Lightnews — Scholar-powered news

Reposted by Antimicrobial Resistance, Omics & Microbiota (AROM) @ NTU

Jack C. Leo @jackcleo.bsky.social · 22d

A new preprint from my group, representing the PhD work of Rachael Duodu. Thanks to @bugsinyourguts.bsky.social for transcriptomics analysis!

bioRxiv Microbiology @biorxiv-microbiol.bsky.social · 23d

The Omp85 family protein, TamA, exhibits characteristics 1 of a suitable drug target against Pseudomonas aeruginosa https://www.biorxiv.org/content/10.1101/2025.09.16.676292v1

2 1

Antimicrobial Resistance, Omics & Microbiota (AROM) @ NTU @arom-ntu.bsky.social · 22d

Congratulations to Rachael Duodu on the first preprint from her PhD work, under the supervision of @jackcleo.bsky.social!

bioRxiv Microbiology @biorxiv-microbiol.bsky.social · 23d

The Omp85 family protein, TamA, exhibits characteristics 1 of a suitable drug target against Pseudomonas aeruginosa https://www.biorxiv.org/content/10.1101/2025.09.16.676292v1

1

Reposted by Antimicrobial Resistance, Omics & Microbiota (AROM) @ NTU

Sandra Díaz Sánchez @sdiazsanchez.bsky.social · 26d

📢 We offer a fully funded 4-year #PhD position to work on tick #microbiota 🦠 dynamics using #genomics 🧬 at @irec-csic-uclm.bsky.social, supervised by @sdiazsanchez.bsky.social. For requisites and contact info, please check 👇

www.irec.es/noticias/pro...

2 13 10

Reposted by Antimicrobial Resistance, Omics & Microbiota (AROM) @ NTU

Microbiota and Host @microbiotaandhost.bsky.social · Jun 4

This new review by Anne L McCartney and Lesley Hoyles examines the often overlooked role of Klebsiella bioactives in host-microbiota dynamics.

🔗 Access the full article here: doi.org/10.1530/MAH-24-0011

1 4 2

Reposted by Antimicrobial Resistance, Omics & Microbiota (AROM) @ NTU

Gareth McVicker @mcvickermicro.bsky.social · Jun 16

On our way to @mgeworkshop.bsky.social for @lotox.bsky.social to present later. Looking forward to some amazing talks! @arom-ntu.bsky.social #mgeworkshop

1

Reposted by Antimicrobial Resistance, Omics & Microbiota (AROM) @ NTU

aurelianachilengue.bsky.social @aurelianachilengue.bsky.social · Jun 11

I am Honoured to have received the 2nd Prize at NTU's ⭐️ STAR (Science & Tech Annual Research) Conference!
Special thanks to my supervisors @conmeehan.bsky.social @blackpassiflora.bsky.social and collaborators @danwhiley.bsky.social @Kate Cox for the incredible support.
@arom-ntu.bsky.social

4 7

Reposted by Antimicrobial Resistance, Omics & Microbiota (AROM) @ NTU

Professor Lesley Hoyles @bugsinyourguts.bsky.social · May 13

Great to see the typeset version of this invited review out.

Covers pretty much everything we know about metabolites/peptides produced by Klebsiella spp. and how they interact with the host. #microsky #microbiomesky @microbiotaandhost.bsky.social

doi.org/10.1530/MAH-...

Host interactions of bioactive molecules produced by Klebsiella spp

Abstract Klebsiella spp. are early colonisers and commensals of human skin, oral, nasal, throat and gut microbiotas, but are also opportunistic pathogens. Much of our information on these bacteria is ...

doi.org

4 5

Antimicrobial Resistance, Omics & Microbiota (AROM) @ NTU @arom-ntu.bsky.social · May 13

New preprint out from Jack C. Leo and colleagues! #microsky

Formation of the β-sheet at the extracellular opening of the intimin β-barrel domain is necessary for stability and efficient passenger secretion

Attaching and effacing pathogens, such as enteropathogenic and enterohaemorrhagic E. coli, rely on an adhesin, intimin, for attachment to enterocytes and downstream effects leading to actin pedestal f...

www.biorxiv.org

1

Antimicrobial Resistance, Omics & Microbiota (AROM) @ NTU @arom-ntu.bsky.social · May 13

Congratulations to @conmeehan.bsky.social and colleagues on the publication of their new manuscript. #microsky

Pitfalls of bacterial pan-genome analysis approaches: a case study of M. tuberculosis and two less clonal bacterial species

Abstract . Pan-genome analysis is a fundamental tool for studying bacterial genome evolution; however, the variety of methods used to define and measure th

academic.oup.com

2 3

Reposted by Antimicrobial Resistance, Omics & Microbiota (AROM) @ NTU

David Negus @davidnegus.bsky.social · Apr 25

🚨New publication🚨
We show that K. Pneumoniae bacteriophages can be incorporated into alginate to create an antibiofilm matrix effective against clinical K. pneumoniae strains
academic.oup.com/jambio/artic...

Bacteriophage-embedded and coated alginate layers inhibit biofilm formation by clinical strains of Klebsiella pneumoniae

AbstractAims. This study aimed to determine the antibiofilm properties of Klebsiella pneumoniae phages previously isolated from Thai hospital sewage water.

academic.oup.com

1 7 15

Reposted by Antimicrobial Resistance, Omics & Microbiota (AROM) @ NTU

Dan Whiley @danwhiley.bsky.social · Mar 31

First from the @arom-ntu.bsky.social group is @jodywinter.bsky.social who was awarded the 2024 Microbiology in Society Award. Jody is talking about education outreach and research as an invited talk.

1 2 4

Antimicrobial Resistance, Omics & Microbiota (AROM) @ NTU @arom-ntu.bsky.social · Apr 2

Congratulations to Caitlin Wildsmith on the second paper from her PhD with @davidnegus.bsky.social! #microsky

Genomic and phenotypic characterization of staphylococci isolated from the skin of non-human primates

The growth of wildlife tourism coupled with continued deforestation has resulted in increased contact between non-human primates (NHPs) and humans. Such events may promote the transmission of potentia...

www.microbiologyresearch.org

2 6

Reposted by Antimicrobial Resistance, Omics & Microbiota (AROM) @ NTU

Gareth McVicker @mcvickermicro.bsky.social · Mar 27

Incredibly happy to see this paper come out! And first research paper for @lotox.bsky.social! Thanks also to all the collabs at @arom-ntu.bsky.social

www.microbiologyresearch.org/content/jour...

Genetic and phenotypic analysis of the virulence plasmid of a non-Shigatoxigenic enteroaggregative Escherichia coli O104:H4 outbreak strain

Enteroaggregative Escherichia coli O104:H4 is best known for causing a worldwide outbreak in 2011 due to the acquisition of a Shiga-like toxin alongside traditional enteroaggregative virulence traits;...

www.microbiologyresearch.org

4 7

Antimicrobial Resistance, Omics & Microbiota (AROM) @ NTU @arom-ntu.bsky.social · Mar 28

Congratulations to PhD students Rachel and Lottie, and MRes student Martyna on their publication with @mcvickermicro.bsky.social! #microsky

www.microbiologyresearch.org/content/jour...

Genetic and phenotypic analysis of the virulence plasmid of a non-Shigatoxigenic enteroaggregative Escherichia coli O104:H4 outbreak strain

Enteroaggregative Escherichia coli O104:H4 is best known for causing a worldwide outbreak in 2011 due to the acquisition of a Shiga-like toxin alongside traditional enteroaggregative virulence traits;...

www.microbiologyresearch.org

2 5

Antimicrobial Resistance, Omics & Microbiota (AROM) @ NTU @arom-ntu.bsky.social · Mar 13

Congratulations to @conmeehan.bsky.social and colleagues on their new publication!

Conor (Conchúr) Meehan @conmeehan.bsky.social · Mar 13

We published a cool new paper showing that some M tuberculosis lineages (mainly L1 and L6) seem less transmissible but that's mainly because they have longer initial non-infectious 'latent' periods.

www.sciencedirect.com/science/arti...

Onset of infectiousness explains differences in transmissibility across Mycobacterium tuberculosis lineages

Mycobacterium tuberculosis complex (MTBC) lineages show substantial variability in virulence, but the epidemiological consequences of this variability…

www.sciencedirect.com

1

Antimicrobial Resistance, Omics & Microbiota (AROM) @ NTU @arom-ntu.bsky.social · Mar 12

New paper from @jodywinter.bsky.social's team on how menadione affects transcriptional responses of Helicobacter pylori. Well done to PhD students Stephen and Rebecca! #microsky #Helicobacter

www.microbiologyresearch.org/content/jour...

Menadione reduces the expression of virulence- and colonization-associated genes in Helicobacter pylori

Novel treatment options are needed for the gastric pathogen Helicobacter pylori due to its increasing antibiotic resistance. The vitamin K analogue menadione has been extensively studied due to intere...

www.microbiologyresearch.org

4

Reposted by Antimicrobial Resistance, Omics & Microbiota (AROM) @ NTU

Alasdair Hubbard @dralhubb.bsky.social · Jan 23

We're running our introductory/launch event for LEAP tonight, unfortunately I can't attend as I'm full of a cold (not great look to start a super spreader event). Though LEAP we hope to bring in more public participation into our research, to find out more and keep up to date follow our BlueSky...

Listen, Engage and Analyse with the Public (LEAP) @leapntu.bsky.social · Jan 23

Tonight is our launch event for LEAP! We're going to be introducing the different topics and events and introduce everyone to the initiative!! Wish us luck, we will update how it goes...

#ScienceSky

3 2

Antimicrobial Resistance, Omics & Microbiota (AROM) @ NTU @arom-ntu.bsky.social · Jan 15

Deadline to apply for this PhD is 14 February.

Antimicrobial Resistance, Omics & Microbiota (AROM) @ NTU @arom-ntu.bsky.social · Nov 20

PhD studentship available with @dralhubb.bsky.social.

Health inequalities which impact the treatment of urinary tract infections www.ntu.ac.uk/study-and-co...

Health inequalities which impact the treatment of urinary tract infections

Find out about this studentship opportunity on Health inequalities which impact the treatment of urinary tract infections.

www.ntu.ac.uk

2

Antimicrobial Resistance, Omics & Microbiota (AROM) @ NTU @arom-ntu.bsky.social · Jan 15

Deadline to apply for this PhD is 14 February.

Antimicrobial Resistance, Omics & Microbiota (AROM) @ NTU @arom-ntu.bsky.social · Nov 20

PhD studentship available with Dr Jonathan Thomas.

Use of Short Interfering RNA to Reduce Antimicrobial Resistance in Bacterial Clinical and Veterinary Pathogens www.ntu.ac.uk/study-and-co...

Use of Short Interfering RNA to Reduce Antimicrobial Resistance in Bacterial Clinical and Veterinary Pathogens

Find out about this studentship opportunity on the use of Short Interfering RNA to Reduce Antimicrobial Resistance in Bacterial Clinical and Veterinary Pathogens.

www.ntu.ac.uk

2

Antimicrobial Resistance, Omics & Microbiota (AROM) @ NTU @arom-ntu.bsky.social · Jan 15

Deadline to apply for this PhD is 14 February.

Antimicrobial Resistance, Omics & Microbiota (AROM) @ NTU @arom-ntu.bsky.social · Nov 20

PhD studentship available with @jodywinter.bsky.social.

One Health drivers of antibiotic resistant bacterial infections in rural Ugandan communities www.ntu.ac.uk/study-and-co...

One Health drivers of antibiotic resistant bacterial infections in rural Ugandan communities

Find out more about this PhD opportunity on the spread of resistant bacteria in rural communities in Uganda.

www.ntu.ac.uk

2

Antimicrobial Resistance, Omics & Microbiota (AROM) @ NTU @arom-ntu.bsky.social · Jan 8

New year, new publication! From @conmeehan.bsky.social and colleagues @tlillebaek.bsky.social ek.bsky.social and @micronorman.bsky.social describing four new species of Mycobacterium.

Four novel nontuberculous mycobacteria species: Mycobacterium wendilense sp. nov., Mycobacterium burgundiense sp. nov., Mycobacterium kokjensenii sp. nov. and Mycobacterium holstebronense sp. nov. rev...

Four novel nontuberculous mycobacteria were discovered from a historical strain collection at the International Reference Laboratory of Mycobacteriology at Statens Serum Institut in Copenhagen, Denmar...

www.microbiologyresearch.org

2 4

Antimicrobial Resistance, Omics & Microbiota (AROM) @ NTU @arom-ntu.bsky.social · Dec 23

3. Surface-functionalised copper oxide nanoparticles: a pathway to multidrug-resistant pathogen control in medical devices - Dr James Hall, Dr Adam Varney, Dr Samantha McLean

Surface-Functionalised Copper Oxide Nanoparticles: A Pathway to Multidrug-Resistant Pathogen Control in Medical Devices

Copper oxide nanoparticles (CuONPs) offer promising antimicrobial properties against a range of pathogens, addressing the urgent issue of antibiotic resistance. This study details the synthesis of glu...

www.mdpi.com

Antimicrobial Resistance, Omics & Microbiota (AROM) @ NTU @arom-ntu.bsky.social · Dec 23

2. Assessment of a light-curable hydrogel to be used for root canal obturation - Dr Sarah Kuehne

Sage Journals: Discover world-class research

Subscription and open access journals from Sage, the world's leading independent academic publisher.

journals.sagepub.com

1 1 1

Antimicrobial Resistance, Omics & Microbiota (AROM) @ NTU @arom-ntu.bsky.social · Dec 23

Great end to the year for @arom-ntu.bsky.social, with three new publications out.

1. Shared mechanisms of enhanced plasmid maintenance and antibiotic tolerance mediated by the VapBC toxin:antitoxin system - @mcvickermicro.bsky.social, Dr Jonathan Thomas

Shared mechanisms of enhanced plasmid maintenance and antibiotic tolerance mediated by the VapBC toxin:antitoxin system | mBio

Our work addresses two processes, the maintenance of plasmids and antibiotic tolerance; both contribute to the development of antimicrobial resistance in bacteria that cause human disease. Here, we fo...

journals.asm.org

1 2 5

Reposted by Antimicrobial Resistance, Omics & Microbiota (AROM) @ NTU

Listen, Engage and Analyse with the Public (LEAP) @leapntu.bsky.social · Dec 9

At Nottingham Trent University (NTU), we’re tackling some of the biggest health challenges in society; dementia, cancer, diabetes, obesity, and infections. But we can’t do it alone.
Through our LEAP (Learn, Engage and Analyse with the Public) initiative, we want to hear your thoughts and (1/3)

A blue and white poster with details of the launch event for the NTU LEAP initiative to listen, engage and analyse with the public for bioscience research.

1 7 6