James Beeson
beesonmalaria.bsky.social
James Beeson
@beesonmalaria.bsky.social
Public Health Physician and Researcher. Malaria, maternal and child health, global health.
New study shows Plasmodium falciparum evades immune attack by varying invasion ligands. Antibodies target PfRH1 & PfRH2b, but variation limits efficacy. Multi-target vaccines may be key to blocking blood-stage malaria. #Malaria #Immunology #VaccineResearch
www.frontiersin.org/journals/imm...
Frontiers | Plasmodium falciparum reticulocyte-binding homologues are targets of human inhibitory antibodies and play a role in immune evasion
www.frontiersin.org
May 21, 2025 at 1:53 AM
New study shows Plasmodium falciparum evades immune attack by varying invasion ligands. Antibodies target PfRH1 & PfRH2b, but variation limits efficacy. Multi-target vaccines may be key to blocking blood-stage malaria. #Malaria #Immunology #VaccineResearch
www.frontiersin.org/journals/imm...
Frontiers | Plasmodium falciparum reticulocyte-binding homologues are targets of human inhibitory antibodies and play a role in immune evasion
www.frontiersin.org
May 21, 2025 at 1:51 AM
Highly protective and long lasting #vaccines for #malaria may be crucial to make major gains and achieve elimination in the long term. #worldmalariaday
April 25, 2025 at 8:05 AM
On #worldmalariaday its great to be working with wonderful people in our ACREME program to find new solutions for #malaria. @acreme.bsky.social @burnetinstitute.bsky.social
We must increase funding, invest in proven interventions, build stronger health systems and drive forward innovative tools and strategies to accelerate progress towards malaria elimination goals. Read more from @freyafowkes.bsky.social 🦟shorturl.at/3dIDx #WorldMalariaDay
April 25, 2025 at 8:03 AM
Reposted by James Beeson
We must increase funding, invest in proven interventions, build stronger health systems and drive forward innovative tools and strategies to accelerate progress towards malaria elimination goals. Read more from @freyafowkes.bsky.social 🦟shorturl.at/3dIDx #WorldMalariaDay
April 23, 2025 at 12:41 AM
Reposted by James Beeson
🌍🦟 It's #WorldMalariaDay!

Join the global fight – register now for virtual participation at 'BioMalPar XXI' and access vital research + dialogue from anywhere in the world. 🌐🧪

🔗 s.embl.org/bmp25-01-bl

#EMBLMalaria #WorldMalariaDay #Malaria #MalariaConference #GlobalHealth #EndMalaria
April 25, 2025 at 7:06 AM
Reposted by James Beeson
🔧 No single tool will #EndMalaria. But when used together, the tools we have—including vaccines, medicines & bed nets—are powerful, especially as part of locally led, context-driven prevention strategies.

As #WorldMalariaDay approaches, let’s invest in what works and deliver it to all 🚀

@mmv.org
April 24, 2025 at 5:15 PM
Reposted by James Beeson
In recognition of #WorldMalariaDay, GHTC's Executive Director Dr. Kristie Mikus reflects on her own experience with malaria and urges leaders and policymakers to continue to invest in innovations to address it.

www.ghtcoalition.org/blog/malaria...
Malaria nearly took my life. Innovation may be what finally ends it, if we let it.
In recognition of World Malaria Day, GHTC Executive Director Dr. Kristie Mikus reflects on her own experience with malaria and urges leaders and policymakers to continue to invest in innovations to ad...
www.ghtcoalition.org
April 22, 2025 at 3:50 PM
Reposted by James Beeson
FROM WHO: World Malaria Day 25 April 2025 - Malaria ends with us: Reinvest, Reimagine, Reignite. A grassroots campaign to re-energize efforts at all levels to accelerate progress towards malaria elimination.

www.malariaworld.org/blogs/world-...

#malaria
#worldmalariaday
April 7, 2025 at 2:57 PM
March 12, 2025 at 2:24 AM
The value of vaccines is indisputable
March 12, 2025 at 2:22 AM
Pleased to be involved in a great new #malaria paper. Identified an i-body (antibody-like molecule) that blocks host-cell invasion. Remarkably, i-body targeted a conserved epitope on different Plasmodium species. Are pan-species therapeutics or vaccines possible?
www.nature.com/articles/s41...
A broadly cross-reactive i-body to AMA1 potently inhibits blood and liver stages of Plasmodium parasites - Nature Communications
Apical membrane antigen-1 (AMA1) is important for Plasmodium parasite invasion, but surface polymorphisms in P. falciparum AMA1 hamper vaccine and antibody development. Here the authors identify a hum...
www.nature.com
March 11, 2025 at 6:35 AM
Exciting new paper reporting the finding of a potent human monoclonal antibody against Plasmodium vivax #malaria. Blocks sporozoite infection of the liver, and blood stage replication, targets AMA1.

www.nature.com/articles/s41...
Potent AMA1-specific human monoclonal antibody against Plasmodium vivax Pre-erythrocytic and Blood Stages - Nature Communications
Here the authors isolate monoclonal antibodies specific for Plasmodium vivax apical membrane antigen 1, and characterize the epitope of one antibody that inhibits invasion of reticulocytes and hepatoc...
www.nature.com
March 11, 2025 at 6:30 AM