Aaron Puri
@awpuri.bsky.social
35 followers 36 following 5 posts
Assistant Professor in the University of Utah Department of Chemistry and the Henry Eyring Center for Cell and Genome Science. Interested in natural products and bacterial interactions. https://purilab.utah.edu/
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awpuri.bsky.social
This siderophore can be used by another methane-oxidizing bacterium from the same community that doesn't produce it, and provides a molecular link between iron speciation in the environment and methane oxidation
awpuri.bsky.social
We applied InverSIP to a methane-oxidizing bacterial community to identify an iron-chelating secondary metabolite (siderophore) used by methane-oxidizing bacteria to acquire insoluble ferric iron from their environment
awpuri.bsky.social
We combined stable isotope probing with the inverse labeling method we have been using to link biosynthetic genes to their products in a method we call InverSIP
Reposted by Aaron Puri
wbrazelton.bsky.social
It has been great fun to work with Aaron Puri's team @awpuri.bsky.social on this project. InverSIP is a clever tool for linking genotype and phenotype.

Inverse stable isotope probing–metabolomics (InverSIP) identifies an iron acquisition system in a methane-oxidizing... www.pnas.org/doi/10.1073/...
www.pnas.org
awpuri.bsky.social
Proud to announce “RefAHL,” an updated, curated collection of LuxI-type quorum sensing signal synthases with their products and associated metadata. RefAHL is publicly available to help catalog LuxI-type diversity encoded in (meta) genomic data.

journals.asm.org/doi/10.1128/...
journals.asm.org