André Marques
@amarques.bsky.social
A lover of chromosome biology 🧬🔬🔎 Studying (not only) meiosis, centromeres & genome evolution in plants!
Group leader at MPI for Plant Breeding Research in Cologne, Germany
Lab website:
https://www.mpipz.mpg.de/5028512/marques
Group leader at MPI for Plant Breeding Research in Cologne, Germany
Lab website:
https://www.mpipz.mpg.de/5028512/marques
📢 Three new #bioRxiv preprints from our team on holocentric chromosomes.
Together, they connect centromere repeat evolution, karyotype dynamics, and meiotic recombination outcomes, revealing how holocentric genomes evolve and function. 🧬👇
Together, they connect centromere repeat evolution, karyotype dynamics, and meiotic recombination outcomes, revealing how holocentric genomes evolve and function. 🧬👇
January 21, 2026 at 2:45 PM
📢 Three new #bioRxiv preprints from our team on holocentric chromosomes.
Together, they connect centromere repeat evolution, karyotype dynamics, and meiotic recombination outcomes, revealing how holocentric genomes evolve and function. 🧬👇
Together, they connect centromere repeat evolution, karyotype dynamics, and meiotic recombination outcomes, revealing how holocentric genomes evolve and function. 🧬👇
🌿🚗 Between 29 Jul–12 Aug we covered more than 2,000 km across Northeast Brazil on an unforgettable plant collection trip. Huge thanks to my PhD student Ruiyi and collaborators Profs. André Vanzela & Leonardo P. Felix—great teamwork, inspiring science, and breathtaking biodiversity! 🌱
#plantscience
#plantscience
August 21, 2025 at 1:44 PM
🌿🚗 Between 29 Jul–12 Aug we covered more than 2,000 km across Northeast Brazil on an unforgettable plant collection trip. Huge thanks to my PhD student Ruiyi and collaborators Profs. André Vanzela & Leonardo P. Felix—great teamwork, inspiring science, and breathtaking biodiversity! 🌱
#plantscience
#plantscience
Celebrating with our traditional paper cake! 📄🍰🌹
July 3, 2025 at 12:54 PM
Celebrating with our traditional paper cake! 📄🍰🌹
I am super happy to see our dog rose's paper featuring the cover of the July 3rd issue of @nature.com
read more here: tinyurl.com/dog-rose
read more here: tinyurl.com/dog-rose
July 2, 2025 at 5:10 PM
I am super happy to see our dog rose's paper featuring the cover of the July 3rd issue of @nature.com
read more here: tinyurl.com/dog-rose
read more here: tinyurl.com/dog-rose
7/7 Finally, we propose a surprising role of centromere bimodality in shaping the unique reproductive strategy of dogroses. This may represent a rare case of an obligate drive mechanism, functioning in a “drive or die” manner to maximize the transmission of univalents.
June 18, 2025 at 3:34 PM
7/7 Finally, we propose a surprising role of centromere bimodality in shaping the unique reproductive strategy of dogroses. This may represent a rare case of an obligate drive mechanism, functioning in a “drive or die” manner to maximize the transmission of univalents.
6/7 Using high resolution microscopy we reveal the contrasting dynamics of bivalent and univalent centromeres during male meiosis in dogroses, which produces haploid pollen through selective segregation of bivalent-forming chromosomes, while univalents lag and are eliminated.
June 18, 2025 at 3:34 PM
6/7 Using high resolution microscopy we reveal the contrasting dynamics of bivalent and univalent centromeres during male meiosis in dogroses, which produces haploid pollen through selective segregation of bivalent-forming chromosomes, while univalents lag and are eliminated.
5/7 Remarkably, we found a strong correlation of centromere type and size with the chromosome fates in meiosis. Thus, revealing a centromere warfare: bivalents use retrotransposon-rich centromeres; univalents deploy large satellite repeats to likely hijack egg cells.
June 18, 2025 at 3:34 PM
5/7 Remarkably, we found a strong correlation of centromere type and size with the chromosome fates in meiosis. Thus, revealing a centromere warfare: bivalents use retrotransposon-rich centromeres; univalents deploy large satellite repeats to likely hijack egg cells.
4/7 Using pollen sequencing, we show that bivalent-forming chromosomes can be composed by different subgenomes in different dogroses, supporting their multiple origins. We also show that dogrose offspring resemble the paternal genotype confirming their asymmetric inheritance.
June 18, 2025 at 3:34 PM
4/7 Using pollen sequencing, we show that bivalent-forming chromosomes can be composed by different subgenomes in different dogroses, supporting their multiple origins. We also show that dogrose offspring resemble the paternal genotype confirming their asymmetric inheritance.
3/7 Haplotype-resolved genomes reveal that modern dogroses are composed by four distinct subgenomes, with one particular subgenome being present in two copies (bivalent-forming subgenome), while the remaining 3 chromosome sets are present in single copies (univalent subgenomes)
June 18, 2025 at 3:34 PM
3/7 Haplotype-resolved genomes reveal that modern dogroses are composed by four distinct subgenomes, with one particular subgenome being present in two copies (bivalent-forming subgenome), while the remaining 3 chromosome sets are present in single copies (univalent subgenomes)
1st holocentric chromosome conference rocking in Neuchâtel! @marcialescudero.bsky.social @holocentricity2025.bsky.social
April 25, 2025 at 12:27 PM
1st holocentric chromosome conference rocking in Neuchâtel! @marcialescudero.bsky.social @holocentricity2025.bsky.social
Burning 20% of my last BBQ calories' intake 🤣
April 12, 2025 at 6:56 AM
Burning 20% of my last BBQ calories' intake 🤣
Starting the season 🥩🍖
April 11, 2025 at 2:01 AM
Starting the season 🥩🍖
#8️⃣
Marques, A. and Drinnenberg, A. I. (2025). Same but different: Centromere regulations in holocentric insects and plants. Current Opinion in Cell Biology 93, 102484
doi.org/10.1016/j.ce...
Marques, A. and Drinnenberg, A. I. (2025). Same but different: Centromere regulations in holocentric insects and plants. Current Opinion in Cell Biology 93, 102484
doi.org/10.1016/j.ce...
February 21, 2025 at 10:12 AM
#8️⃣
Marques, A. and Drinnenberg, A. I. (2025). Same but different: Centromere regulations in holocentric insects and plants. Current Opinion in Cell Biology 93, 102484
doi.org/10.1016/j.ce...
Marques, A. and Drinnenberg, A. I. (2025). Same but different: Centromere regulations in holocentric insects and plants. Current Opinion in Cell Biology 93, 102484
doi.org/10.1016/j.ce...
I am thrilled to share our new review on holocentric chromosomes. It was a lot of fun to write it together with Ines Drinnenberg!
Same but different: Centromere regulations in holocentric insects and plants doi.org/10.1016/j.ce...
Same but different: Centromere regulations in holocentric insects and plants doi.org/10.1016/j.ce...
February 21, 2025 at 9:17 AM
I am thrilled to share our new review on holocentric chromosomes. It was a lot of fun to write it together with Ines Drinnenberg!
Same but different: Centromere regulations in holocentric insects and plants doi.org/10.1016/j.ce...
Same but different: Centromere regulations in holocentric insects and plants doi.org/10.1016/j.ce...
Traditional Snow group picture! In Cologne it only snow once a year so we have to be quick ☃️
January 9, 2025 at 1:55 PM
Traditional Snow group picture! In Cologne it only snow once a year so we have to be quick ☃️
Nice one just before the year turns again: academic.oup.com/aob/advance-...
December 26, 2024 at 9:31 AM
Nice one just before the year turns again: academic.oup.com/aob/advance-...
Enjoying a very nice Brazilian Feijoada with the lab today!
December 20, 2024 at 4:30 PM
Enjoying a very nice Brazilian Feijoada with the lab today!
This year, our group's Secret Santa 🎁🎄 activity began with a delightful guided tour exploring Cologne's history, complete with a festive touch of Christmas markets and a special dinner. I am thankful to all my group members for their patience with me 😅
December 6, 2024 at 8:43 AM
This year, our group's Secret Santa 🎁🎄 activity began with a delightful guided tour exploring Cologne's history, complete with a festive touch of Christmas markets and a special dinner. I am thankful to all my group members for their patience with me 😅
Nice seminar from @cristobaluauy.bsky.social about wheat spike development and lots of awesome spatial transcriptomics in our @ceplas.bsky.social Friday!
November 29, 2024 at 1:06 PM
Nice seminar from @cristobaluauy.bsky.social about wheat spike development and lots of awesome spatial transcriptomics in our @ceplas.bsky.social Friday!
Thanksgiving 🦃 dinner 🍽️ finally there 🤩
November 28, 2024 at 7:37 PM
Thanksgiving 🦃 dinner 🍽️ finally there 🤩
Keeping up with our lab Christmas 🎄 Eisstockschießen tradition!
November 28, 2024 at 7:21 PM
Keeping up with our lab Christmas 🎄 Eisstockschießen tradition!
If you see this, please repost with a favourite photo of the sky that you've taken recently.
November 16, 2024 at 9:25 AM
If you see this, please repost with a favourite photo of the sky that you've taken recently.
🔥𝑷𝒂𝒑𝒆𝒓 𝒂𝒍𝒆𝒓𝒕🔥
Thrilled 🤩to announce that our paper on 𝗺𝗲𝗶𝗼𝘁𝗶𝗰 𝗿𝗲𝗰𝗼𝗺𝗯𝗶𝗻𝗮𝘁𝗶𝗼𝗻 𝗱𝘆𝗻𝗮𝗺𝗶𝗰𝘀 𝗶𝗻 𝗵𝗼𝗹𝗼𝗰𝗲𝗻𝘁𝗿𝗶𝗰 𝗽𝗹𝗮𝗻𝘁𝘀 has now been officially published in @natureplants.bsky.social
DFG ERC_Research @ceplas.bsky.social @maxplanck.bsky.social
𝑳𝒊𝒏𝒌 𝒕𝒐 𝒕𝒉𝒆 𝒑𝒖𝒃𝒍𝒊𝒔𝒉𝒆𝒅 𝒗𝒆𝒓𝒔𝒊𝒐𝒏 𝒉𝒆𝒓𝒆: www.nature.com/articles/s41...
Thrilled 🤩to announce that our paper on 𝗺𝗲𝗶𝗼𝘁𝗶𝗰 𝗿𝗲𝗰𝗼𝗺𝗯𝗶𝗻𝗮𝘁𝗶𝗼𝗻 𝗱𝘆𝗻𝗮𝗺𝗶𝗰𝘀 𝗶𝗻 𝗵𝗼𝗹𝗼𝗰𝗲𝗻𝘁𝗿𝗶𝗰 𝗽𝗹𝗮𝗻𝘁𝘀 has now been officially published in @natureplants.bsky.social
DFG ERC_Research @ceplas.bsky.social @maxplanck.bsky.social
𝑳𝒊𝒏𝒌 𝒕𝒐 𝒕𝒉𝒆 𝒑𝒖𝒃𝒍𝒊𝒔𝒉𝒆𝒅 𝒗𝒆𝒓𝒔𝒊𝒐𝒏 𝒉𝒆𝒓𝒆: www.nature.com/articles/s41...
February 9, 2024 at 10:20 AM
🔥𝑷𝒂𝒑𝒆𝒓 𝒂𝒍𝒆𝒓𝒕🔥
Thrilled 🤩to announce that our paper on 𝗺𝗲𝗶𝗼𝘁𝗶𝗰 𝗿𝗲𝗰𝗼𝗺𝗯𝗶𝗻𝗮𝘁𝗶𝗼𝗻 𝗱𝘆𝗻𝗮𝗺𝗶𝗰𝘀 𝗶𝗻 𝗵𝗼𝗹𝗼𝗰𝗲𝗻𝘁𝗿𝗶𝗰 𝗽𝗹𝗮𝗻𝘁𝘀 has now been officially published in @natureplants.bsky.social
DFG ERC_Research @ceplas.bsky.social @maxplanck.bsky.social
𝑳𝒊𝒏𝒌 𝒕𝒐 𝒕𝒉𝒆 𝒑𝒖𝒃𝒍𝒊𝒔𝒉𝒆𝒅 𝒗𝒆𝒓𝒔𝒊𝒐𝒏 𝒉𝒆𝒓𝒆: www.nature.com/articles/s41...
Thrilled 🤩to announce that our paper on 𝗺𝗲𝗶𝗼𝘁𝗶𝗰 𝗿𝗲𝗰𝗼𝗺𝗯𝗶𝗻𝗮𝘁𝗶𝗼𝗻 𝗱𝘆𝗻𝗮𝗺𝗶𝗰𝘀 𝗶𝗻 𝗵𝗼𝗹𝗼𝗰𝗲𝗻𝘁𝗿𝗶𝗰 𝗽𝗹𝗮𝗻𝘁𝘀 has now been officially published in @natureplants.bsky.social
DFG ERC_Research @ceplas.bsky.social @maxplanck.bsky.social
𝑳𝒊𝒏𝒌 𝒕𝒐 𝒕𝒉𝒆 𝒑𝒖𝒃𝒍𝒊𝒔𝒉𝒆𝒅 𝒗𝒆𝒓𝒔𝒊𝒐𝒏 𝒉𝒆𝒓𝒆: www.nature.com/articles/s41...