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Reposted by Anita Luthi

fbm-unil.bsky.social @fbm-unil.bsky.social · Aug 4

Congratulations to @anitaluthi.bsky.social and @manumameli.bsky.social 🎓👏

www.linkedin.com/posts/depart...

Two new full professorships strengthen neuroscience at UNIL! | Department of Fundamental Neurosciences - DNF, University of Lausanne

Two new full professorships strengthen neuroscience at UNIL! We are delighted to announce that two leading researchers from the Department of Fundamental Neurosciences (DNF) of the FBM UNIL - Faculté...

www.linkedin.com

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Anita Luthi @anitaluthi.bsky.social · Jul 20

Congrats Laurent, so well-deserved! Thrilled to be working with you in the near future!

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Thomas Andrillon @thomasandrillon.bsky.social · May 28

Our conclusion: there is a signature of IH in sleep but the causes might be found in wake!

Thanks @institutducerveau.bsky.social, @inserm.fr, @aphp.bsky.social and @erc.europa.eu for supporting this work!

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Thomas Andrillon @thomasandrillon.bsky.social · May 28

And here is the preprint:
www.biorxiv.org/content/10.1...

EEG Signature of Idiopathic Hypersomnia: Insights from Sleep Microarchitecture and Hypnodensity Metrics

Background and Objectives: Patients with idiopathic hypersomnia with long sleep time (IH) report daytime hypersomnolence despite prolonged sleep time and normal sleep macrostructure. As they often hav...

www.biorxiv.org

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Sleep Research Lab at University of Lausanne @labluthi.bsky.social · May 18

@LabLuthi congratulates Dr. Georgios Foustoukos for the Best Publication Award 2025 from the #SSSSC, the #Swiss Society for #Sleep Research, Sleep Medicine and #Chronobiology. A nice recognition of your outstanding experimental and analytical skills!👏 @fbm-unil.bsky.social @natneuro.nature.com

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Anita Luthi @anitaluthi.bsky.social · Mar 18

👉👉new paper alert from @labluthi.bsky.social - so proud for talented and determined Dr.Najma Cherrad who opened the lab‘s access to brain-body communication! #sleep #locuscoeruleus #parasympathetic @fbm-unil.bsky.social

bioRxiv Neuroscience @biorxiv-neursci.bsky.social · Mar 16

Vagal afferent activation induces a NREM-sleep-like state with brain-body cooling, but locus coeruleus activation https://www.biorxiv.org/content/10.1101/2025.03.14.643122v1

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Anita Luthi @anitaluthi.bsky.social · Mar 18

👉👉new paper alert from @labluthi.bsky.social - so proud for talented and determined Dr.Najma Cherrad who opened the lab‘s access to brain-body communication! #sleep #locuscoeruleus #parasympathetic @fbm-unil.bsky.social

bioRxiv Neuroscience @biorxiv-neursci.bsky.social · Mar 16

Vagal afferent activation induces a NREM-sleep-like state with brain-body cooling, but locus coeruleus activation https://www.biorxiv.org/content/10.1101/2025.03.14.643122v1

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Laurent Sheybani @laurentsheybani.bsky.social · Mar 4

Can you learn while sleeping? Does sleep help you solve problems? What is the effect of sleep on brain metabolism?
--> my last editorial @braincomms.bsky.social
doi.org/10.1093/brai...

Sleep is not a homogenous state - just like wake. Asking the role of sleep is as fair as asking the role of wake!

pendingpublications

Pending Publication

doi.org

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Neuron @cp-neuron.bsky.social · Feb 19

Here's our latest issue: www.cell.com/neuron/current

The cover is for a Perspective piece by Lüthi & Nedergaard who discuss microarousals, and propose an inverted U-shaped relationship to reconcile their essential and disruptive roles: www.cell.com/neuron/fullt...

Cover by Nadia Alzoubi

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Anita Luthi @anitaluthi.bsky.social · Feb 4

What a pleasure to be interviewed by science writer @davidarobson.bsky.social, what an even greater pleasure to read his visionary narrative in BBC future!

David Robson @davidarobson.bsky.social · Feb 4

My latest for the BBC explores how the brain's "little blue dot" regulates our sleep, which is inspiring new ways to treat insomnia.

I was especially interested to know that yoga/slow breathing in the evening may reduce micro-awakenings at night, which I now use myself

www.bbc.com/future/artic...

How the brain's little blue dot regulates your sleep

The locus coeruleus is emerging as a major new area of research interest, with many important functions such as regulating our attention and sleep.

www.bbc.com

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Anita Luthi @anitaluthi.bsky.social · Jan 11

Agree! Watch out for a first Perspective on this proposed by Maiken and me, coming out on Monday, Jan 13, in Neuron.

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Laurent Sheybani @laurentsheybani.bsky.social · Jan 9

@anitaluthi.bsky.social

Pierre Champetier @champetier-pierre.bsky.social · Jan 9

Research on infraslow oscillations during NREM sleep is definitely a hot topic ! 🔥 New paper making the link between norepinephrine oscillations and glymphatic clearance 🧠🚿
@cellcellpress.bsky.social @nataliehauglund.bsky.social
www.cell.com/cell/abstrac...

Norepinephrine-mediated slow vasomotion drives glymphatic clearance during sleep

Norepinephrine oscillations during NREM sleep drive synchronized changes in cerebral blood volume and cerebrospinal fluid, promoting glymphatic clearance. Optogenetic and pharmacological manipulations confirm that vasomotion, regulated by norepinephrine, acts as a pump for brain fluid transport.

www.cell.com

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Anita Luthi @anitaluthi.bsky.social · Jan 8

Important study on the timing pattern of #sleep #spindles in human EEG and of fingerprints that characterize individuals across age and demographic factors 👏👏

Laurent Sheybani @laurentsheybani.bsky.social · Jan 8

Timing of spindles are governed by individual rules --> doi.org/10.1073/pnas... @anitaluthi.bsky.social @labnir.bsky.social @vyazovskiy.bsky.social

PNAS

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

doi.org

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Anita Luthi @anitaluthi.bsky.social · Dec 14

Merci Thoma!

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Thomas Andrillon @thomasandrillon.bsky.social · Nov 27

Amazing work from the team of Anita Lüthi!

Infraslow noradrenergic locus coeruleus activity fluctuations are gatekeepers of the NREM–REM sleep cycle
www.nature.com/articles/s41...
💤🧪🧠

Infraslow noradrenergic locus coeruleus activity fluctuations are gatekeepers of the NREM–REM sleep cycle - Nature Neuroscience

Lüthi and colleagues show that activity of the locus coeruleus (LC) is crucial for the cyclic alternation between non-rapid-eye-movement and rapid-eye-movement sleep. Stressful experiences during waki...

www.nature.com

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Klara Soukup @klarasoukup.bsky.social · Nov 29

Alors c’est parti: 1er post, en français:

Récente découverte @unil.bsky.social: une toute petite région du cerveau qui s’appelle « locus coeruleus » détermine si nos nuits sont bien rhythmées entre les phases du #sommeil paradoxal et profond.

www.unil.ch/news/1723726...

Une nouvelle horloge pour structurer le sommeil

Des scientifiques au sein de la FBM-UNIL ont identifié un nouveau rôle du locus cœruleus dans le sommeil et ses troubles. Cette région cérébrale permet la transition entre les états du sommeil et le m...

www.unil.ch

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Johannes Bohacek @bohaceklab.bsky.social · Nov 28

🔵 blue spot alert: Anita Luethi's team reports a dual role of #locuscoeruleus in #sleep in Nature Neuroscience @natureportfolio.bsky.social

1) high LC activity facilitates cortical microarousals
2) low LC activity is required for NREMS-to-REMS transitions

doi.org/10.1038/s415...

Infraslow noradrenergic locus coeruleus activity fluctuations are gatekeepers of the NREM–REM sleep cycle - Nature Neuroscience

Lüthi and colleagues show that activity of the locus coeruleus (LC) is crucial for the cyclic alternation between non-rapid-eye-movement and rapid-eye-movement sleep. Stressful experiences during waki...

doi.org

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