Alessandra Carbone
@alecarbone.bsky.social
15 followers 7 following 5 posts
Computational Biology @sorbonneuniversite.bsky.social - Protein Sequences in Structure/Function/Classification, Genome Structure, Ancient Genomes & Geometry of Logical Reasoning
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alecarbone.bsky.social
We connected molecular signatures of selection with their mechanistic and functional relevance opening new ways of guiding experimental assays without requiring exhaustive testing of tens or hundreds of candidates.
Read in Molecular Biology and Evolution: academic.oup.com/mbe/advance-...
alecarbone.bsky.social
Designing a functional switch? We recoded a function of Chlamydomonas reinhardtii thioredoxin type-h into a photosynthetic type-f by switching selectivity determinants. Soon out in Frontiers in Plant Science: lnkd.in/emVPNHHa
with Julien Henri, Stephane Lemaire, Gianluca Lombardi and Andrea Mancini.
alecarbone.bsky.social
Diversifying disorders by distinguishing intrinsic and soft disorders, improves our understanding of proteins. See our new preprint on "LoRA-DR-suite: adapted embeddings predict intrinsic and soft disorder from protein sequences" - lnkd.in/esSD3qxq work done with Beatriz Seoane and Gianluca Lombardi
alecarbone.bsky.social
Postdoc position on Al-Driven Discovery of Next-Gen Antibiotics. Join my team! Please, forward it. hashtag#AI hashtag#MachineLearningandAI hashtag#Artificialintelligence hashtag#MachineLearning hashtag#protein