Alejandro Tejada Arranz
@atejadaarranz.bsky.social
Bacterial pathogenesis🦠, antimicrobial resistance, phenotypic heterogeneity, T6SS 🔬
Postdoc at the Basler lab, Biozentrum, University of Basel, NCCR-AntiResist 🇨🇭
Former PhD at Institut Pasteur with Hilde de Reuse 🇫🇷
Postdoc at the Basler lab, Biozentrum, University of Basel, NCCR-AntiResist 🇨🇭
Former PhD at Institut Pasteur with Hilde de Reuse 🇫🇷
Reposted by Alejandro Tejada Arranz
🙌 Congratulations to @atejadaarranz.bsky.social @basler-lab.bsky.social and Jenal Lab for this new @nccr-antiresist.bsky.social paper, another learning step about previously unknown bacterial vulnerabilities.
#TransformingAntimicrobialResearch #AMR
#TransformingAntimicrobialResearch #AMR
🧪 New research by @basler-lab.bsky.social reveals a surprising microbial trade-off: Pseudomonas aeruginosa activates a defense program to survive “speargun” attacks from rival bacteria, but this defense makes it more vulnerable to antibiotics. @unibas.ch @snsf.ch @nccr-antiresist.bsky.social 👇
How bacteria resist hostile attacks
Some bacteria use a kind of molecular “speargun” to eliminate their rivals, injecting them with a lethal cocktail. Researchers led by Prof. Marek Basler at the Biozentrum have now discovered that cert...
www.biozentrum.unibas.ch
December 9, 2025 at 8:06 AM
🙌 Congratulations to @atejadaarranz.bsky.social @basler-lab.bsky.social and Jenal Lab for this new @nccr-antiresist.bsky.social paper, another learning step about previously unknown bacterial vulnerabilities.
#TransformingAntimicrobialResearch #AMR
#TransformingAntimicrobialResearch #AMR
Our paper is finally out! Check it out here 👇
Big congrats to @atejadaarranz.bsky.social and co-authors on this paper showing novel insights into the resistance to #T6SS effectors and an unexpected link to antibiotic resistance!
Thanks @nccr-antiresist.bsky.social for funding and supporting the collaboration with the Jenal lab!
rdcu.be/eShqI
Thanks @nccr-antiresist.bsky.social for funding and supporting the collaboration with the Jenal lab!
rdcu.be/eShqI
Mechanisms of Pseudomonas aeruginosa resistance to type VI secretion system attacks
Nature Communications - Pseudomonas aeruginosa H1-T6SS delivers effectors in response to exogenous T6SS attacks. In this study, a CRISPRi screen identifies pathways involved in P. aeruginosa...
rdcu.be
November 29, 2025 at 2:27 PM
Our paper is finally out! Check it out here 👇
Reposted by Alejandro Tejada Arranz
Big congrats to @atejadaarranz.bsky.social and co-authors on this paper showing novel insights into the resistance to #T6SS effectors and an unexpected link to antibiotic resistance!
Thanks @nccr-antiresist.bsky.social for funding and supporting the collaboration with the Jenal lab!
rdcu.be/eShqI
Thanks @nccr-antiresist.bsky.social for funding and supporting the collaboration with the Jenal lab!
rdcu.be/eShqI
Mechanisms of Pseudomonas aeruginosa resistance to type VI secretion system attacks
Nature Communications - Pseudomonas aeruginosa H1-T6SS delivers effectors in response to exogenous T6SS attacks. In this study, a CRISPRi screen identifies pathways involved in P. aeruginosa...
rdcu.be
November 28, 2025 at 10:29 PM
Big congrats to @atejadaarranz.bsky.social and co-authors on this paper showing novel insights into the resistance to #T6SS effectors and an unexpected link to antibiotic resistance!
Thanks @nccr-antiresist.bsky.social for funding and supporting the collaboration with the Jenal lab!
rdcu.be/eShqI
Thanks @nccr-antiresist.bsky.social for funding and supporting the collaboration with the Jenal lab!
rdcu.be/eShqI
Reposted by Alejandro Tejada Arranz
Very happy to see this work published! We unveil a plasmid-chromosome crosstalk by showing that pOXA-48 encodes for a regulator that mediates the transcription of an enterobacterial chromosomal operon, resulting in a growth benefit for the plasmid-carrying bacteria!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
A plasmid-chromosome crosstalk in multidrug resistant enterobacteria - Nature Communications
The authors describe a new crosstalk between a globally disseminated carbapenem resistance plasmid and clinical enterobacteria clones. This crosstalk provides a fitness advantage to the plasmid-carryi...
www.nature.com
January 2, 2025 at 11:20 AM
Very happy to see this work published! We unveil a plasmid-chromosome crosstalk by showing that pOXA-48 encodes for a regulator that mediates the transcription of an enterobacterial chromosomal operon, resulting in a growth benefit for the plasmid-carrying bacteria!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Alejandro Tejada Arranz
Podemos solicitar juntos este contrato predoctoral si quieres hacer la tesis en Ecología y Evolución de la Resistencia a los Antibióticos.
www.cnb.csic.es/index.php/es...
Más info en 🐥👇
www.cnb.csic.es/index.php/es...
Más info en 🐥👇
December 4, 2024 at 2:24 PM
Podemos solicitar juntos este contrato predoctoral si quieres hacer la tesis en Ecología y Evolución de la Resistencia a los Antibióticos.
www.cnb.csic.es/index.php/es...
Más info en 🐥👇
www.cnb.csic.es/index.php/es...
Más info en 🐥👇
Just joined the party here 🥳
So I drop here my last pre-print as well! More to come on this soon!
www.biorxiv.org/content/10.1...
So I drop here my last pre-print as well! More to come on this soon!
www.biorxiv.org/content/10.1...
Mechanisms of P. aeruginosa resistance to Type VI Secretion System attacks
The Type VI Secretion Systems (T6SSs) is a molecular nanomachine that injects toxic effector proteins into the environment or neighbouring cells, and thus plays an important role in interbacterial com...
www.biorxiv.org
November 24, 2024 at 3:23 PM
Just joined the party here 🥳
So I drop here my last pre-print as well! More to come on this soon!
www.biorxiv.org/content/10.1...
So I drop here my last pre-print as well! More to come on this soon!
www.biorxiv.org/content/10.1...