There is an un named paeds cardiac anaesthetist (DMcA) who brings back his punters on FIO2 0.23 x PIP 13 on PEEP 5 , rate 13 or 17 or 19. He just enjoys watching my ADHD AUTISTIC brain freeze and crash. He knows I cant focus on ANYTHING until i make those numbers even

Absolutely! I’m doing research with EMR data and it’s challenging. And you can’t look at the pt to see the bleeding eyeballs with a SBP of 1000!! Clinical deterioration is close to my heart (ICU). What were your conclusions?

You’d need a good machine with that many pts for MCMC to go brrrrrrr….

It sounds more impressive than it is. simstudy is a good pkg for complex data. Or you can raw-dog it.

In my world (ICU, anaesthetics & pain), most of the data is truncated +/- skewed, ordinal, & usually longitudinal. Also, the exposures are often continuous (eg drug doses), which adds complexity.

It worked well because I could explain the analysis to my collaborators and why this method was preferred.

It also allowed me to do a prior predictive check to test my priors. You can do this with a smaller sample if you’re worried about comp time.

I don’t know of any packages though.

I had an almost identical situation to this with a longitudinal RCT. I wanted to use a bivariate outcome and they wanted a t-test!

I just ran a simulation of a null study to show the trajectory plots, overall bivariate posterior distribution plots and daily bivariate posterior distribution plots.

I feel like I’m being punished for having eyes.

Good Lord, Maffy! Tone it down a smidge! There are people on here trying to doomscroll!!

2 questions:

1. Did you have midaz!?
2. How did you tolerate the parasthesiae/anaesthesia, particularly the duration of action of the block?

You can appreciate how mirror therapy works for phantom pain.

Given your article, don’t you want to see if you can taste the garlic!?!

Good luck for Friday!

Please, I don’t need the midaz!!

Good luck Gav! I opted for a block rather than a GA or sedation as well. The thought of what I would say to my colleagues with Midaz on board terrified me!!

I co wrote the first paper on the taste of garlic with thiopentone.
Much described at the time but never written up.
My claim to infamy 😊

https://pubmed.ncbi.nlm.nih.gov/8862647/

😂😂😂

One of the benefits of being particular!!!

It reads like paralysis = asleep/sedated. I hope they don’t really believe this, and this is just poor wording.

By “awake”, you mean “moving” don’t you!? None of the muscle relaxants are sedatives, so if you just give Roc/Sux alone, the patient is awake and paralysed (& probs pissed off!).