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ambaln.bsky.social @ambaln.bsky.social · 5d

Our new BPD review is now on PubMed Central and so free to access: pmc.ncbi.nlm.nih.gov/articles/PMC...

The Evolving Pathophysiology of Bronchopulmonary Dysplasia

Bronchopulmonary dysplasia (BPD) is the most common morbidity in very preterm infants, and is characterized by abnormal development of the lung. The pathophysiology of BPD is primarily due to effects ...

pmc.ncbi.nlm.nih.gov

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Reposted

JAMA @jama.com · 8d

In extremely preterm infants, intratracheal budesonide mixed with surfactant did not reduce bronchopulmonary dysplasia or death by 36 weeks' postmenstrual age.

ja.ma/4738oYb

Infographic from JAMA comparing budesonide and surfactant vs surfactant alone for reducing bronchopulmonary dysplasia/death in preterm infants. It includes population data (320 male, 319 female), intervention details, and findings showing no significant difference between groups.

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ambaln.bsky.social @ambaln.bsky.social · 8d

Our BiB trial manuscript now published in JAMA...Early Intratracheal Budesonide for Bronchopulmonary Dysplasia url: jamanetwork.com/journals/jam...

Early Intratracheal Budesonide for Bronchopulmonary Dysplasia

This randomized clinical trial conducted at centers of the United States Neonatal Research Network assesses whether early intratracheal administration of a combination of budesonide mixed with surfact...

jamanetwork.com

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ambaln.bsky.social @ambaln.bsky.social · Sep 6

#neobluesky #neoEBM: Screening for BPD PH fn.bmj.com/content/earl...

Screening for pulmonary hypertension in preterm infants with bronchopulmonary dysplasia: when, how often and does it matter?

Objective Bronchopulmonary dysplasia (BPD) associated pulmonary hypertension (BPD-PH) is the most severe endotype of BPD; there is insufficient evidence to support the optimal screening strategy in at...

fn.bmj.com

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Kent Willis MD @kentwillismd.bsky.social · Aug 30

Our review of the evolving pathology of Bronchopulmonary dysplasia journals.physiology.org/doi/abs/10.1... #neosky #medky #science #lung #premiee

The Evolving Pathophysiology of Bronchopulmonary Dysplasia | Physiological Reviews | American Physiological Society

Bronchopulmonary dysplasia (BPD) is the most common morbidity in very preterm infants, and is characterized by abnormal development of the lung. The pathophysiology of BPD is primarily due to effects ...

journals.physiology.org

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Reposted

ATS Assemblies @ats-assemblies.bsky.social · Jul 15

📢 Join @ats-peds.bsky.social on Tue, July. 22 at 1PM ET!
Dr. Cindy McEvoy (OHSU) presents:
"Extended CPAP in Preterm Infants Increases Lung Growth at 6 Months: A RCT."

🩺Featuring a panel of experts + moderated discussion on clinical impact & future care.

🔗Register Now!

American Thoracic Society | Extended Continuous Positive Airway…

The American Thoracic Society is the world's leading medical society dedicated to accelerating the advancement of global respiratory health through…

site.thoracic.org

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Carlos del Río, MD, FACP, FIDSA @docdelrio.bsky.social · Jun 19

www.al.com/politics/202... “Academic Health Centers are like tropical rainforests: They take decades to develop and weeks to destroy.”

Only you can save Birmingham’s medical rainforest: op-ed from UAB researcher

he fuel that propels Academic Health Centers like UAB comes, in large part, from NIH funding.

www.al.com

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ambaln.bsky.social @ambaln.bsky.social · Jun 17

#neonatology...https://onlinelibrary.wiley.com/doi/10.1002/ppul.71165

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ambaln.bsky.social @ambaln.bsky.social · Jun 7

Nice work!

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ambaln.bsky.social @ambaln.bsky.social · Apr 29

#neobluesky #neoEBM #EBNEOalerts ...the new AAP Committee of Fetus and Newborn statement on the PDA: publications.aap.org/pediatrics/a...

Patent Ductus Arteriosus in Preterm Infants

Despite extensive research in basic science and in clinical settings with thousands of infants over decades, uncertainty and controversy persist regarding the significance, assessment, and management ...

publications.aap.org

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ambaln.bsky.social @ambaln.bsky.social · Apr 9

Our editorial on their paper in the ERJ: pubmed.ncbi.nlm.nih.gov/40180361/

More may be better: extended CPAP may help alveolar development - PubMed

More may be better: extended CPAP may help alveolar development

pubmed.ncbi.nlm.nih.gov

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ambaln.bsky.social @ambaln.bsky.social · Apr 8

Our new publication from the OBOE consortium: jamanetwork.com/journals/jam...

Antenatal Opioid Exposure and Global and Regional Brain Volumes in Newborns

This cohort study using data from the OBOE (Outcomes of Babies with Opioid Exposure) study compares global, regional, and tissue-specific brain volumes in opioid-exposed newborns vs unexposed controls...

jamanetwork.com

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ambaln.bsky.social @ambaln.bsky.social · Mar 20

From www.phdcomics.com. This is familiar to most trainees.

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ambaln.bsky.social @ambaln.bsky.social · Mar 13

#neosky, #neoEBM. Some results from the OBOE study: pubmed.ncbi.nlm.nih.gov/40057022/

Neurobehavioral Profiles in Opioid-Exposed and Unexposed Neonates - PubMed

Neonates with prenatal exposure to opioids and other psychotropic substances have distinctive patterns of neurobehavior. Additional follow-up is needed to determine if these neurobehavioral difference...

pubmed.ncbi.nlm.nih.gov

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Reposted

The Anatomical Record @anatrecord.bsky.social · Mar 10

We are pleased to announce a special issue, "Breathing at the interface of Anatomy and Physiology", in honor of our former Editor-in-Chief, Dr. Kurt Albertine. This volume celebrates his immense contributions to respiratory anatomy, physiology & neonatology.
buff.ly/r5XpcQR

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Reposted

Evidence-based Neonatology @ebneo.bsky.social · Mar 12

A single-site trial assesses the impact of early (days 4–7) vs. delayed (days 10–14) bovine-derived human milk fortification in preterm infants. buff.ly/9G6Mw0x

#ebneoalerts #neobluesky #neoEBM

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Reposted

Evidence-based Neonatology @ebneo.bsky.social · Mar 4

A prospective cohort in @AJOG_thegray examines the relationship between chorioamnionitis, funisitis, and cerebral palsy in infants born < 27 weeks #neobluesky #neoEBM #EBNEOalerts buff.ly/6AId56i

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ambaln.bsky.social @ambaln.bsky.social · Mar 3

Congratulations to Viral Jain !. Important work on funisitis and CP. pubmed.ncbi.nlm.nih.gov/40023378/

Funisitis Increases the Risk of Death or Cerebral Palsy in Extremely Preterm Infants - PubMed

Funisitis was associated with an increased risk of the combined outcome of death or cerebral palsy. In surviving infants, the direct adverse effects of funisitis appear to lead to cerebral palsy, inde...

pubmed.ncbi.nlm.nih.gov

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Ariel Salas @arielsalasmd.bsky.social · Feb 21

Our RCT combining early full enteral nutrition with early human milk fortification is now available online! The sustained effect on length suggests that this feeding practice is beneficial for very preterm infants #neonatalsky #neosky #neotwitter #neoebm

authors.elsevier.com/sd/article/S...

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Reposted

Nature Portfolio @natureportfolio.nature.com · Feb 16

A paper in Nature Methods presents Segment Anything for Microscopy, a tool for segmentation and tracking in multidimensional microscopy data. https://go.nature.com/3QiRonW

This is figure 1, which gives an overview of Segment Anything for Microscopy.

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ambaln.bsky.social @ambaln.bsky.social · Feb 6

#neosky, #neoEBM...Our new publication "Detection of pulmonary hypertension in preterm infants with bronchopulmonary dysplasia using oxygen saturation data": rdcu.be/d8NSy

Detection of pulmonary hypertension in preterm infants with bronchopulmonary dysplasia using oxygen saturation data

Pediatric Research - Detection of pulmonary hypertension in preterm infants with bronchopulmonary dysplasia using oxygen saturation data

rdcu.be

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Reposted

Nature Portfolio @natureportfolio.nature.com · Feb 6

Rock and dust samples brought back from the near-Earth asteroid Bennu contain organic matter, including amino acids and all five DNA and RNA nucleobases, according to two papers in Nature Astronomy and Nature.
https://go.nature.com/40SlwfF
https://go.nature.com/3CC6ZLO
🔭 🧪

This figure illustrates molecules and minerals discovered in samples of near-Earth asteroid Bennu, which were delivered to Earth by NASA’s OSIRIS-REx mission in September 2023. The upper left panel depicts precursor molecules like ammonia and formaldehyde, while the upper right depicts salts and clays. These early ingredients mixed with water inside the parent body to undergo chemical reactions and synthesize organic molecules, shown at bottom. The lower right panel depicts nucleobases, the genetic components of DNA and RNA, while the lower left depicts amino acids, the building blocks of proteins. The Bennu samples contain all five of the nucleobases that are found in DNA and RNA, and 14 of the 20 amino acids that life uses to build proteins. Credit: NASA

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Reposted

Kent Willis MD @kentwillismd.bsky.social · Jan 27

After 7 years of work and 1.5 years winding its way through publication, the paper I’ve wanted to share with you all for so long is finally out in @microbiomej.bsky.social

microbiomejournal.biomedcentral.com/articles/10....

#neosky #medsky #scisky #microbiome #fungi #mycobiome #newPI #science

The fungal microbiota modulate neonatal oxygen-induced lung injury - Microbiome

Background The immature lungs of very preterm infants are exposed to supraphysiologic oxygen, contributing to bronchopulmonary dysplasia (BPD), a chronic lung disease that is the most common morbidity...

microbiomejournal.biomedcentral.com

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ambaln.bsky.social @ambaln.bsky.social · Jan 27

#Neonatology....Congratulations to @kentwillismd.bsky.social : microbiomejournal.biomedcentral.com/articles/10....

The fungal microbiota modulate neonatal oxygen-induced lung injury - Microbiome

Background The immature lungs of very preterm infants are exposed to supraphysiologic oxygen, contributing to bronchopulmonary dysplasia (BPD), a chronic lung disease that is the most common morbidity...

microbiomejournal.biomedcentral.com

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