𝐧𝐭 𝐠𝐞𝐧𝐞𝐬?
Bivalent genes carry two opposing epigenetic marks on histones, the proteins DNA is wrapped around, at the same time:
H3K4me3, a mark linked to gene activation
H3K27me3, a mark linked to gene repression
November 27, 2025 at 3:06 PM
6/n
🧬 𝐖𝐡𝐚𝐭 𝐚𝐫𝐞 𝐛𝐢𝐯𝐚𝐥𝐞𝐧𝐭 𝐠𝐞𝐧𝐞𝐬?
Bivalent genes carry two opposing epigenetic marks on histones, the proteins DNA is wrapped around, at the same time:
H3K4me3, a mark linked to gene activation
H3K27me3, a mark linked to gene repression
🧬 𝐖𝐡𝐚𝐭 𝐚𝐫𝐞 𝐛𝐢𝐯𝐚𝐥𝐞𝐧𝐭 𝐠𝐞𝐧𝐞𝐬?
Bivalent genes carry two opposing epigenetic marks on histones, the proteins DNA is wrapped around, at the same time:
H3K4me3, a mark linked to gene activation
H3K27me3, a mark linked to gene repression
5/n
This discovery positions Menin inhibitors as a promising new therapeutic strategy for SCLC. The Burr Lab is now working to translate these insights toward clinical trials, with the goal of bringing more effective and durable treatments to people affected by this aggressive cancer.
This discovery positions Menin inhibitors as a promising new therapeutic strategy for SCLC. The Burr Lab is now working to translate these insights toward clinical trials, with the goal of bringing more effective and durable treatments to people affected by this aggressive cancer.
November 27, 2025 at 3:06 PM
5/n
This discovery positions Menin inhibitors as a promising new therapeutic strategy for SCLC. The Burr Lab is now working to translate these insights toward clinical trials, with the goal of bringing more effective and durable treatments to people affected by this aggressive cancer.
This discovery positions Menin inhibitors as a promising new therapeutic strategy for SCLC. The Burr Lab is now working to translate these insights toward clinical trials, with the goal of bringing more effective and durable treatments to people affected by this aggressive cancer.
4/n
They found that blocking an epigenetic regulator called Menin can reset this faulty control, making cancer cells more visible to the immune system.
They found that blocking an epigenetic regulator called Menin can reset this faulty control, making cancer cells more visible to the immune system.
November 27, 2025 at 3:06 PM
4/n
They found that blocking an epigenetic regulator called Menin can reset this faulty control, making cancer cells more visible to the immune system.
They found that blocking an epigenetic regulator called Menin can reset this faulty control, making cancer cells more visible to the immune system.
3/n
In a 2023 Nature Cell Biology study (www.nature.com/articles/s41...), the team uncovered how a special class of genes known as bivalent genes are misregulated in small cell lung cancer (SCLC).
In a 2023 Nature Cell Biology study (www.nature.com/articles/s41...), the team uncovered how a special class of genes known as bivalent genes are misregulated in small cell lung cancer (SCLC).
Targeting Menin disrupts the KMT2A/B and polycomb balance to paradoxically activate bivalent genes - Nature Cell Biology
With whole-genome screens using a bivalent MHC class I gene expression readout, Sparbier et al. identify opposing roles for Menin and KMT2A/B in modulating activating H3K4me3 versus repressive H3K27me...
www.nature.com
November 27, 2025 at 3:06 PM
3/n
In a 2023 Nature Cell Biology study (www.nature.com/articles/s41...), the team uncovered how a special class of genes known as bivalent genes are misregulated in small cell lung cancer (SCLC).
In a 2023 Nature Cell Biology study (www.nature.com/articles/s41...), the team uncovered how a special class of genes known as bivalent genes are misregulated in small cell lung cancer (SCLC).
2/n
Understanding why cancers evade the immune system is one of the biggest challenges in developing effective therapies. The @burrlab.bsky.social at the @jcsmr.bsky.social, ANU, is working to understand the epigenetic mechanisms that allow lung cancer cells to support their survival
Understanding why cancers evade the immune system is one of the biggest challenges in developing effective therapies. The @burrlab.bsky.social at the @jcsmr.bsky.social, ANU, is working to understand the epigenetic mechanisms that allow lung cancer cells to support their survival
HOME | BurrLab
www.burrlab.com
November 27, 2025 at 3:06 PM
2/n
Understanding why cancers evade the immune system is one of the biggest challenges in developing effective therapies. The @burrlab.bsky.social at the @jcsmr.bsky.social, ANU, is working to understand the epigenetic mechanisms that allow lung cancer cells to support their survival
Understanding why cancers evade the immune system is one of the biggest challenges in developing effective therapies. The @burrlab.bsky.social at the @jcsmr.bsky.social, ANU, is working to understand the epigenetic mechanisms that allow lung cancer cells to support their survival