Matt Endrizzi
@aime2solve.bsky.social
Curious about ecotrons. Comparativebiospheromics.org
How can we know genetically engineered microbes work and are safe outside labs? Some buzzwords for the near future:
-Environmental Galenics
-Comparative Biospheromics
-Ecotrons
doi.org/10.1098/rstb...
-Environmental Galenics
-Comparative Biospheromics
-Ecotrons
doi.org/10.1098/rstb...
Environmental Galenics: large-scale fortification of extant microbiomes with engineered bioremediation agents | Philosophical Transactions of the Royal Society B: Biological Sciences
Contemporary synthetic biology-based biotechnologies are generating tools and strategies
for reprogramming genomes for specific purposes, including improvement and/or creation
of microbial processes f...
doi.org
October 30, 2025 at 4:26 PM
How can we know genetically engineered microbes work and are safe outside labs? Some buzzwords for the near future:
-Environmental Galenics
-Comparative Biospheromics
-Ecotrons
doi.org/10.1098/rstb...
-Environmental Galenics
-Comparative Biospheromics
-Ecotrons
doi.org/10.1098/rstb...
Biosafety has long been self-policed. While practical, it can raise concerns about conflicts of interest. The Comparative Biospheromics Network is advancing transparent, inclusive oversight to build trust, avoid backlash, and support a strong SynBio economy. Comparativebiospheromics.org
Comparative Biospheromics Network
Scalable, ecosystem-scale biosafety testing infrastructure for resilient innovation.
Comparativebiospheromics.org
August 9, 2025 at 10:08 PM
Biosafety has long been self-policed. While practical, it can raise concerns about conflicts of interest. The Comparative Biospheromics Network is advancing transparent, inclusive oversight to build trust, avoid backlash, and support a strong SynBio economy. Comparativebiospheromics.org
Put it in an ecotron with plastic waste.
Wow: Plastic → Tylenol? 🧪♻️💊
A biocompatible Lossen rearrangement—a reaction never seen in nature—occurring INSIDE E. coli
Bacteria engineered to convert PET plastic → Tylenol in <24h, with 92% yield + low emissions
Stunning blend of chemistry and synthetic biology
www.nature.com/articles/s41...
A biocompatible Lossen rearrangement—a reaction never seen in nature—occurring INSIDE E. coli
Bacteria engineered to convert PET plastic → Tylenol in <24h, with 92% yield + low emissions
Stunning blend of chemistry and synthetic biology
www.nature.com/articles/s41...
A biocompatible Lossen rearrangement in Escherichia coli - Nature Chemistry
Biocompatible chemistry merges chemo-catalytic reactions with cellular metabolism for sustainable small-molecule synthesis. Now a biocompatible Lossen rearrangement has been demonstrated to control ba...
www.nature.com
June 28, 2025 at 2:43 AM
Put it in an ecotron with plastic waste.
🎸Mom you gotta get my iPhone
Gotta get it after school
Get it from the principal
Gotta get it after school
From the principal
After school
From the principal
After school
From the principal…
After school.
Gotta get it after school
Get it from the principal
Gotta get it after school
From the principal
After school
From the principal
After school
From the principal…
After school.
June 28, 2025 at 2:28 AM
🎸Mom you gotta get my iPhone
Gotta get it after school
Get it from the principal
Gotta get it after school
From the principal
After school
From the principal
After school
From the principal…
After school.
Gotta get it after school
Get it from the principal
Gotta get it after school
From the principal
After school
From the principal
After school
From the principal…
After school.
Synthetic biology has so much potential to replace environmentally harmful industries and remediate pollution. Ecotrons - closed ecosystem models - will be essential to garner public support.
pmc.ncbi.nlm.nih.gov/articles/PMC...
pmc.ncbi.nlm.nih.gov/articles/PMC...
Ecotrons: Powerful and versatile ecosystem analysers for ecology, agronomy and environmental science
Ecosystems integrity and services are threatened by anthropogenic global changes. Mitigating and adapting to these changes require knowledge of ecosystem functioning in the expected novel environments...
pmc.ncbi.nlm.nih.gov
May 31, 2025 at 2:07 AM
Synthetic biology has so much potential to replace environmentally harmful industries and remediate pollution. Ecotrons - closed ecosystem models - will be essential to garner public support.
pmc.ncbi.nlm.nih.gov/articles/PMC...
pmc.ncbi.nlm.nih.gov/articles/PMC...
Here’s a data dashboard that allows you to analyze some of the results from the SPRUCE project - a DOE study of how peatlands respond to climate change factors. Could be fun for a high school science class. aime2solve.github.io/SPRUCE/
Comparative Biospheromics Dashboard
aime2solve.github.io
April 10, 2025 at 9:58 PM
Here’s a data dashboard that allows you to analyze some of the results from the SPRUCE project - a DOE study of how peatlands respond to climate change factors. Could be fun for a high school science class. aime2solve.github.io/SPRUCE/