Miguel 💻🧬
@ahmig.es
110 followers 99 following 11 posts
bioinformatician, predoc researcher and PhD candidate @pathogenomics.bsky.social (@i2sysbio.es) | SARS-CoV-2 evolution and metabolic reconstruction of pathogens biotech BSc USAL & bioinfo MSc @uv.es 💻 github.com/ahmig | ahmig.es 📍 València, Spain
Posts Media Videos Starter Packs
ahmig.es
VIPERA v1.2.2 is out!! 🐍

now you can swap in different stats (useful for non-linear allele freq trends). also: new Docker images on release, containerized CI, updated envs, and minor bug fixes for smoother, reproducible intra-patient SARS-CoV-2 analyses

🧪👉 github.com/PathoGenOmics-Lab/VIPERA
GitHub - PathoGenOmics-Lab/VIPERA: A Snakemake workflow for SARS-CoV-2 Viral Intra-Patient Evolution Reporting and Analysis
A Snakemake workflow for SARS-CoV-2 Viral Intra-Patient Evolution Reporting and Analysis - PathoGenOmics-Lab/VIPERA
github.com
Reposted by Miguel 💻🧬
asteroiddave.bsky.social
FACT THREAD on New Interstellar Object #A11pl3Z

This story unfolded pretty fast yesterday for a few reasons. The object was discovered on July 1st UTC by the Asteroid Terrestrial-impact Last Alert System, or ATLAS team. A #NASA funded survey at the University of Hawaii. atlas.fallingstar.com 🔭🧪
Orbit diagram of interstellar object A11pl3Z
Reposted by Miguel 💻🧬
astrafoxen.bsky.social
So uh, there's a new interstellar object discovered at Chile yesterday. Name is A11pl3Z, has a hyperbolic trajectory of eccentricity 14±4 (WTF). Currently appmag 18, 4 AU away from Earth, and coming to 2 AU perihelion this October.
(tagging🔭☄️)
Observing it with remote scope rn, calling astronomers..
Pseudo-MPEC for A11pl3Z
projectpluto.com
Reposted by Miguel 💻🧬
i2sysbio.es
On June 20, #I2SysBio (@csic.es - @uv.es) hosted Alva Saa from association PRISMA, who shared ten key measures to foster #LGTBIQA+ 🏳️‍🌈 inclusion in #science. The talk addressed actions like staff training, safe reporting channels, and collective visibility in research.
🌐 i2sysbio.es/communicatio...
ahmig.es
VIPERA v1.2.1 is here!! 🐍🐍🐍

Our workflow for SARS-CoV-2 intra-patient evolution analysis now fully supports Snakemake 8/9 (with dedicated CI tests), BIONJ trees, richer reports, added config parameters, modular Snakefiles and more! 🧪👉 github.com/PathoGenOmics-Lab/VIPERA
GitHub - PathoGenOmics-Lab/VIPERA: A Snakemake workflow for SARS-CoV-2 Viral Intra-Patient Evolution Reporting and Analysis
A Snakemake workflow for SARS-CoV-2 Viral Intra-Patient Evolution Reporting and Analysis - PathoGenOmics-Lab/VIPERA
github.com
ahmig.es
Just back from MCEB 2025 in Granada! I presented our year-long work expanding VIPERA🐍 to help us better track pathogen evolution, here at @pathogenomics.bsky.social - @i2sysbio.bsky.social. I learned so much and returned full of ideas! Thanks to @bcbhubcsic.bsky.social for funding my attendance! 🧪
A photo of a group of people with the Alhambra in the back
Reposted by Miguel 💻🧬
mikeliturriaga.bsky.social
Gentes de Bluesky, firmad esto que es importante: iniciativa ciudadana europea para prohibir las "terapias" de conversión de personas LGTBIQ+. NO es un change.org, puede suponer un cambio legal real. Y no lo dejéis para luego, que se acaba el sábado. eci.ec.europa.eu/043/public/#...
European Citizens' Initiative
Give your support !
eci.ec.europa.eu
ahmig.es
🐥 #birdwatching #birds
fotografía de buitre leonado fotografía de buitre leonado fotografía de buitre leonado
Reposted by Miguel 💻🧬
dicv.csic.es
Un equipo liderado por el @i2sysbio.bsky.social publica una investigación que halla errores en las secuencias genéticas del #coronavirus incluidas en la mayor base de datos mundial. También participan @ibv-csic.bsky.social y el IIS La Fe.

delegacion.comunitatvalenciana.csic.es/hallan-error...
Un equipo multidisciplinar liderado por el Instituto de Biología Integrativa de Sistemas (I2SysBio), centro mixto del Consejo Superior de Investigaciones Científicas (CSIC) y la Universitat de València (UV), acaba de publicar un estudio que descubre una nueva perspectiva sobre la capacidad del virus SARS-CoV-2 para mutar e infectar a los humanos. Mediante una revisión de la base de datos genéticos del virus más utilizada durante la pandemia, el equipo de investigación halló ‘falsos positivos’ en su capacidad de reparación de las deleciones, un proceso que restaura secciones del genoma viral que afecta la capacidad del virus para replicarse o evadir el sistema inmunológico del huésped. En el trabajo, publicado en la revista Virus Evolution, participan investigadores del Instituto de Biomedicina de Valencia (IBV) del CSIC y del Instituto de Investigación Sanitaria La Fe (IIS-La Fe).

El trabajo liderado por el grupo de Patogenómica del I2SysBio en colaboración con el grupo de Biología Viral del mismo instituto ofrece una perspectiva innovadora sobre ciertos cambios genéticos raros en la proteína spike del SARS-CoV-2, la ‘llave’ que utiliza el coronavirus para infectar nuestras células. La investigación se centró en los llamados eventos de reparación de deleciones en esta proteína, en los que el virus aparenta corregir su genoma.
Reposted by Miguel 💻🧬
i2sysbio.es
By mining GISAID, researchers from I2SysBio uncover sequencing artifacts in SARS-CoV-2. Many repair mutations in the spike protein were due to errors in data processing. #covid19 #viruses #microsky🧪🦠💻🧬 More info: www.i2sysbio.es/communicatio... ⬇️
ahmig.es
happy to share our new study! 🧪

while exploring how often #sars-cov-2 "repairs" deletions in BA.1, we found significant genome artifacts in GISAID 🤯 we compared with raw reads from ENA + tested the effects in vitro. turns out, data processing matters a lot 📉

check it out!! doi.org/10.1093/ve/v...
Genome data artifacts and functional studies of deletion repair in the BA.1 SARS-CoV-2 spike protein
Abstract. Mutations within the N-terminal domain (NTD) of the spike (S) protein are critical for the emergence of successful SARS-CoV-2 viral lineages. The
doi.org
Reposted by Miguel 💻🧬
i2sysbio.es
Oferta de beca de investigación en nuestro instituto con la excelente supervisora Mireia Coscollá @pathogenomics.bsky.social . Proyecto enfocado en bioinformática, tema patógenos 🧪🦠🧫🧬🖥👩‍🔬
pathogenomics.bsky.social
HubBCB-01 @CSIC.es. Impacto del microbioma respiratorio humano en la introducción de un nuevo patógeno. IP Mireia Coscolla (I2SYSBIO, Valencia) Cinco meses, cinco mensualidades de 600€, 20 horas/semana. Nota media de grado al menos 7. Si grado terminado, matriculado master bioinformática o similar.
Reposted by Miguel 💻🧬
i2sysbio.es
Our institute hosts the exhibition “Train the feminist gaze”, promoted by the City Council of Valencia @ajuntament-vlc.bsky.social to highlight the inequalities between women and men present in everyday life and in areas such as art or science 🧪 www.i2sysbio.es/communicatio... #WomenInSTEM 👩‍🔬
Reposted by Miguel 💻🧬
i2sysbio.es
Our research institute I2SysBio🇪🇸 has created a starter pack for researchers in systems biology, everybody is welcome, write us if you want to be added 🔬🧫🧬🖥🦑🦠🌱🦟🪳🪸🌾
ahmig.es
Had a great time sharing an exciting new direction for VIPERA🐍 at the I congress of the Spanish Society of Bioinformatics and Computational Biology (SEBiBC)! Can't wait for the next one 🗣️🗣️
a picture taken during my flash talk about large-scale data analysis based on our tool, VIPERA (Viral Intra-Patient Evolution Reporting and Analysis), at the I SEBiBC congress