benallwein.bsky.social
Ben Allwein
@benallwein.bsky.social
42 followers 40 following 2 posts
Structural biology PhD student at Cornell/MSKCC studying DNA replication & membrane proteins
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jeremymberg.bsky.social
Jeremy Berg @jeremymberg.bsky.social · Apr 3
My Op-Ed in the Pittsburgh Post Gazette was posted this morning.

(Registration required, but I have posted a pdf on my dashboard)

www.post-gazette.com/opinion/gues...

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Jeremy M. Berg: Life-saving medicines begin in the basic research DOGE wants to stop funding
We should not lose sight of how wonderfully productive the biomedical research enterprise — now under threat — can be. The interplay between...
www.post-gazette.com
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benallwein.bsky.social
Ben Allwein @benallwein.bsky.social · Mar 20
A huge privilege to see @drewweissmanlab.bsky.social, 2023 Nobel laureate for developing mRNA-LNP vaccines, at MSK speaking about their future in cancer vaccines and *in vivo* CAR-T (!!!)

...at the same time as NIH has been reportedly advising grant applicants to avoid mentioning "mRNA vaccines"...
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benallwein.bsky.social
Ben Allwein @benallwein.bsky.social · Mar 6
I am so proud to share a major part of my graduate school research, published today in Science, where we use cell-free replication assays and cryo-EM to describe a central mechanism of eukaryotic DNA replication:

www.science.org/doi/10.1126/...
G-quadruplex–stalled eukaryotic replisome structure reveals helical inchworm DNA translocation
DNA G-quadruplexes (G4s) are non–B-form DNA secondary structures that threaten genome stability by impeding DNA replication. To elucidate how G4s induce replication fork arrest, we characterized fork ...
www.science.org
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