Alessio Buccino
@alessio-buccino.bsky.social
Electrophysiology tools, open source software, spike sorting, HD-MEAs and neuroengineering 🧠
6/8 Benchmarking confirms Kilosort4 > Kilosort2.5 in accuracy, precision, and recall—especially for low-SNR units—while recovering more complete spike trains.
December 9, 2025 at 9:21 AM
6/8 Benchmarking confirms Kilosort4 > Kilosort2.5 in accuracy, precision, and recall—especially for low-SNR units—while recovering more complete spike trains.
5/8 We also introduce a benchmarking pipeline that generates hybrid ground-truth data with drift-aware template injection, enabling rigorous, scalable comparison of sorting and preprocessing algorithms.
December 9, 2025 at 9:21 AM
5/8 We also introduce a benchmarking pipeline that generates hybrid ground-truth data with drift-aware template injection, enabling rigorous, scalable comparison of sorting and preprocessing algorithms.
3/8 The workflow includes: preprocessing (phase shift, filtering, denoising, drift estimation), spike sorting (Kilosort4/2.5 or SpyKING CIRCUS2 - and more options to come!), postprocessing, automated curation (quality metrics + UnitRefine), QC visualizations, and NWB export.
December 9, 2025 at 9:21 AM
3/8 The workflow includes: preprocessing (phase shift, filtering, denoising, drift estimation), spike sorting (Kilosort4/2.5 or SpyKING CIRCUS2 - and more options to come!), postprocessing, automated curation (quality metrics + UnitRefine), QC visualizations, and NWB export.