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Adrien Schahl @aschahl.bsky.social · 4d

No worries, we'll choke during the boxing day as usual.

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Adrien Schahl @aschahl.bsky.social · 14d

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Reposted by Adrien Schahl

Biophysical Society @biophysicalsoc.bsky.social · 14d

Erdinc Sezgin to Receive 2026 Early Independent Career Award
www.biophysics.org/news-room/er...

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Reposted by Adrien Schahl

CNRS @cnrs.fr · 15d

🔬 Sophie Sacquin-Mora, biochimiste, étudie les protéines pour comprendre leur fonctionnement et prédire leurs comportements liés à certaines maladies. Des recherches qui offrent l’espoir de trouver de nouveaux médicaments et traitements médicaux.

Brève de science : au cœur des protéines

Faut-il forcément des microscopes et des tubes à essai pour observer des molécules ou des protéines ?

www.cnrs.fr

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Reposted by Adrien Schahl

Olivier Neyrolles @oneyrolles.bsky.social · 16d

Excited to share Wendy Le Mouëllic’s PhD work, now published in @pnas.org!
It reveals that M. tuberculosis depends on inorganic sulfate import to survive inside host cells—fueling essential processes such as redox balance and stress resistance.
Huge congrats to Wendy & colleagues!
shorturl.at/WbFQC

Inorganic sulfate is critical for Mycobacterium tuberculosis lung tissue colonization and redox balance | PNAS

Tuberculosis remains the deadliest infectious disease caused by a single pathogen, highlighting the urgent need for novel therapies. A deeper under...

www.pnas.org

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Adrien Schahl @aschahl.bsky.social · 17d

Ils ont mis la recette à la fin de l'article si vous êtes intéressé 😋

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Adrien Schahl @aschahl.bsky.social · 19d

It most likely means that you've never been threatened by such attacks. Not understanding is just a marker of how privileged you are, and by extension how you don't care about threatened people.

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Adrien Schahl @aschahl.bsky.social · 19d

Quite fun, and then you realise that it's most likely a postdoc that would have to do this experiment 🙃

Reposted by Adrien Schahl

Michael Way @drmichaelway.bsky.social · 23d

And now for something completely different @tianyang22.bsky.social & #YanCao uncover of how SPIN90 dimers activate Arp2/3 to nucleate bidirectional linear actin filaments. Great collaboration with @romet-jegou-lab.bsky.social & @carolynmoores1.bsky.social #Cryo-EM #Arp2/3 rdcu.be/eGoH4

Arp2/3-mediated bidirectional actin assembly by SPIN90 dimers

Nature Structural & Molecular Biology - Liu et al. show that SPIN90 dimerizes and binds two Arp2/3 complexes to nucleate two bidirectional actin filaments and the dimerization domain is...

rdcu.be

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Adrien Schahl @aschahl.bsky.social · 24d

Et vice et versa.

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Reposted by Adrien Schahl

André Nadler @nadlerlab.bsky.social · Aug 21

Out today in @nature.com: Together with the Honigmann, Shevchenko, Drobot and Hof labs, we present a general workflow for imaging the localization and transport of individual lipids in cells and mapping their metabolism.
www.nature.com/articles/s41...

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Adrien Schahl @aschahl.bsky.social · 26d

Va falloir tout doucement se mettre a y jouer en fait 😇

Adrien Schahl @aschahl.bsky.social · 28d

Bah voilà, au début tout va bien avec PSMA3 qui correspond à la sous unite A3 et puis tout a coup tu comprends pas pourquoi, mais PSMB4 c'est B7 et PSMB8 c'est B5i dans l'immunoproteasome.

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Adrien Schahl @aschahl.bsky.social · 28d

T'as déjà jeté un oeil au bordel infini du nom des sous unités du proteasome et la comparaison avec le nom des gènes correspondant ?

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Reposted by Adrien Schahl

Erdinc Sezgin @sciezgin.bsky.social · Sep 8

Previous preprint is now published in RSC Chemical Biology.
If you are interested in plasma membrane labeling, see the paper! 👇
pubs.rsc.org/en/content/a...

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Reposted by Adrien Schahl

Böckmann Lab @biomemphys.bsky.social · Sep 4

We're hiring! Join our team at @fau.de ! We are seeking an enthusiastic candidate for a PhD position in our lab specializing in cutting-edge theoretical and computational membrane biophysics.
Please send your CV, and a statement of research interests via email.
www.biomemphys.nat.fau.de/jobs/

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Reposted by Adrien Schahl

Matthieu Chavent @matthchavent.bsky.social · Aug 30

our article "How PGL finds a sweet spot in phospholipid membranes: A combined multiscale MD and NMR study" is now freely available in its final version in @biophysj.bsky.social

www.sciencedirect.com/science/arti...

How PGL finds a sweet spot in phospholipid membranes: A combined multiscale MD and NMR study

Glycolipids from pathogenic Mycobacterium tuberculosis play important roles during the interaction of the pathogen with macrophages and can shape the …

www.sciencedirect.com

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Adrien Schahl @aschahl.bsky.social · Aug 27

J'avoue, j'ai soufflé du nez en lisant ça 😂

Adrien Schahl @aschahl.bsky.social · Aug 23

🤯🤯🤯 j'en avais aucune idée mais j'avais deja remarqué ça chez moi aussi. Du coup je suis allé voir et effectivement je savais pas que c'était quelque chose de caractérisé 😮

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Adrien Schahl @aschahl.bsky.social · Aug 22

Many thanks to our colleagues: Shengpan Zhang, Quentin Sattentau, Marta Carroni, and last but not least to the incredible MD wizard
@nandanhaloi.bsky.social
for their help along the project!

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Adrien Schahl @aschahl.bsky.social · Aug 22

New preprint about my work done under the direction of @sciezgin.bsky.social, @delemottelab.bsky.social and Rebecca Howard.
We studied the opening process of ADAM10 enhanced sampling MD, MSM and Fluorescence microscopy!
Let us know what you think about it 😁

www.biorxiv.org/content/10.1...

Lipid-facilitated opening of the ADAM10 sheddase revealed by enhanced sampling simulations

ADAM10 is a crucial membrane-bound metalloprotease that regulates cellular physiology by cleaving and releasing membrane-anchored proteins, including adhesion molecules and growth factor precursors, t...

www.biorxiv.org

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Reposted by Adrien Schahl

Siewert-Jan Marrink @cg-martini.bsky.social · Aug 20

Cool simulations from my former PhD student Petteri Vainikka now published: "Molecular Dynamics Simulation of Fatty Acid Extraction Using a Type V Deep Eutectic Solvent with Tunable Hydrophobicity" | The Journal of Physical Chemistry B pubs.acs.org/doi/full/10....

Molecular Dynamics Simulation of Fatty Acid Extraction Using a Type V Deep Eutectic Solvent with Tunable Hydrophobicity

Deep eutectic solvents (DESs) are often promoted as a more environmentally friendly alternative for ionic liquids and other ionic solvents. Like ionic liquids, DESs can be designed for specific tasks ...

pubs.acs.org

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Adrien Schahl @aschahl.bsky.social · Aug 14

Kilodeath

Adrien Schahl @aschahl.bsky.social · Aug 11

Weird lipids, weird effects on membranes ! Happy to see this story out 😄
If you like MD simulations, NMR spectroscopy and membranes this story will interest you 😊

Matthieu Chavent @matthchavent.bsky.social · Aug 7

our new article combining MD and NMR to understand the positioning of phenolic glycolipids from mycobacteria in phospholipid membranes is now in @biophysj.bsky.social ! 🥳

"How PGL finds a sweet spot in phospholipid membranes – a combined multiscale MD and NMR study"

www.cell.com/biophysj/abs...

How PGL finds a sweet spot in phospholipid membranes – a combined multiscale MD and NMR study

Glycolipids from pathogenic Mycobacterium tuberculosis (Mtb) play important roles during the interaction of the pathogen with macrophages, and can shape the host cell’s immune response by modulating i...

www.cell.com

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Reposted by Adrien Schahl

Siewert-Jan Marrink @cg-martini.bsky.social · Aug 1

A true community effort ! The Martini 3 Lipidome: Expanded and Refined Parameters Improve Lipid Phase Behavior | ACS Central Science pubs.acs.org/doi/10.1021/...

pubs.acs.org

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