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Anne Loft

@anneloftsdu.bsky.social

48 followers 90 following 20 posts

Principal Investigator at Functional Genomics and Metabolism Unit at SDU (Odense). Dissecting adipose tissue (dys)function through single-cell genomics to uncover cellular mechanisms underlying metabolic health and disease.

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Anne Loft @anneloftsdu.bsky.social · Mar 6

📣 Check out our recent preprint on bioRxiv on cellular changes in adipose tissue in response to different weight loss modalities 📣

Jesper Madsen @jespergrud.bsky.social · Feb 1

Preprint alert! We used snRNA-seq on adipose tissue from a longitudinal cohort of people undergoing surgury-induced weight loss. True ATLAS team effort

We found dramatic changes in immune and progenitor compartments. Give it a read and let us know what you think.

www.biorxiv.org/content/10.1...

Single cell-resolved transcriptional dynamics of human subcutaneous adipose tissue during lifestyle- and bariatric surgery-induced weight loss

During sustained weight gain, human white adipose tissue undergoes dramatic remodeling that may compromise adipose tissue function and lead to obesity comorbidities such as cardiometabolic disease. Th...

www.biorxiv.org

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Anne Loft @anneloftsdu.bsky.social · Jul 11

📢 PhD Position in Functional Genomics 🧬

Join my international team at the Functional Genomics & Metabolism Research Unit at the University of Southern Denmark 🇩🇰 to explore cardiometabolic disease using single-cell sequencing-based technologies 💥

👉 Apply here: lnkd.in/duPR-B6k

This link will take you to a page that’s not on LinkedIn

lnkd.in

Anne Loft @anneloftsdu.bsky.social · May 14

Check out our new roadmap for single cell analyses of adipose tissue at @natmetabolism.nature.com 🧐 Thrilled to share our work put together by great colleagues from Adipose Bionetwork in @humancellatlas.org 🤩 Huge thanks to my fellow co-coordinators @smandrup.bsky.social Evan Rosen and Margo Emont

Nature Metabolism @natmetabolism.nature.com · May 13

Towards a consensus atlas of human and mouse adipose tissue at single-cell resolution

Nature Metabolism, Published online: 13 May 2025; doi:10.1038/s42255-025-01296-9In this Review, the authors present a roadmap towards achieving consensus on development, analysis and interpretation of single-cell transcriptomics data in adipose tissue, including discussion of roadblocks, best practices and ideal cell-type markers for annotation of adipose tissue cell types in mice and humans.

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Anne Loft @anneloftsdu.bsky.social · Mar 6

📣 Check out our recent preprint on bioRxiv on cellular changes in adipose tissue in response to different weight loss modalities 📣

Jesper Madsen @jespergrud.bsky.social · Feb 1

Single cell-resolved transcriptional dynamics of human subcutaneous adipose tissue during lifestyle- and bariatric surgery-induced weight loss

www.biorxiv.org

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Anne Loft @anneloftsdu.bsky.social · Mar 6

Enjoying all aspects of #MetabolismInAction2022: interesting research 🤓 great discussions with dedicated colleagues 🤩 a fantastic venue 💥 and the tasty (H)ugo Spritz served by @MelinaClaussnit at the PI pub🥂😅

@novonordiskfond @ScienceCluster @ATLAS_SDU @bmbSDU

Anne Loft @anneloftsdu.bsky.social · Mar 6

Enjoying a fabelous BBQ get-together in the fantastic danish summer 🤩 @ATLAS_SDU @bmbSDU

Anne Loft @anneloftsdu.bsky.social · Mar 6

Really honored to receive the 'Deutsche Leberstiftung Preis 2022' together with @Ana_Jim_Alf and Stephan Herzig for our @Cell_Metabolism work on hepatocyte fate in NASH. Thanks to everyone involved @helmholtz_diabc @ATLAS_SDU @NATsdu

Anne Loft @anneloftsdu.bsky.social · Mar 6

Thanks to @sciencenewsdk for highlighting our research on how the immune system impacts on fasting metabolism 🤓 #fasting #immunesystem #health #metabolism

@CarattiGX @FiskerSchmidt @JanTuckermann @helmholtz_diabc @ATLAS_SDU @NATsdu

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Anne Loft @anneloftsdu.bsky.social · Mar 6

Come join our fabulous research unit in Odense 🤩 this inventive guy has my strongest personal recommendations 😄

x.com/FiskerSchmidt/…

Anne Loft @anneloftsdu.bsky.social · Mar 6

If you are interested in understanding how transcription factors and cofactors work 🤓, this is a great opportunity to get supervision from a brilliant and super nice guy 🤩

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Anne Loft @anneloftsdu.bsky.social · Mar 6

Join our research unit and get the chance to be supervised by these guaranteed cool and nice PI's 🤩

x.com/FiskerSchmidt/…

Anne Loft @anneloftsdu.bsky.social · Mar 6

Interested in dissecting TF networks of brown adipocytes? Some tips to how this can be done (including new data🧐) with @maja_worm @jespergrud @susmandrup @ATLAS_SDU. Thanks for being a part of this great method collection @WolfrumLab @guertin_lab

bit.ly/3HdIeBO

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Anne Loft @anneloftsdu.bsky.social · Mar 6

Spread the word📣 Our work in @Cell_Metabolism showing how GR in macrophages coordinates fasting ketogenesis via hepatocyte GR is now out. Thanks to everyone involved 🥳 @FiskerSchmidt @helmholtz_diabc @JanTuckermann @ATLAS_SDU @bmbSDU @novonordiskfond

x.com/FiskerSchmidt/…

Anne Loft @anneloftsdu.bsky.social · Mar 6

Science made easy 😉 Go to @JRNLclub and get our recent @Cell_Metabolism paper on hepatocyte crosstalk in NASH and liver fibrosis served🥳 @helmholtz_diabc @GenomicsUnit @ATLAS_SDU @NATsdu

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Anne Loft @anneloftsdu.bsky.social · Mar 6

Our work on hepatocyte fate in NASH in @Cell_Metabolism was highligted as one of the important omics-directed discoveries in liver fibrosis research in 2021 by @NatRevGastroHep 💪🤩 Thanks once again @Ana_Jim_Alf @helmholtz_diabc @ATLAS_SDU @novonordiskfond

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Anne Loft @anneloftsdu.bsky.social · Mar 6

Finally back together at the #bringmebackfestival with favorite unit members from the @GenomicsUnit. Even got a chance to reuse my Octoberfest costume 🍻 Thanks for making this possible @bmbSDU @NATsdu 🤩🙌

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Anne Loft @anneloftsdu.bsky.social · Mar 6

Proud to announce our new paper on hepatocyte 'fate' in #NASH and liver fibrosis in @Cell_Metabolism. Special thanks to @Ana_Jim_Alf, Stephan Herzig and other great colleagues at @helmholtz_diabc @bmbSDU @ATLAS_SDU 💪. Now in perfect mood for #ENGDEN 🇩🇰⚽️🏆🍾

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Anne Loft @anneloftsdu.bsky.social · Mar 6

Enjoying life at Svanninge Mountains with great colleagues #retreat #summer #science @susmandrup group @GenomicsUnit @bmbSDU

Anne Loft @anneloftsdu.bsky.social · Mar 6

Favourite postdoc teammates @BManiyadath and @AjeethaJo rocking our football Boot Camp. Thanks to all @GenomicsUnit members for arranging a much-awaited and memorable get together event 🥳

x.com/susmandrup/sta…

Anne Loft @anneloftsdu.bsky.social · Mar 6

Fantastic to be "back" with old friends and colleagues at the @helmholtz_diabc and great fun to be a part of the Flash Talk competition. Thanks for an amazing conference!

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