Lightnews — Scholar-powered news

Annina Schmid @anninaschmid.bsky.social · 9d

We are beyond excited about this new MSc in Pain Neurosciences programme!! 🧑‍🎓👩‍🎓 come join our buzzing Oxford pain community!!

Nuffield Department of Clinical Neurosciences @ndcnoxford.bsky.social · 9d

September is #PainAwarenessMonth, and we are excited to be launching our brand-new MSc in Pain Neurosciences. Could you help shape the future of #pain research? Opening soon for 2026 admissions 👀

Learn more 👇
bit.ly/OxMScPain

New MSc in Pain Neurosciences. Ready to shape the future of pain research? Applications open soon for 2026 admission.

3

Annina Schmid @anninaschmid.bsky.social · Mar 31

Thanks for having us Mark, always nice to share science! Have a look at this if you are interested in whiplash associated disorder and our recent evidence for nerve pathology and neuropathic pain in some: youtu.be/yip3I689cwU

Whiplash Isn’t Just Neck Pain: What Clinicians Are Missing

YouTube video by Modern Pain Podcast

youtu.be

1 1

Annina Schmid @anninaschmid.bsky.social · Mar 7

Thanks Ted, I will forward this to my collaborators🥳

1

Annina Schmid @anninaschmid.bsky.social · Mar 6

Cool that these are helpful to you, I will watch out for your publications then!!

1 1

Reposted by Annina Schmid

Kate Dunn @katemdunn.bsky.social · Mar 5

We have an opportunity for a funded PhD studentship on 'Illness perceptions and outcomes in people living with gout'. See: www.keele.ac.uk/study/postgr... #KeeleMSK

Illness perceptions and outcomes in people living with gout

www.keele.ac.uk

2 3

Annina Schmid @anninaschmid.bsky.social · Mar 5

and most importantly, a massive thank you to all participants who made this study possible. thank you for your generous time commitment and patience!

@ndcnoxford.bsky.social
@ox.ac.uk

3

Annina Schmid @anninaschmid.bsky.social · Mar 5

A massive thank you again to all co-authors, particularly
Joel Fundaun, Colette Ridehalgh and Andrew Dilley.
Particular thanks to our generous funders
@versusarthritis.bsky.social @medresfdn.bsky.social

1 4

Annina Schmid @anninaschmid.bsky.social · Mar 5

Overall, our results present a complex phenotypic profile for people with WADII and provide evidence suggestive of peripheral neuroinflammation in a subgroup of individuals.

1 2

Annina Schmid @anninaschmid.bsky.social · Mar 5

Several serum pro-inflammatory cytokines were raised in people with WADII. So inflammation can be detected systemically. x.com/AnninaBSchmi...

1 3

Annina Schmid @anninaschmid.bsky.social · Mar 5

Magnetic resonance imaging T2 signal ratio was increased in the C5 root of the brachial plexus and the C5-C8 dorsal root ganglia in WADII participants compared with healthy controls. We did not find changes in the distal median nerve trunk.

1 1

Annina Schmid @anninaschmid.bsky.social · Mar 5

In the other publication published in
@painthejournal.bsky.social, we focussed on the presence of neuroinflammation in these patients using MRI, serum cytokine evaluation as well as other measures.
journals.lww.com/pain/fulltex...

Evidence for peripheral neuroinflammation after acute... : PAIN

a subgroup with underlying nerve involvement in WADII, such as peripheral neuroinflammation. This study aimed to investigate the presence of neuroinflammation in acute WADII using T2-weighted magnetic...

journals.lww.com

1 2 4

Annina Schmid @anninaschmid.bsky.social · Mar 5

Multivariable linear regression suggested low-cost bedside tests for hypoaesthesia at the index finger were prognostic for whiplash-related upper quadrant pain 6-months post-injury, however this association was weak.

1 1

Annina Schmid @anninaschmid.bsky.social · Mar 5

We also took skin biopsies. Intraepidermal nerve fibre densities at the index finger were not significantly different between groups. However, dermal myelinated nerve bundles at the index finger were reduced 6-months post-injury in participants with WADII compared to controls.

1 1

Annina Schmid @anninaschmid.bsky.social · Mar 5

Intriguingly, these functional changes were accompanied by elevated serum neurofilament light chain levels (a marker for axonal damage) acutely after whiplash. This normalised 6 months later. This suggests there is actual structural damage to axons in some people with WADII.

1 1

Annina Schmid @anninaschmid.bsky.social · Mar 5

QST demonstrated significantly reduced thermal and mechanical detection thresholds in acute WADII compared to controls, some of which persisted at 6 months.

1 1

Annina Schmid @anninaschmid.bsky.social · Mar 5

Within 4 weeks of injury, 65% of people with WADII had neuropathic pain which persisted in 32% 6-months post-injury.

1 1 2

Annina Schmid @anninaschmid.bsky.social · Mar 5

In this @brain1878.bsky.social publication, we demonstrate that people with WADII (traditionally not considered to involve nerve injury) have signs of functional and structural nerve pathology.
academic.oup.com/brain/advanc...

Validate User

academic.oup.com

1 1 3

Annina Schmid @anninaschmid.bsky.social · Mar 5

What an exciting week: two papers published in
@brain1878.bsky.social and @painthejournal.bsky.social on the findings from our whiplash cohort. Massive thank you Joel Fundaun, Colette Ridehalgh, Andrew Dilley and other co-authors who were instrumental in making this happen. Short summary below.

2 5 15

Annina Schmid @anninaschmid.bsky.social · Feb 14

Do you have a basic science background and are interested in doing a PhD at Oxford University? Fully funded UK studentship available for 2025 intake to study the role of B-cells in human neuropathic pain

To apply please see here:
www.ndcn.ox.ac.uk/study-with-u...

a man in a suit and tie is holding a pen and hammer .

ALT: a man in a suit and tie is holding a pen and hammer .

media.tenor.com

9 10

Annina Schmid @anninaschmid.bsky.social · Feb 8

Haha, welcome online Falko! Great to meet you!!!

1 1

Annina Schmid @anninaschmid.bsky.social · Dec 11

Agree, super cool!!!

1

Annina Schmid @anninaschmid.bsky.social · Dec 4

Thank you!!!

Annina Schmid @anninaschmid.bsky.social · Dec 4

Wonderful, thank you!!! Still finding my way here 😉

1