Andrew Hires
@andrewhires.bsky.social
850 followers 230 following 97 posts
Job: Neurobiology @ USC Likes: Bikes, crypto, techno What’s next?
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andrewhires.bsky.social
What’s the next number in this sequence (just handed to me by my 6yo son).

Simple but stumped me and GPT.
andrewhires.bsky.social
Today, I gave an informal seminar to students and faculty on the accelerating impact new AI models like o3 will have on research and how to navigate those changes.

Check it out👇

Resistance is Futile: AGI-Augmented Research and the New Scientific Method youtu.be/x6gv68fHw7Q?... via @YouTube
Resistance is Futile: AGI-Augmented Research and the New Scientific Method
YouTube video by Samuel Hires
youtu.be
andrewhires.bsky.social
Unfortunately all my submissions are outstanding, so I don’t have the appropriate test set. 😅

I expect you could easily put the finger on the scale to be more aggressive in critiques with an o3-level model though. For future explorations…
andrewhires.bsky.social
It's been 3.5 months since this experiment on scientific reasoning. The improvements in SOTA models since are remarkable.

Here's OpenAI's o3 model's first attempt at reviewing my 2017 R01-A1 submission. Would you do a better job?
andrewhires.bsky.social
Come on, you didn’t have just a twinge of curiosity about the experience of being assimilating into a galactically powerful collective super-intelligence? A bit of doubt that we, the humans, were the baddies?
andrewhires.bsky.social
The latest reasoning models (o3, Gemini 2.5 Pro), hold more knowledge, reason better, and communicate more clearly than you or me.

If you aren’t trying to integrate them to all elements of the research workflow, you are doing yourself and your trainees a disservice. Resistance is futile.
a man with a robotic helmet on his head and the words `` resistance is futile '' written on the bottom .
ALT: a man with a robotic helmet on his head and the words `` resistance is futile '' written on the bottom .
media.tenor.com
andrewhires.bsky.social
If you don't realize that AGI is already here, you must be too lazy or incurious to try o3.
andrewhires.bsky.social
Noooooo Spotify account needed. Not sure they have my bangers.
andrewhires.bsky.social
I have some new heaters.
andrewhires.bsky.social
Testing out DeepSeek-R1's ability to do "science" in one-shot.

I asked it to critique my 2017 R01 proposal (Impact 26, 10%, funded by NINDS. I wrote the proposal, have rights to share it.

It's first-shot response is indistinguishable from a median quality reviewer's.

What do we do now?
andrewhires.bsky.social
If anyone wants to follow along, I have a bunch of media posts on X. Sorry no time to duplicate.

Pacific Palisades is mostly destroyed. Half my friends have lost their homes. Mine not gone yet but not looking good.
andrewhires.bsky.social
How my day is going #PalisadesFire
andrewhires.bsky.social
Trying to get my ring video
andrewhires.bsky.social
Good morning 2025!

Thank you LAFD!
andrewhires.bsky.social
This is a thread, brother. 😁
andrewhires.bsky.social
The lineup.

Toasty Bollinger
Trusty, well priced Guigal CduR
Drouhin Pinot (wow!)
andrewhires.bsky.social
Bringing my cooking talents to Bluesky