Andrew
@andrewfong.bsky.social
Reposted by Andrew
📚NEW #gdTcell PAPER ALERT! 'Microbiota promote enhanced CD39 expression in γδ intraepithelial lymphocytes through the activation of TCR and IL-15 signaling' is now out in @mucosalimmunol.bsky.social! #gastrosky #GIsky #IBDsky Join us for a Bluetorial 🧵...
Microbiota promote enhanced CD39 expression in γδ intraepithelial lymphocytes through the activation of TCR and IL-15 signaling
Intraepithelial lymphocytes expressing the γδ T cell receptor (γδ IEL) provide continuous surveillance of the intestinal epithelium. We report that mi…
www.sciencedirect.com
August 7, 2025 at 9:36 PM
📚NEW #gdTcell PAPER ALERT! 'Microbiota promote enhanced CD39 expression in γδ intraepithelial lymphocytes through the activation of TCR and IL-15 signaling' is now out in @mucosalimmunol.bsky.social! #gastrosky #GIsky #IBDsky Join us for a Bluetorial 🧵...
Reposted by Andrew
Congrats to @ananya-p.bsky.social on her outstanding Master’s defense on #gdTcell migration! 🍾🎉 We’re looking forward to another couple of years with Ananya as she takes on the new role of senior grad student @sinaiimmuno.bsky.social 😁
May 19, 2025 at 8:47 PM
Congrats to @ananya-p.bsky.social on her outstanding Master’s defense on #gdTcell migration! 🍾🎉 We’re looking forward to another couple of years with Ananya as she takes on the new role of senior grad student @sinaiimmuno.bsky.social 😁
Reposted by Andrew
#Bluetorial: In our latest paper on #gdTcells and #IBD in #ScienceImmunology we found that γδ IEL number and regulatory function are severely compromised BEFORE ileal inflammation occurs, suggesting that γδ IELs may maintain IEL homeostasis in response to a pro-inflammatory microenvironment. 1/n
two men are riding a bicycle with a basket on it .
ALT: two men are riding a bicycle with a basket on it .
media.tenor.com
March 22, 2025 at 8:05 PM
#Bluetorial: In our latest paper on #gdTcells and #IBD in #ScienceImmunology we found that γδ IEL number and regulatory function are severely compromised BEFORE ileal inflammation occurs, suggesting that γδ IELs may maintain IEL homeostasis in response to a pro-inflammatory microenvironment. 1/n
Reposted by Andrew
If you read our #ScienceImmunology paper and want to know how the #microbiota induces #CD39 to promote a #gdTcell #immunoregulatory phenotype, check out our new #preprint!
Microbiota promote enhanced CD39 expression in γδ intraepithelial lymphocytes through the activation of TCR and IL-15 signaling
Intraepithelial lymphocytes expressing the γδ T cell receptor (γδ IEL) provide continuous surveillance of the intestinal epithelium. We report that mice harboring a microbiota-specific hyperproliferat...
www.biorxiv.org
March 25, 2025 at 8:15 PM
If you read our #ScienceImmunology paper and want to know how the #microbiota induces #CD39 to promote a #gdTcell #immunoregulatory phenotype, check out our new #preprint!
Reposted by Andrew
📣 New preprint drop! In #ScienceImmunology, we found that regulatory #CD39 γδ IELs are reduced in #IBD, now @saraalonsomera.bsky.social shows that gut #microbiota promote enhanced CD39 expression in γδ IELs through #TCR and IL-15 activation. #gdTcells #GIresearch #Gastrosky @sinaiimmuno.bsky.social
Microbiota promote enhanced CD39 expression in γδ intraepithelial lymphocytes through the activation of TCR and IL-15 signaling https://www.biorxiv.org/content/10.1101/2025.03.22.644616v1
March 26, 2025 at 2:26 PM
📣 New preprint drop! In #ScienceImmunology, we found that regulatory #CD39 γδ IELs are reduced in #IBD, now @saraalonsomera.bsky.social shows that gut #microbiota promote enhanced CD39 expression in γδ IELs through #TCR and IL-15 activation. #gdTcells #GIresearch #Gastrosky @sinaiimmuno.bsky.social
Reposted by Andrew
Congrats to co-first authors @weilix27.bsky.social and @nbgolovchenko.bsky.social on their fantastic achievement and hard work getting this project off the ground! Thanks to Irving for all the help in the revision process and the many labmates @andrewfong.bsky.social that contributed. 9/n
a man in a suit and tie is standing next to a woman in a blue tank top and a man in a white shirt .
ALT: a man in a suit and tie is standing next to a woman in a blue tank top and a man in a white shirt .
media.tenor.com
March 22, 2025 at 8:05 PM
Congrats to co-first authors @weilix27.bsky.social and @nbgolovchenko.bsky.social on their fantastic achievement and hard work getting this project off the ground! Thanks to Irving for all the help in the revision process and the many labmates @andrewfong.bsky.social that contributed. 9/n
Reposted by Andrew
@sinaiimmuno.bsky.social just gained a rockstar #PhD student with the acceptance of @ananya-p.bsky.social! Come see why we’re so lucky that Ananya will be joining us for a few more years at the APS Summit. She’ll be presenting two flashtalks (#GIL Trainee Symposium & Forte) on #gdTcell #migration 😍
March 21, 2025 at 10:56 PM
@sinaiimmuno.bsky.social just gained a rockstar #PhD student with the acceptance of @ananya-p.bsky.social! Come see why we’re so lucky that Ananya will be joining us for a few more years at the APS Summit. She’ll be presenting two flashtalks (#GIL Trainee Symposium & Forte) on #gdTcell #migration 😍
Reposted by Andrew
📚NEW #gdTcell PAPER ALERT! Dysregulation of γδ intraepithelial lymphocytes precedes Crohn’s disease–like ileitis | Science Immunology
Bluetorial coming soon!!! #gastrosky #GIsky #IBDsky @nbgolovchenko.bsky.social @squeakyanimal.bsky.social @andrewfong.bsky.social
Bluetorial coming soon!!! #gastrosky #GIsky #IBDsky @nbgolovchenko.bsky.social @squeakyanimal.bsky.social @andrewfong.bsky.social
Dysregulation of γδ intraepithelial lymphocytes precedes Crohn’s disease–like ileitis
Multiple layers of γδ IEL dysregulation and loss of their immunosuppressive capacity occur before the onset of chronic ileitis.
www.science.org
March 21, 2025 at 6:14 PM
📚NEW #gdTcell PAPER ALERT! Dysregulation of γδ intraepithelial lymphocytes precedes Crohn’s disease–like ileitis | Science Immunology
Bluetorial coming soon!!! #gastrosky #GIsky #IBDsky @nbgolovchenko.bsky.social @squeakyanimal.bsky.social @andrewfong.bsky.social
Bluetorial coming soon!!! #gastrosky #GIsky #IBDsky @nbgolovchenko.bsky.social @squeakyanimal.bsky.social @andrewfong.bsky.social
Reposted by Andrew
Congratulations to Dr. Sara Alonso on a spectacular defense! 👏 🍾 Sara is a powerhouse of #gdTcell #immunometabolism data in the lab. We can’t wait to share the #preprint of her thesis work on #gdTcells and #microbiota with you later this week. @sinaiimmuno.bsky.social
March 18, 2025 at 10:06 PM
Congratulations to Dr. Sara Alonso on a spectacular defense! 👏 🍾 Sara is a powerhouse of #gdTcell #immunometabolism data in the lab. We can’t wait to share the #preprint of her thesis work on #gdTcells and #microbiota with you later this week. @sinaiimmuno.bsky.social
Reminder to floss on #FluorescenceFriday just like this gamma delta IEL (pink)!
March 14, 2025 at 5:24 PM
Reminder to floss on #FluorescenceFriday just like this gamma delta IEL (pink)!