Ben Kuznets-Speck
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biophysben.bsky.social
Ben Kuznets-Speck
@biophysben.bsky.social
Biophysicist working at the edge of single cell biology, machine learning, and statistical-mechanics. Postdoc in Yogesh Goyal's lab at Northwestern; PhD in biophysics, UC Berkeley; BS in math and physics, CWRU.
Today we’re excited to share Keeping SCORE, a framework that turns any diffusion model into a thermodynamic inference machine.
Using only a model’s score function, we compute exact class likelihoods and uncertainty—and even decompose which features drove the decision. www.biorxiv.org/content/10.1...
December 2, 2025 at 1:32 AM
Excited to share my new work on using AI and measured transcriptional responses to gene perturbations (knockdowns for example) to predict which sets of genes cause/mitigate complex disease phenotypes like cancer metastasis, IBD, or asthma, out now in PNAS! www.pnas.org/doi/full/10....
September 23, 2025 at 1:59 PM