Alysa Kasen
@alysa-kasen.bsky.social
Reposted by Alysa Kasen
A study by @mxhend.bsky.social and collaborators found that an unstructured layer surrounding the Alzheimer’s-related protein tau plays a critical role in recruiting other proteins to misfold in Alzheimer’s progression. The findings were published in @natcomms.nature.com. www.vai.org/article/not-...
Not just a harmless accessory, tau’s ‘fuzzy coat’ contributes to Alzheimer’s progression – Van Andel Institute
Read about Not just a harmless accessory, tau’s ‘fuzzy coat’ contributes to Alzheimer’s progression on Van Andel Institute – Stay updated on the latest research and groundbreaking discoveries in scien...
www.vai.org
October 28, 2025 at 8:10 PM
A study by @mxhend.bsky.social and collaborators found that an unstructured layer surrounding the Alzheimer’s-related protein tau plays a critical role in recruiting other proteins to misfold in Alzheimer’s progression. The findings were published in @natcomms.nature.com. www.vai.org/article/not-...
I am happy to share that my doctoral work is now published in Nature Communications. I am grateful to all of the incredible scientists who contributed to this work.
Seed structure and phosphorylation in the fuzzy coat impact tau seeding competency - Nature Communications
Tau misfolds in Alzheimer’s disease, but how the link between tau filament structure and pathogenicity is unclear. This study shows that both filament core structure and phosphorylation in the fuzzy c...
www.nature.com
October 19, 2025 at 1:05 AM
I am happy to share that my doctoral work is now published in Nature Communications. I am grateful to all of the incredible scientists who contributed to this work.
I am excited to share that I have successfully defended my dissertation!
I am so greatful to my mentor, Dr. Mike Henderson, my Thesis Advisory Committee, our collaborators, and the members of the Henderson Lab who all helped me reach this milestone.
I am so greatful to my mentor, Dr. Mike Henderson, my Thesis Advisory Committee, our collaborators, and the members of the Henderson Lab who all helped me reach this milestone.
July 23, 2025 at 1:48 AM
I am excited to share that I have successfully defended my dissertation!
I am so greatful to my mentor, Dr. Mike Henderson, my Thesis Advisory Committee, our collaborators, and the members of the Henderson Lab who all helped me reach this milestone.
I am so greatful to my mentor, Dr. Mike Henderson, my Thesis Advisory Committee, our collaborators, and the members of the Henderson Lab who all helped me reach this milestone.
Reposted by Alysa Kasen
Seed structure and phosphorylation in the fuzzy coat impact tau seeding competency https://www.biorxiv.org/content/10.1101/2025.03.07.642026v1
March 10, 2025 at 7:16 PM
Seed structure and phosphorylation in the fuzzy coat impact tau seeding competency https://www.biorxiv.org/content/10.1101/2025.03.07.642026v1
I am very excited to share the pre-print containing a majority of my dissertation work.
Seed structure and phosphorylation in the fuzzy coat impact tau seeding competency
Tau is a pathogenic protein in Alzheimer's (AD) and other neurodegenerative diseases. The misfolding of tau into beta-sheet rich elongated filaments is thought to be a key event in disease pathogenesi...
www.biorxiv.org
March 12, 2025 at 2:00 AM
I am very excited to share the pre-print containing a majority of my dissertation work.
Reposted by Alysa Kasen
Another first place poster prize for graduate student @alysa-kasen.bsky.social for her work on tau pathology seeding! She is finishing up this summer and looking for a postdoc if anyone needs an excellent scientist!
February 26, 2025 at 7:47 PM
Another first place poster prize for graduate student @alysa-kasen.bsky.social for her work on tau pathology seeding! She is finishing up this summer and looking for a postdoc if anyone needs an excellent scientist!