Biorecognition group
@biorecognition.bsky.social
Biorecognition group, Department of Biomedicine, University of Bergen, Norway.
We love proteins!
We love proteins!
The importance of the J-domain protein DNAJC12 in dopamine deficiencies has been identified: Its interaction with tyrosine hydroxylase is essential to stabilize the enzyme, prevent aggregate formation and maintain dopamine synthesis.
The article in NatureComms go.nature.com/4kWQgEy
The article in NatureComms go.nature.com/4kWQgEy
Structural recognition and stabilization of tyrosine hydroxylase by the J-domain protein DNAJC12 - Nature Communications
DNAJC12 variants cause parkinsonism. Here, the authors show that DNAJC12 stabilizes tyrosine hydroxylase, a crucial enzyme in dopamine synthesis, and identify key structural motifs for this interactio...
go.nature.com
March 24, 2025 at 1:54 PM
The importance of the J-domain protein DNAJC12 in dopamine deficiencies has been identified: Its interaction with tyrosine hydroxylase is essential to stabilize the enzyme, prevent aggregate formation and maintain dopamine synthesis.
The article in NatureComms go.nature.com/4kWQgEy
The article in NatureComms go.nature.com/4kWQgEy
Reposted by Biorecognition group
Identifican la importancia de la chaperona DNAJC12 en enfermedades neurodegenerativas similares al Parkinson: Su interacción con la enzima TH es esencial para estabilizar la enzima y que no se formen agregados
Más info bit.ly/41KYAyr
El artículo en NatureComms go.nature.com/4kWQgEy
Más info bit.ly/41KYAyr
El artículo en NatureComms go.nature.com/4kWQgEy
March 21, 2025 at 10:33 AM
Identifican la importancia de la chaperona DNAJC12 en enfermedades neurodegenerativas similares al Parkinson: Su interacción con la enzima TH es esencial para estabilizar la enzima y que no se formen agregados
Más info bit.ly/41KYAyr
El artículo en NatureComms go.nature.com/4kWQgEy
Más info bit.ly/41KYAyr
El artículo en NatureComms go.nature.com/4kWQgEy