Chromatin labeling and imaging group
@andimaging.bsky.social
MPI for Multidisciplinary Sciences
Fluorescent #probes for live-cell #nanoscopy: #STED, #MINFLUX and #confocal. We do the job, all of you judge if it is useful!
Fluorescent #probes for live-cell #nanoscopy: #STED, #MINFLUX and #confocal. We do the job, all of you judge if it is useful!
Finally, our paper describing more rhodamine 4-isomers and >80 probes is out in @NatureComms : https://doi.org/10.1038/s41467-023-36913-2 Enjoy a four color live-cell dynamics of nucleus (magenta), mitochondria (cyan), lysosomes (yellow) and microtubules (gray). All stained with 4-isomers.
February 1, 2025 at 4:13 PM
Finally, our paper describing more rhodamine 4-isomers and >80 probes is out in @NatureComms : https://doi.org/10.1038/s41467-023-36913-2 Enjoy a four color live-cell dynamics of nucleus (magenta), mitochondria (cyan), lysosomes (yellow) and microtubules (gray). All stained with 4-isomers.
Label size is becoming an important issue in modern #fluorescence #microscopy or #nanoscopy. See size comparison of the commonly used tags and labeling approaches - antibody, GFP, Halo-tag, SNAP-tag, nanobody or small probe (5-610CP-Hoechst). Happy #FluorescenceFriday! #SciArt
February 1, 2025 at 4:12 PM
Label size is becoming an important issue in modern #fluorescence #microscopy or #nanoscopy. See size comparison of the commonly used tags and labeling approaches - antibody, GFP, Halo-tag, SNAP-tag, nanobody or small probe (5-610CP-Hoechst). Happy #FluorescenceFriday! #SciArt
Let's look at the molecular details of the tubulin probe's action. Enjoy computational model of the tubulin labeled with 4-TMR-LTX. The probe binds only to one subunit - beta-tubulin. Happy #FluorescenceFriday ! #SciArt #ChemTwitter #Fluorescence
February 1, 2025 at 4:12 PM
Let's look at the molecular details of the tubulin probe's action. Enjoy computational model of the tubulin labeled with 4-TMR-LTX. The probe binds only to one subunit - beta-tubulin. Happy #FluorescenceFriday ! #SciArt #ChemTwitter #Fluorescence
Rhodamines exist in two forms: Zwitterion (fluorescent) and Spirolactone (non-fluorescent). Zwitterion is hydrophilic and likes water, but Spirolactone is hydrophobic and keeps its tail out of water. See our visualization of these two forms and enjoy #FluorescenceFriday !!!
February 1, 2025 at 4:12 PM
Rhodamines exist in two forms: Zwitterion (fluorescent) and Spirolactone (non-fluorescent). Zwitterion is hydrophilic and likes water, but Spirolactone is hydrophobic and keeps its tail out of water. See our visualization of these two forms and enjoy #FluorescenceFriday !!!
Our group wish all of you Merry #Christmas and #HappyNewYear ! We wish all of you good health and peaceful cozy celebrations. Enjoy our postcard made of amazing structures which we observed in living cells. #AcademicTwitter #SciArt #FluorescenceFriday #Christmas2022
February 1, 2025 at 4:12 PM
Our group wish all of you Merry #Christmas and #HappyNewYear ! We wish all of you good health and peaceful cozy celebrations. Enjoy our postcard made of amazing structures which we observed in living cells. #AcademicTwitter #SciArt #FluorescenceFriday #Christmas2022
Live-cell imaging of EB3-GFP tagged is amazing. Enjoy and follow the plus ends of microtubules (yellow) in the network of tubulin (magenta). Happy #FluorescenceFriday ! #SciArt #ChemTwitter #Fluorescence
February 1, 2025 at 4:11 PM
Live-cell imaging of EB3-GFP tagged is amazing. Enjoy and follow the plus ends of microtubules (yellow) in the network of tubulin (magenta). Happy #FluorescenceFriday ! #SciArt #ChemTwitter #Fluorescence
Please RT ! We are looking for a seriously motivated #PhD student to join in 2023. Join us, if you are passionate about chromatin labeling and imaging using #STED and #MINFLUX microscopy! Apply to @IMPRS_GS: https://t.co/it4nFJ3OKb #AcademicTwitter #PhDposition #Research
February 1, 2025 at 4:11 PM
Please RT ! We are looking for a seriously motivated #PhD student to join in 2023. Join us, if you are passionate about chromatin labeling and imaging using #STED and #MINFLUX microscopy! Apply to @IMPRS_GS: https://t.co/it4nFJ3OKb #AcademicTwitter #PhDposition #Research
Live-cell imaging is extremely entertaining. Enjoy dancing mitochondria (orange) in the network of tubulin (yellow) and vimentin (cyan) next to the nucleus (green). Happy #FluorescenceFriday! #SciArt #ChemTwitter #Fluorescence
February 1, 2025 at 4:11 PM
Live-cell imaging is extremely entertaining. Enjoy dancing mitochondria (orange) in the network of tubulin (yellow) and vimentin (cyan) next to the nucleus (green). Happy #FluorescenceFriday! #SciArt #ChemTwitter #Fluorescence
Today we have made some rhodamine lava in a flask!!! Enjoy #FluorescenceFriday and have a nice weekend! #SciArt #ChemTwitter #Fluorescence
February 1, 2025 at 4:11 PM
Today we have made some rhodamine lava in a flask!!! Enjoy #FluorescenceFriday and have a nice weekend! #SciArt #ChemTwitter #Fluorescence
Back to #imaging and testing of lice-cell probes. #Centrosome and primary cilium in 3D #STED. Today is 11.11, and we wish you a happy #FluorescenceFriday ! #Science #SciArt #RealTimeChem #Chemtwitter
February 1, 2025 at 4:10 PM
Back to #imaging and testing of lice-cell probes. #Centrosome and primary cilium in 3D #STED. Today is 11.11, and we wish you a happy #FluorescenceFriday ! #Science #SciArt #RealTimeChem #Chemtwitter
Nice and glowing. Coumarin 6 is a derivative of one of the coumarin. Coumarins' chemical synthesis was started in 1868 by W. H. Perkin. #FluorescenceFriday #fluorescentfriday #Science #SciArt #RealTimeChem #Chemtwitter
February 1, 2025 at 4:10 PM
Nice and glowing. Coumarin 6 is a derivative of one of the coumarin. Coumarins' chemical synthesis was started in 1868 by W. H. Perkin. #FluorescenceFriday #fluorescentfriday #Science #SciArt #RealTimeChem #Chemtwitter
Sometimes chemical reactions can be very bright and glowing! Happy #FluorescenceFriday or #FluorescentFriday! #SciArt #GLOW #RealTimeChem #Chemtwitter
February 1, 2025 at 4:10 PM
Sometimes chemical reactions can be very bright and glowing! Happy #FluorescenceFriday or #FluorescentFriday! #SciArt #GLOW #RealTimeChem #Chemtwitter
We have a new #chemistry lab at @mpi_nat which is nice to use for the synthesis of fluorescent probes. Let's start #FluorescenceFriday ! Enjoy ! #biology #photography #imaging #sciart
February 1, 2025 at 4:10 PM
We have a new #chemistry lab at @mpi_nat which is nice to use for the synthesis of fluorescent probes. Let's start #FluorescenceFriday ! Enjoy ! #biology #photography #imaging #sciart
We started to work on imaging of mitochondria. They look nice and jumpy. Now we can understand our neighbors' and colleagues' passion from @JakobsLab Read more: https://www.biorxiv.org/content/10.1101/2022.06.13.495683v2
February 1, 2025 at 4:09 PM
We started to work on imaging of mitochondria. They look nice and jumpy. Now we can understand our neighbors' and colleagues' passion from @JakobsLab Read more: https://www.biorxiv.org/content/10.1101/2022.06.13.495683v2
New biocompatible probes for actin show more dynamics! We see not only F-actin, but also G-actin! Read more about old Jasplakinolide probes and their improved versions here: https://t.co/YnSjEljhiK and https://t.co/wtXaYnyXg0
February 1, 2025 at 4:09 PM
New biocompatible probes for actin show more dynamics! We see not only F-actin, but also G-actin! Read more about old Jasplakinolide probes and their improved versions here: https://t.co/YnSjEljhiK and https://t.co/wtXaYnyXg0