andreasmfritzen.bsky.social
@andreasmfritzen.bsky.social
Happy to be a part of this out now in @NatMetabolism: Dietary protein restriction elevates FGF21 levels and energy requirements to maintain body weight in lean men. Adding nuances to the discussion on dietary protein for body weight regulation and into FGF21 biology.
www.nature.com/articles/s42...
Dietary protein restriction elevates FGF21 levels and energy requirements to maintain body weight in lean men
Nature Metabolism - Dietary protein restriction in healthy, lean men elicits an increased energy intake to maintain body weight, which is driven, at least in part, by FGF21-mediated alterations to...
www.nature.com
March 10, 2025 at 9:08 AM
Reposted
Curious about muscle metabolism? 🚴‍♂️ We reveal PanK4 as a conserved exercise target in muscle! 💪 PanK4 regulates lipid & glucose use likely via acetyl-CoA. We think PanK4 belongs alongside Akt, mTOR, AMPK, Rac1 & more as a key player in muscle energy homeostasis. #Metabolism #MyoBlue
Pantothenate kinase 4 controls skeletal muscle substrate metabolism - Nature Communications
Here, Miranda-Cervantes et al. identified pantothenate kinase 4 (PanK4) as a key regulator of muscle metabolism. Deleting PanK4 impairs fatty acid oxidation and glucose uptake, leading to glucose into...
www.nature.com
January 6, 2025 at 2:44 PM