ajmonteith.bsky.social
Andrew Monteith
@ajmonteith.bsky.social
97 followers 120 following 4 posts
Exploring the delicate balance between metabolic and inflammatory processes in disease. @UTKmicrobiology. Views my own.
Posts Media Videos Starter Packs
Reposted by Andrew Monteith
cbibberson.bsky.social
Carolyn Ibberson @cbibberson.bsky.social · Aug 4
Excited to have our new mini review on Microbiome Metabolism out today in I&I as part of the @asm.org New Voices in Microbiology collection! Check it out!

🧫🧪

journals.asm.org/doi/10.1128/...
Infections as ecosystems: community metabolic interactions in microbial pathogenesis | Infection and Immunity
Microbial communities are present on nearly every surface of the human body. These microbiomes exist as dynamic ecosystems that are influenced by heterogeneous nutritional and chemical landscapes, the...
journals.asm.org
1 17 40
Reposted by Andrew Monteith
francisalonzo12.bsky.social
Francis Alonzo @francisalonzo12.bsky.social · Aug 1
Happy to share Iván’s first-author pub from the lab! www.cell.com/cell-reports...
Staphylococcus aureus exploits lipoic acid salvage to combat host oxidative stress
Acosta et al. find that ADP-ribosylation of the lipoic acid carrier protein GcvH-L promotes Staphylococcus aureus resistance to oxidative burst and facilitates infection. ADP-ribosylation leads to a s...
www.cell.com
4 17 40
ajmonteith.bsky.social
Andrew Monteith @ajmonteith.bsky.social · Jul 7
Just out in Infection and Immunity!
Our latest review explores how neutrophils balance antimicrobial defense with tissue protection during infection, with a focus on metabolic signaling and NETs.
Read it here: journals.asm.org/doi/full/10....
#neutrophils #immunometabolism #NETosis #hostpathogen
Live fast, die young: neutrophils streamline their metabolism to maximize inflammation | Infection and Immunity
Cell metabolism plays a key role in shaping immune cell differentiation and function, with each immune cell subset depending on distinct metabolic pathways. While there have been extensive studies and...
journals.asm.org
1 2
ajmonteith.bsky.social
Andrew Monteith @ajmonteith.bsky.social · Feb 28
A successful collaboration across borders, and hopefully, the first of many!
1
ajmonteith.bsky.social
Andrew Monteith @ajmonteith.bsky.social · Feb 28
Happy you were willing to help us! Looking forward to our next multi-lab collaboration here at @utkmicrobiology.bsky.social
1
ajmonteith.bsky.social
Andrew Monteith @ajmonteith.bsky.social · Feb 27
The debut paper from the lab is live! Check out the amazing work by @ashleydwise.bsky.social and collaborators discovering that mitochondria are not just the 'powerhouse of the cell' but adapted by neutrophils to sense bacterial persistence and trigger NETosis.

www.cell.com/cell-host-mi...
Mitochondria sense bacterial lactate and drive release of neutrophil extracellular traps
Historically, neutrophil mitochondria were overlooked as they do not contribute to energy homeostasis. Wise et al. reveal that neutrophil mitochondria can sense bacterial persistence in the phagosome ...
www.cell.com
4 5
Reposted by Andrew Monteith
bconlon.bsky.social
Conlon Lab @bconlon.bsky.social · Feb 13
Delighted to share our new study. A collaboration with the Thurlow lab. Antibiotic resistance rapidly emerges and thrives in diabetic mice. A worrying coming together of two major and growing health problems worldwide www.science.org/doi/10.1126/...
Diabetes potentiates the emergence and expansion of antibiotic resistance
Diabetic infections are a reservoir for the emergence and proliferation of antibiotic resistance in Staphylococcus aureus.
www.science.org
1 21 47